公开(公告)号：US20230349867A1

公开(公告)日：2023-11-02

申请号：US18350588

申请日：2023-07-11

Applicant: Cytiva Sweden AB

Inventor： Nils Stafstrom ,  Lars Olof Nils Rosengren ,  Kerstin Elisabet Erickson ,  Tomas Yngve Agren ,  Yngve L. Hareland ,  Tim Francois ,  Anita Jonsson ,  Jeanne Cheng ,  Anna Andersson

IPC: G01N30/44 ,  G01N30/32 ,  G01N30/46 ,  G01N30/60 ,  G01N30/86

CPC classification number: G01N30/44 ,  G01N30/32 ,  G01N30/46 ,  G01N30/6052 ,  G01N30/8696 ,  G01N2030/326

Abstract: Disclosed is a chromatography system (100) comprising: plural modules (1-25) including at least one pump and a column valve unit (8) connectable to plural chromatography columns; and a controller (600), the controller being operable to control the or each pump and the column valve to perform different chromatographic processes, including chromatography employing just one column, as well as chromatography employing just one column, as well as chromatography employing two or more columns by selective valve opening in said unit. The system includes a housing (110) into which the plural modules (1-25) are interchangeably mountable in apertures of one generally vertical face of housing, the modules are adapted for selective fluidic interconnection by tubing substantially at said one face such that in use the modules and tubing occupy a generally vertically extending volume to minimize the footprint of the system.

公开(公告)号：US20230258616A1

公开(公告)日：2023-08-17

申请号：US18006769

申请日：2021-08-09

Applicant: CYTIVA SWEDEN AB

Inventor： Olle Bjernulf ,  Tomas Yngve Agren

IPC: G01N30/60 ,  G01N30/80

CPC classification number: G01N30/6004 ,  G01N30/80

Abstract: The present invention relates to a nozzle assembly 200 for a fraction collection unit 120 configured to collect one or more fluid samples, said nozzle assembly comprising a conduit adapter 210 configured to fluidly couple to a conduit, a nozzle body 220, wherein the nozzle body comprises at least a nozzle part 221 configured to release drops of the one or more collected fluid samples at a tip 223 of the nozzle part 221, and an interface part 222 configured to mechanically couple the assembly 200 to the fraction collection unit, wherein the assembly, when the conduit adapter 210 is attached to the nozzle body 220, forms a fluid channel from an inlet 219 of the conduit adapter 210 to the tip 223 of the nozzle part 221.

公开(公告)号：US20230347262A1

公开(公告)日：2023-11-02

申请号：US17997874

申请日：2021-06-21

Applicant: CYTIVA SWEDEN AB

Inventor： Mats Lundkvist ,  Tomas Yngve Agren ,  Erik Nilsson ,  Sebastian Skoglund

IPC: B01D15/24

CPC classification number: B01D15/247

Abstract: The invention relates to a fraction collector apparatus (100) comprising: a support system (1, 2), a carrier (42) moveably supported by the support system (1, 2), an extension arm (3) connected to the carrier (42), at least one dispensing head (31) for dispensing droplets and moveably connected to the extension arm (3), wherein the dispensing head (31) and (carrier 42) are configured to move relative to the support system in a first plane, a tray area (11) designed to support at least one rack (6, 7), wherein the at least one rack (6, 7) is designed to hold at least one collection vessel (12, 14), wherein motion of said carrier (42) is achieved by a linear bearing Y-slide unit (41) wherein the linear bearing Y-slide unit (41) is arranged underneath a linear bearing Y-rail (40) and wherein the carrier (42) is attached to the linear bearing Y-slide unit (41).