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公开(公告)号：US20240301336A1
公开(公告)日：2024-09-12
申请号：US18571999
申请日：2022-06-14
Applicant: CORNING INCORPORATED
Inventor： Thomas Albert Cloutier , William Joseph Lacey , Ana Maria del Pilar Pardo , Allison Jean Tanner
Abstract: A protective carrier for a microcavity vessel is provided. The protective carrier comprises a substantially flat rigid plate comprising a top surface and a bottom surface. A flange disposed around at least a portion of a perimeter of the rigid plate, the flange extending from the top surface of the rigid plate. One or more ribs disposed on the bottom surface of the rigid plate. A protective microcavity vessel carrier system is provided that comprises a microcavity vessel comprising a microcavity substrate on a bottom surface; and a protective carrier. The microcavity vessel may be a microcavity flask, microcavity plate such as an open well reservoir plate, microcavity bioreactor, or a stacked 3D microcavity culture vessel.
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公开(公告)号：US20240336886A1
公开(公告)日：2024-10-10
申请号：US18292184
申请日：2022-07-29
Applicant: CORNING INCORPORATED
Inventor： Thomas Albert Cloutier , William Joseph Lacey , Ana Maria del Pilar Pardo , Allison Jean Tanner
Abstract: A baffle (130) configured to be disposed in a cell culture vessel is provided. The cell culture vessel (100) may comprise a vessel body (101) comprising a bottom wall (110) and a plurality of side walls (107) that define a cell culture chamber, the bottom wall comprising a cell culture surface (111). The baffle (130) may be configured to be disposed parallel to the cell culture surface (111) within the vessel body, the baffle comprising a first baffle crossbar (133) extending across a length of the cell culture surface; a second baffle crossbar intersecting (135) the first baffle crossbar; and a third crossbar disposed (137) at an end of the first baffle crossbar.
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公开(公告)号：US20230272325A1
公开(公告)日：2023-08-31
申请号：US18018202
申请日：2021-07-14
Applicant: CORNING INCORPORATED
Inventor： Thomas Albert Cloutier , Gregory Roger Martin
Abstract: A multi-position support for a multi-layer cell culture apparatus includes a primary base that rests against a support member in an upright configuration. A support surface is offset vertically from the primary base in the upright configuration. The support surface supports the multi-layer cell culture apparatus with the multi-layer cell culture apparatus located thereon. An intermediate surface extends between the primary base and the support surface. The intermediate surface meets the primary base at an interface that extends at an oblique angle to sides of the primary base. The multi-position support has a tilted configuration where the multi-position support is rotated about the interface such that the support surface is closer to the support member than in the upright configuration with the support surface supporting the multi-layer cell culture apparatus thereon.
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公开(公告)号：US20230257690A1
公开(公告)日：2023-08-17
申请号：US18018418
申请日：2021-07-28
Applicant: CORNING INCORPORATED
Inventor： Scott Matthew Bennett , Thomas Albert Cloutier , William Joseph Lacey , Gregory Roger Martin , Allison Jean Tanner
Abstract: A cell culture system for culturing cells is provided. The cell culture system including a cell culture vessel with a cell culture chamber for culturing cells, an inlet through which liquid can flow for filling the cell culture vessel, and an outlet through which fluid can exit the cell culture vessel. The system also includes at least one fill sensor arranged to detect liquid within the cell culture vessel reaching a fill level at a predetermined position of the cell culture vessel during filling of the cell culture vessel, where the at least one fill sensor can generate a detection signal when liquid within the cell culture vessel reaches the fill level. Also included is an actuator to change an orientation of the cell culture vessel in response to the detection signal.
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