公开(公告)号：US20230043437A1

公开(公告)日：2023-02-09

申请号：US17790646

申请日：2021-01-05

申请人： NANTONG UNIVERSITY

发明人： Xiaosong GU ,  Chunkang TANG ,  Fei DING ,  Xiaoming YANG ,  Qiong CHENG ,  Hualin SUN ,  Lai XU

IPC分类号： A61K36/481 ,  A61K36/64 ,  A61K36/21 ,  A61K36/725 ,  A61K36/815 ,  A61K36/232 ,  A61K36/286 ,  A61K36/076 ,  A61K36/284

摘要： Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.

公开(公告)号：US20220226413A1

公开(公告)日：2022-07-21

申请号：US17693327

申请日：2022-03-12

申请人： Chenland Nutritionals, Inc. ,  Qingdao Chenland Biological Technology Co., ltd.

发明人： Shengcan Zou ,  Shanglong Wang ,  Xin Li ,  Lei Zong ,  Jiancheng Zong ,  Zengliang Zhang

IPC分类号： A61K36/69 ,  A61K36/8988 ,  A61K36/882 ,  A61K36/64 ,  A61K47/69

摘要： The present disclosure relates to the technical field of traditional Chinese medicine, and more specifically, to a traditional Chinese medicine composition with improving cognition effect, its preparation method and a traditional Chinese medicine preparation. In parts by weight, the traditional Chinese medicine composition is made from 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia Willd., 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. The pharmacodynamic substances of Gastrodiae Rhizoma, Polygala tenuifolia Willd., Acorus tatarinowii, Cistanche deserticola Ma and Rehmanniae Radix Praeparata are extracted completely, concentrated and dried as much as possible. The volatile oil of Acorus tatarinowii and curcumin are encapsulated and dried by the volatile oil encapsulation technology. The dry powder of the traditional Chinese medicine compound extract is evenly mixed with the volatile oil encapsulation compound.

公开(公告)号：US11382935B2

公开(公告)日：2022-07-12

申请号：US17554052

申请日：2021-12-17

申请人： Sang Hee Kim ,  Hyun Kee Kim

发明人： Seon Ah Ha

IPC分类号： A61K36/64 ,  A61K35/64 ,  A61P25/00 ,  A61K31/704

摘要： The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by Aβ (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.

公开(公告)号：US11298392B2

公开(公告)日：2022-04-12

申请号：US17010871

申请日：2020-09-03

申请人： Da-Tong Ju

发明人： Wei-Te Cheng ,  Chen-Yu Lee ,  Yan-Chih Liao ,  Chi-Tun Tang ,  Chuang-Hsin Chiu ,  Hsin-I Ma ,  Da-Tong Ju ,  Tung-Han Tsai

IPC分类号： A61K36/324 ,  A61K36/232 ,  A61K36/236 ,  A61K36/64 ,  A61K36/65 ,  A61K36/736 ,  A61K36/286 ,  A61K36/35 ,  A61K36/11 ,  A61K36/21 ,  A61K36/539 ,  A61K36/718 ,  A61K36/756 ,  A61K36/07 ,  A61K36/884 ,  A61K36/284 ,  A61K36/8988 ,  A61K36/75 ,  A61K36/13 ,  A61K36/237 ,  A61K36/233 ,  A61K36/752 ,  A61K36/88 ,  A61K36/258 ,  A61K36/714 ,  A61K36/61 ,  A61K36/605 ,  A61K36/484 ,  A61K36/328

摘要： The present invention relates to a method for treating glioblastoma multiforme including administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture including Boswellia sacra, Commiphora molmol, Angelica sinensis, Ligusticum striatum, Rehmannia glutinosa, Paeonia veitchii, Prunus persica, and Carthamus tinctorius.

