公开(公告)号：US20030152969A1

公开(公告)日：2003-08-14

申请号：US10289141

申请日：2002-11-05

Applicant: California Institute of Technology

Inventor： Stephen R. Quake ,  R. Michael van Dam ,  James P. Brody ,  Rebecca Shafee

IPC: C12Q001/68 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50

CPC classification number: G06F19/20 ,  G06F17/15 ,  G06F19/24

Abstract: Techniques for processing gene expression data and predicting gene relationships are provided. More specifically, a method for processing gene expression ratios may include discretizing a first expression ratio for a first gene and a second expression ratio for a second gene for each of a plurality of experiments into one of three indications, calculating the probability that the combination of the discretized expression ratios for each of the plurality of experiments arises by random chance, and determining whether the first gene and the second gene are related.

Abstract translation: 提供了处理基因表达数据和预测基因关系的技术。 更具体地，用于处理基因表达比率的方法可以包括将用于第一基因的第一表达比例和第二基因的第二表达比例分离为多个实验中的每一个进行三个指示之一，计算组合 多个实验中的每一个的离散化表达比均由随机机会产生，并且确定第一基因和第二基因是否相关。