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公开(公告)号：US12066413B2
公开(公告)日：2024-08-20
申请号：US17294710
申请日：2019-12-04
Applicant: Cytiva Sweden AB
Inventor： Daniel Salomonsson , Mats Lundkvist
CPC classification number: G01N30/6082 , B01D15/206 , B01D15/22
Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.
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公开(公告)号：US11547956B2
公开(公告)日：2023-01-10
申请号：US16622524
申请日：2018-06-28
Applicant: Cytiva Sweden AB
Inventor： Mats Lundkvist , Bjorn A. Johansson , Tim Francois
IPC: B01D15/22 , F16L37/138 , F16L37/56 , G01N30/60 , G01N30/02
Abstract: Disclosed are chromatography systems employing a releasable coupling (100) for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component (110) for accepting a fluid tubing (30), said inner component including a resiliently deflectable portion (118) arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar (130) having and internal through-aperture (132) for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange (134) extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.
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公开(公告)号：US20220244227A1
公开(公告)日：2022-08-04
申请号：US17727375
申请日：2022-04-22
Applicant: CYTIVA SWEDEN AB
Inventor： Stefan Dargy , Olle Bjernulf , Mats Lundkvist
Abstract: Disclosed is a fraction collector for dispensing liquids into plural receptacles (P1,P2) arranged in a two dimensional array. The fraction collector comprises a table (22) for supporting said receptacles, and an arm supported above the table, in tum supporting a liquid dispenser (35), the fraction collector arm is rotatable about an arm axis (C) and the liquid dispenser is movable along the arm on a carriage 34 (FIG. 2). Thereby, the dispenser is low cost and is repositionable simply above the receptacles as a result of said rotation and as a result of said movement along the arm, without occupying too much laboratory bench space.
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公开(公告)号：US20210339209A1
公开(公告)日：2021-11-04
申请号：US17286834
申请日：2019-10-29
Applicant: Cytiva Sweden AB
Inventor： Mats Lundkvist
Abstract: The present disclosure relates to a mixing device (9) comprising an inlet channel (25), an outlet channel (27), a mixing cavity (29) and a laminar mixing element (31) arranged within the mixing cavity. The inlet channel extends along an axis (21) of the mixing device from a first end (23) of the mixing device to the mixing cavity. The outlet channel extends along the axis from the mixing cavity to a second end (24) of the mixing device arranged opposite to the first end. The mixing cavity is arranged between the inlet channel and the outlet channel and extends in an axial direction (A) along the axis and in a radial direction (R) outwardly from the axis to an outer wall (30) of the mixing cavity. The laminar mixing element extends radially across the mixing cavity, subdividing the mixing cavity into an inlet portion (26) and an outlet portion (28). The mixing element comprises a plurality of holes (41) extending through the mixing element. The said holes are distributed over the mixing element.
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公开(公告)号：US20240369472A1
公开(公告)日：2024-11-07
申请号：US18775959
申请日：2024-07-17
Applicant: Cytiva Sweden AB
Inventor： Hanno Ehring , Mats Lundkvist , David Carl Martin Bergman , Andreas Marcstrom
Abstract: The invention relates to an optical flow cell comprising a housing forming an enclosed and elongated fluid channel arranged along a first axis, an inlet arranged to connect a first outer surface area of the housing to a first end of the fluid channel and an outlet arranged to connect a second outer surface area to a second end of the fluid channel, a first light guide and a second light guide concentrically arranged along a second axis and on opposite side walls of the fluid channel. The invention further relates to a corresponding method to produce an optical flow cell.
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Patent Agency Ranking
公开(公告)号：US20240017252A1
公开(公告)日：2024-01-18
申请号：US18475121
申请日：2023-09-26
Applicant: Cytiva Sweden AB
Inventor： Tuomo Valtteri Frigard , Robert Magnusson , Mats Lundkvist , Karl Axel Jakob Liderfelt , Helena Nordvarg , Andreas Torbjorn Lundin , Peter Arne Reffner
CPC classification number: B01L3/502715 , B01D15/10 , B01D61/145 , B01L3/502738 , B01L3/502761 , B01D2311/2626 , B01D2315/16 , B01L2200/028 , B01L2200/0647 , B01L2300/0627 , B01L2300/0809 , B01L2300/0864 , B01L2400/06
Abstract: Disclosed is a modular bio-processing unit comprising: a housing having one or more internal fluid paths, the housing having at least one inlet and at least one outlet, each in fluid communication with the fluid path or one or more of the fluid paths; one or more sensor elements operatively associated with the or each path, said sensor(s) elements including elements of one or more of: a flow sensor, a flow rate sensor, a conductivity sensor, a pressure sensor, a pH sensor, and a light absorbance sensor such as a UV spectroscopic concentration sensor; one or more fluid flow inducing components operatively associated with the or each fluid path; and plural valves for preventing or reducing flow in the or each path, the housing, inlet(s), outlet(s), flow inducing component(s) and valve(s) being arranged to operate together as a bio-processing unit within or substantially within the housing.
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公开(公告)号：US11333641B2
公开(公告)日：2022-05-17
申请号：US16070846
申请日：2017-01-27
Applicant: Cytiva Sweden AB
Inventor： Stefan Dargy , Olle Bjernulf , Mats Lundkvist
Abstract: Disclosed is a fraction collector for dispensing liquids into plural receptacles (P1,P2) arranged in a two dimensional array. The fraction collector comprises a table (22) for supporting said receptacles, and an arm supported above the table, in turn supporting a liquid dispenser (35), the fraction collector arm is rotatable about an arm axis (C) and the liquid dispenser is movable along the arm on a carriage 34 (FIG. 2). Thereby, the dispenser is low cost and is repositionable simply above the receptacles as a result of said rotation and as a result of said movement along the arm, without occupying too much laboratory bench space.
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公开(公告)号：US20220018817A1
公开(公告)日：2022-01-20
申请号：US17294710
申请日：2019-12-04
Applicant: Cytiva Sweden AB
Inventor： Daniel Salomonsson , Mats Lundkvist
Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.
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公开(公告)号：US20240361282A1
公开(公告)日：2024-10-31
申请号：US18770467
申请日：2024-07-11
Applicant: Cytiva Sweden AB
Inventor： Daniel Salomonsson , Mats Lundkvist
CPC classification number: G01N30/6082 , B01D15/206 , B01D15/22
Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.
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公开(公告)号：US12066375B2
公开(公告)日：2024-08-20
申请号：US16464759
申请日：2017-11-30
Applicant: Cytiva Sweden AB
Inventor： Hanno Ehring , Mats Lundkvist , David Carl Martin Bergman , Andreas Marcstrom
CPC classification number: G01N21/05 , G01N21/03 , G01N21/0303 , G01N21/85 , G01N2201/0668 , G01N2201/08
Abstract: The invention relates to an optical flow cell comprising a housing forming an enclosed and elongated fluid channel arranged along a first axis, an inlet arranged to connect a first outer surface area of the housing to a first end of the fluid channel and an outlet arranged to connect a second outer surface area to a second end of the fluid channel, a first light guide and a second light guide concentrically arranged along a second axis and on opposite side walls of the fluid channel. The invention further relates to a corresponding method to produce an optical flow cell.
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