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公开(公告)号:US11065294B2
公开(公告)日:2021-07-20
申请号:US14891284
申请日:2014-05-15
发明人: Joon Seok Byun , Sae Kwang Ku , Ki Cheul Sohn , Seung Mo Kim , Chang Hyeong Lee , Dae Sung Hyun , Jong Dae Kim , Sung Hwan Park , Min A. Kwak
IPC分类号: A61K36/9068 , A61K31/138 , A61K36/232 , A61K36/484 , A61K36/725 , A61K36/00 , A61K31/44 , A61K31/4412 , A61K31/5377 , A61K36/28 , A61K36/53 , A61K36/65 , A61K36/752 , A61K36/756 , A61K36/88
摘要: Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang. More particularly, provided is a composition for treating a neoplastic disease by administering an anticancer agent into an individual, and administering an oriental medicine into the individual within 30 minutes. The composition remarkably reduces side effects occurring when the anticancer agent is administered alone by co-administration of the oriental medicine, reduces cytotoxicity, and has higher anticancer activity than that when the anticancer agent is administered alone.
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公开(公告)号:US10342835B2
公开(公告)日:2019-07-09
申请号:US15969762
申请日:2018-05-02
发明人: Chang Hyeong Lee , Sang Gyung Kim , Im Hee Shin , Seung Mo Kim , Joon Seok Byun , Ki Cheul Sohn , Sae Kwang Ku
IPC分类号: A61K38/19 , A61K36/232
摘要: The present invention relates to a composition for promoting proliferation of bone marrow derived stem cells using an angelicae gigantis radix extract, and more particularly, to a composition which administers a granulocyte colony-stimulating factor into an object, and administers the angelicae gigantis radix extract to the object to promote the proliferation of the bone marrow derived stem cells. The composition of the present invention solves side effects such as splenomegaly which were caused by a method of administering only the G-CSF for proliferation and differentiation of the stem cells, thereby significantly mitigating the side effects through co-administration of the angelicae gigantis radix extract, and further promoting the proliferation and the differentiation of the stem cells.
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公开(公告)号:US10286040B2
公开(公告)日:2019-05-14
申请号:US15854613
申请日:2017-12-26
发明人: Chang Hyeong Lee , Sang Gyung Kim , Im Hee Shin , Seung Mo Kim , Joon Seok Byun , Ki Cheul Sohn , Sae Kwang Ku
IPC分类号: A61K38/00 , A61K38/19 , C12N5/0789 , A61K36/804 , A61K36/076 , A61K36/232 , A61K36/234 , A61K36/258 , A61K36/284 , A61K36/484 , A61K36/65 , A61K36/07 , A61K36/64
摘要: The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and more specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.
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