公开(公告)号：US20220054569A1

公开(公告)日：2022-02-24

申请号：US16995903

申请日：2020-08-18

申请人： Da-Tong JU

发明人： Hsuan-Ching TSENG ,  Da-Tong JU ,  Sung-Sen YANG ,  Wei-Te CHENG ,  Chen-Yu LEE ,  Yan-Chih LIAO ,  Juei-Yang LO ,  Luan-Yao CHIEN

IPC分类号： A61K36/282 ,  A61K36/808 ,  A61K36/40 ,  A61K36/284 ,  A61K36/756 ,  A61K36/484 ,  A61K36/64 ,  A61K36/8945 ,  A61K36/076 ,  A61K36/65 ,  A61K36/81 ,  A61K36/31 ,  A61K36/21

摘要： A method for treating a side effect caused by bacillus Calmette-Guérin (BCG) perfusion therapy for bladder cancer includes: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture comprising Rhizoma anemarrhenae, Cortex phellodendri, Glycyrrhiza uralensis, Rehmanniae Radix, Fructus corni, Rhizoma dioscoreae, Poria, Moutan cortex, Rhizoma Alismatis, Radix achyranthis bidentatae, and Atractylodes lancea.

公开(公告)号：US20220031626A1

公开(公告)日：2022-02-03

申请号：US17450836

申请日：2021-10-14

申请人： Haowei Ti

发明人： Haowei Ti ,  Shiqi Mei ,  Donghai Mei

IPC分类号： A61K9/50 ,  A61K36/748 ,  A61K36/539 ,  A61K36/533 ,  A61K36/64 ,  A61K36/59 ,  A61K36/9066 ,  A61K36/47 ,  A61K36/634 ,  A61K36/346 ,  A61K36/54 ,  A61K36/288

摘要： The invention relates to the technical field of traditional Chinese medicine, and discloses a method of traditional Chinese medicine and microcapsule preparation suitable for nasopharyngeal cancer tumor inhibitors. A traditional Chinese medicine suitable for nasopharyngeal cancer tumor inhibitors, including: Hedyotis Diffusa, Scutellaria Barbata, Arrowshaped Tinospora Root, Rehmanniae Radix Preparata, Radix Curcumae, Crotonis Fructus, Leonurus Artemisia, Ramulus Cinnamomi, Forsythiae Fructus, Taraxacum, Radix Platycodonis and White Vinegar. Among them, the raw materials for the weight ratio are as follows: 60 grams of Hedyotis Diffusa, 30 grams of Scutellaria Barbata, 9-12 grams of Arrowshaped Tinospora Root, 18 grams of Rehmanniae Radix Preparata, 19 grams of Radix Curcumae, 7.5 grams of Crotonis Fructus, 10 grams of Leonurus Artemisia, 7-10 grams of Ramulus Cinnamomi, 10 grams of Forsythiae Fructus, 15-30 grams of Taraxacum, 10 g of Radix Platycodonis, and 30 ml of White Vinegar.

公开(公告)号：US11235018B2

公开(公告)日：2022-02-01

申请号：US16249501

申请日：2019-01-16

申请人： OKCHUNDANG CO., LTD.

发明人： Sae Kwang Ku ,  Seong Min Ku ,  Tae Hun Ku ,  Chui Jong Jung ,  Gyung Yun Beik ,  Jin Gi Shin ,  Sang Soo Lee ,  Jeong Gyun Seo ,  Chil Surk Yoon ,  Xian Li

IPC分类号： A61K36/64 ,  A61K36/258 ,  A61K36/342 ,  A61K36/076 ,  A61K31/5377 ,  A61P35/00 ,  A23L33/105 ,  A61K35/644

摘要： The present invention provides a pharmaceutical composition for preventing or treating cancer, a food composition for enhancing immune functions, and a pharmaceutical composition for preventing or treating cachexia. The composition of the present invention provides effects of further inhibiting the growth of tumors, increasing immunological activity, and suppressing cachexia caused by tumors. In addition, the composition of the present invention can obtain a synergistic effect when co-administered with an existing anticancer drug.

公开(公告)号：US11129861B2

公开(公告)日：2021-09-28

申请号：US15885122

申请日：2018-01-31

申请人： OKCHUNDANG CO., LTD.

