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公开(公告)号：US20190240160A1
公开(公告)日：2019-08-08
申请号：US16318652
申请日：2017-07-20
Applicant: Capsugel Belgium NV
Inventor： Xiongwei David He , Stefaan Jaak Vanquickenborne , Jonathan Leonard Cape , Dwayne Thomas Friesen
CPC classification number: A61K9/4816 , A61J3/07 , A61K9/4808 , A61K9/4833 , A61K31/167 , B29C41/003 , B29C41/14 , B29C41/46 , B29K2105/0073 , B29L2031/7174
Abstract: An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.
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公开(公告)号：US20210220285A1
公开(公告)日：2021-07-22
申请号：US17224550
申请日：2021-04-07
Applicant: Capsugel Belgium NV
Inventor： Xiongwei David He , Stefaan Jaak Vanquickenborne , Jonathan Leonard Cape , Dwayne Thomas Friesen
Abstract: An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.
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Patent Agency Ranking
公开(公告)号：US20170231918A1
公开(公告)日：2017-08-17
申请号：US15587169
申请日：2017-05-04
Applicant: Capsugel Belgium NV
Inventor： Dominique Nicolas Cade , Xiongwei David He
CPC classification number: A61K9/4816 , A61K9/4825 , A61K9/4833 , A61K9/4866 , B29C41/003 , B29C41/14 , B29D22/00 , B29K2001/12 , B29K2003/00 , B29K2005/00 , B29K2089/00 , B29L2031/7174
Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.
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公开(公告)号：US10231934B2
公开(公告)日：2019-03-19
申请号：US15587169
申请日：2017-05-04
Applicant: Capsugel Belgium NV
Inventor： Dominique Nicolas Cade , Xiongwei David He
Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.
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公开(公告)号：US09700517B2
公开(公告)日：2017-07-11
申请号：US14470442
申请日：2014-08-27
Applicant: Capsugel Belgium NV
Inventor： Dominique Nicolas Cade , Xiongwei David He
CPC classification number: A61K9/4816 , A61K9/4825 , A61K9/4833 , A61K9/4866 , B29C41/003 , B29C41/14 , B29D22/00 , B29K2001/12 , B29K2003/00 , B29K2005/00 , B29K2089/00 , B29L2031/7174
Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.
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公开(公告)号：US20190175514A1
公开(公告)日：2019-06-13
申请号：US16281817
申请日：2019-02-21
Applicant: Capsugel Belgium NV
Inventor： Dominique Nicolas Cade , Xiongwei David He
Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.
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公开(公告)号：US20150050334A1
公开(公告)日：2015-02-19
申请号：US14470442
申请日：2014-08-27
Applicant: Capsugel Belgium NV
Inventor： Dominique Nicolas Cade , Xiongwei David He
CPC classification number: A61K9/4816 , A61K9/4825 , A61K9/4833 , A61K9/4866 , B29C41/003 , B29C41/14 , B29D22/00 , B29K2001/12 , B29K2003/00 , B29K2005/00 , B29K2089/00 , B29L2031/7174
Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.
Abstract translation: 本发明涉及新的耐酸硬性药物胶囊，其制造和使用这种胶囊的方法，特别地但不仅限于口服给予人或动物的药物，兽医产品，食物和膳食补充剂。 本发明的胶囊是通过含水组合物获得的，该组合物包含水溶性成膜聚合物和结冷胶，其重量比为4至15重量份的结冷胶，用于100重量份成膜聚合物。
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