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公开(公告)号：US20190317311A1
公开(公告)日：2019-10-17
申请号：US16242934
申请日：2019-01-08
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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公开(公告)号：US10222605B2
公开(公告)日：2019-03-05
申请号：US15636494
申请日：2017-06-28
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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公开(公告)号：US09829695B2
公开(公告)日：2017-11-28
申请号：US15007196
申请日：2016-01-26
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
CPC classification number: G02B21/365 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6478 , G01N2201/0446 , G02B13/0095 , G02B21/0076 , G02B21/16 , G02B21/367 , H04N5/22541 , H04N5/2256 , H04N5/2258
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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公开(公告)号：US20160216208A1
公开(公告)日：2016-07-28
申请号：US15007159
申请日：2016-01-26
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
IPC: G01N21/64
CPC classification number: G02B21/365 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6478 , G01N2201/0446 , G02B13/0095 , G02B21/0076 , G02B21/16 , G02B21/367 , H04N5/22541 , H04N5/2256 , H04N5/2258
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
Abstract translation: 某些方面涉及多孔系统，装置和傅里叶片状和荧光成像的方法。
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公开(公告)号：US20160216503A1
公开(公告)日：2016-07-28
申请号：US15007196
申请日：2016-01-26
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
CPC classification number: G02B21/365 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6478 , G01N2201/0446 , G02B13/0095 , G02B21/0076 , G02B21/16 , G02B21/367 , H04N5/22541 , H04N5/2256 , H04N5/2258
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
Abstract translation: 在一个方面，成像系统包括：包括光源阵列的照明系统; 包括一个或多个透镜阵列的光学系统，每个透镜阵列包括透镜阵列，所述一个或多个透镜阵列中的每一个中的每个透镜与所述光源阵列的相应组的光源对准; 一种成像系统，包括图像传感器阵列，每个图像传感器与一个或多个透镜阵列的对应透镜或透镜组对准，每个图像传感器被配置为基于从所述一个或多个透镜阵列接收的光获取图像数据 相应的镜头或镜片组; 板接收器系统，其能够接收包括孔阵列的多孔板，所述板接收器系统被配置为使每个所述孔与所述图像传感器中的相应一个对准; 以及控制器，其被配置为控制所述光源的照明和由所述图像传感器获取图像数据，所述控制器还被配置为执行：包括多个扫描的图像获取处理，每个扫描与唯一的照明模式相关联， 每个图像传感器被配置为在每次扫描期间为相应的一个孔产生图像; 以及图像重建过程，在该图像重建过程期间，控制器基于在每个扫描期间针对相应的阱捕获的图像数据执行傅立叶ptychographic操作以生成每个孔的重建图像。
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Patent Agency Ranking
公开(公告)号：US10754138B2
公开(公告)日：2020-08-25
申请号：US16162271
申请日：2018-10-16
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
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公开(公告)号：US20190049712A1
公开(公告)日：2019-02-14
申请号：US16162271
申请日：2018-10-16
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
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公开(公告)号：US10168525B2
公开(公告)日：2019-01-01
申请号：US15007159
申请日：2016-01-26
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
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公开(公告)号：US20170299854A1
公开(公告)日：2017-10-19
申请号：US15636494
申请日：2017-06-28
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
CPC classification number: G02B21/365 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6478 , G01N2201/0446 , G02B13/0095 , G02B21/0076 , G02B21/16 , G02B21/367 , H04N5/22541 , H04N5/2256 , H04N5/2258
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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公开(公告)号：US10732396B2
公开(公告)日：2020-08-04
申请号：US16242934
申请日：2019-01-08
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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