发明人： Seong Min Ku ,  Tae Hun Ku ,  Chul Jong Jung ,  Jeong Gyun Seo ,  Hye Ran Gong ,  Sae Kwang Ku ,  Seok Man Park ,  Ryong Kong ,  Xian Li ,  Gyung Yun Beik ,  Yoeng Eun Yu ,  Hee Jeong Ryu ,  Gyu Hyeon Kim

IPC分类号： A61K36/258 ,  A61K36/342 ,  A61P13/12 ,  A61K36/07 ,  A61K36/64 ,  A61K31/70 ,  A61P17/00 ,  A61P37/08 ,  A61P7/00 ,  A61P11/06 ,  A61P27/02 ,  A61P1/02 ,  A61P27/16 ,  A61P1/00 ,  A61P11/00 ,  A61P1/04 ,  A61P15/02 ,  A61P19/06 ,  A61P19/02 ,  A61P29/00 ,  A61P1/16 ,  A61P13/10

摘要： The present invention provides a composition containing, as active ingredients, Panax ginseng, Adenophora triphylla, Wolfiporia extensa, Rehmannia glutinosa, and Mel for an antitussive, expectorant, or anti-inflammatory action, and a composition for preventing, alleviating, or treating a respiratory disease. The present invention provides a compositions having excellent effects compared with an existing antitussive agent and expectorant agent. The compositions of the present invention are a naturally derived material and has little cytotoxicity, and thus is expected to be safely used as a medicine or food composition having antitussive, expectorant, and anti-inflammatory effects.

公开(公告)号：US20210169961A1

公开(公告)日：2021-06-10

申请号：US17265724

申请日：2018-12-18

申请人： SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ,  ACADEMY OF MILITARY MEDICAL SCIENCES ,  SHANGHAI SANG LUO MEDICINE TECHNOLOGY CO., LTD.

发明人： Yueqiu Gao ,  Junjie Shan ,  Xuehua Sun ,  Man Li ,  Yanxu Chen ,  Zhenhua Zhou ,  Yating Gao ,  Hao Ma ,  Xin Zhang ,  Rui Xu ,  Dan Nie ,  Lulu Liu ,  Changwei Li ,  Yu Yang ,  Xiunan Zhao

IPC分类号： A61K36/746 ,  A61K36/074 ,  A61K36/481 ,  A61K36/71 ,  A61K36/489 ,  A61K36/537 ,  A61K36/296 ,  A61K36/64 ,  A61K36/284 ,  A61K36/752 ,  A61K36/41 ,  A61K36/488 ,  A61K36/72 ,  A61K36/53 ,  A61K36/9066 ,  A61K35/586 ,  A61K36/8984 ,  A61K36/898 ,  A61K36/48 ,  A61K36/539 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61P31/20 ,  A61P1/16 ,  A61P35/00 ,  A61K31/522 ,  A61K31/683 ,  A61K31/7072 ,  A61K31/506 ,  A23L33/105 ,  A23L33/00

摘要： Disclosed is a hepatoprotective traditional Chinese medicine composition, extract and pharmaceutical use thereof. The composition comprises Morinda officinalis How, Ganoderma lucidum (Leyss. Ex Fr.) Karst., Astragalus membranaceus (Fisch) Bge. Var. monghlicus (Bge) Hsiao, Ranunculus ternatus Thunb., Sophora flavescens Alt. and Salvia miltiorrhiza Bge. The composition and extract thereof may be used for treating liver injury, hepatitis, hepatic fibrosis, hepatic cirrhosis or liver cancer, and they may also be used as a vaccine adjuvant or an immunomodulator.

公开(公告)号：US20200368305A1

公开(公告)日：2020-11-26

申请号：US16881006

申请日：2020-05-22

申请人： YING-JIH CHAO LEE

发明人： YING-JIH CHAO LEE

IPC分类号： A61K36/64 ,  A61K36/40 ,  A61K36/8945 ,  A61K36/884 ,  A61K36/65 ,  A61K36/076 ,  A61K36/714 ,  A61K36/54 ,  A61P3/06

摘要： An herbal formula used for preparing a pharmaceutical composition for preventing and treating metabolic syndrome is provided. The herbal formula includes Rehmanniae radix preparata, Cornus officinalis, Dioscorea polystachya, Alisma plantago-aquatica, Paeonia suffruticosa, Poria cocos, Aconitum carmichaeli, and Cinnamomum cassia.