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公开(公告)号：USRE45575E1
公开(公告)日：2015-06-23
申请号：US13932475
申请日：2013-07-01
发明人： Helmut Lippert , Matthias Wald , Benno Radt
CPC分类号： G02B21/06 , G02B21/0032 , G02B21/0076
摘要： The invention is directed to an optical arrangement with a light source for emitting a light bundle and with optical elements for transforming this light bundle into the shape of a light sheet, particularly suitable for illuminating individual planes of a three-dimensional specimen in selective plane illumination microscopy (SPIM). According to the invention, means are provided for varying the cross section of the light sheet, for varying the length of the light sheet and/or for influencing the direction in which individual beam components extending within the light sheet are directed to the specimen substance. This makes it possible to adapt the geometry of the light sheet to the illumination requirements for observing one and the same specimen plane with a plurality of different objectives and, if required, to reduce shadows occurring within the observed specimen plane as a result of the illumination.
摘要翻译： 本发明涉及一种光学装置，其具有用于发射光束的光源和用于将该光束变换为光片的形状的光学元件，特别适用于在选择性平面照明中照射三维样本的各个平面 显微镜（SPIM）。 根据本发明，提供了用于改变光片的横截面的装置，用于改变光片的长度和/或用于影响在光片内延伸的各个光束分量被引导到样本物质的方向。 这使得可以使光片的几何尺寸适应于用于观察具有多个不同物镜的同一样本平面的照明要求，并且如果需要，可以减少作为照明的结果在观察到的样本平面内发生的阴影 。
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公开(公告)号：US09733160B2
公开(公告)日：2017-08-15
申请号：US14132988
申请日：2013-12-18
发明人： Wibke Hellmich , Benno Radt , Helmut Lippert , Olaf Selchow , Uwe Wolf , Juergen Haese
摘要： The invention is directed to method for positioning and aligning a preferably biological sample in the detection area of the objective of a microscope arrangement. According to the invention, the method mentioned above has the following method steps: a sample is introduced into a transparent medium, preferably agarose gel, which is initially liquid; the medium is changed from the liquid state to the solid state, wherein the sample is fixated within the medium, but the transparency of the medium is retained; the solidified medium is positioned in the microscope arrangement in such a way that the sample enclosed therein is situated in the detection area of the objective. Further, a device is proposed for positioning and aligning a preferably biological sample in the detection area of the objective of a microscope arrangement.
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3.发明申请公开(公告)号：US20140313311A1
公开(公告)日：2014-10-23
申请号：US14254070
申请日：2014-04-16
发明人： Wolf JOCKUSCH , Robert Schrem , Peter Weber , Alexander GAIDUK , Dominik Stehr , Benno Radt , Markus Gnauck
CPC分类号： G02B21/365 , G02B21/24 , H04N5/23216
摘要： The invention relates to a control device and to a method for controlling a motorized digital microscope. The control device comprises at least one first module (01) for controlling the hardware, the software and the work flow of the digital microscope during the examination of a specimen. According to the invention, the first module (01) comprises a first input means (02, 16) having force feedback for controlling functions of the digital microscope. In a method according to the invention, data input takes place via a first input means, wherein force feedback is generated via the success or progression of the input.
摘要翻译： 本发明涉及一种控制装置和一种用于控制电动数字显微镜的方法。 所述控制装置包括用于在检查样本期间控制数字显微镜的硬件，软件和工作流程的至少一个第一模块（01）。 根据本发明，第一模块（01）包括具有用于控制数字显微镜的功能的力反馈的第一输入装置（02,16）。 在根据本发明的方法中，经由第一输入装置进行数据输入，其中通过输入的成功或进行产生力反馈。
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公开(公告)号：US10018823B2
公开(公告)日：2018-07-10
申请号：US14254070
申请日：2014-04-16
发明人： Wolf Jockusch , Robert Schrem , Peter Weber , Alexander Gaiduk , Dominik Stehr , Benno Radt , Markus Gnauck
CPC分类号： G02B21/365 , G02B21/24 , H04N5/23216
摘要： The invention relates to a control device and to a method for controlling a motorized digital microscope. The control device comprises at least one first module (01) for controlling the hardware, the software and the work flow of the digital microscope during the examination of a specimen. According to the invention, the first module (01) comprises a first input means (02, 16) having force feedback for controlling functions of the digital microscope. In a method according to the invention, data input takes place via a first input means, wherein force feedback is generated via the success or progression of the input.
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5.外观设计Combined touchpad, operating knobs and display module for electrical control device 有权组合触摸板，操作旋钮和电气控制装置的显示模块公开(公告)号：USD777118S1
公开(公告)日：2017-01-24
申请号：US29492821
申请日：2014-06-03
设计人： Alexander Gaiduk , Wolf Jockusch , Dominik Stehr , Robert Schrem , Peter Weber , Benno Radt
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6.发明申请DIGITAL MICROSCOPE AND METHOD FOR OPTIMIZING THE WORK PROCESS IN A DIGITAL MICROSCOPE 审中-公开用于优化数字显微镜中的工作过程的数字显微镜和方法公开(公告)号：US20140313312A1
公开(公告)日：2014-10-23
申请号：US14255914
申请日：2014-04-17
发明人： Alexander GAIDUK , Dominik Stehr , Benno Radt , Wolf Jockusch , Enrico Geissler , Johannes Winterot , Markus Gnauck , Johannes Knoblich , Max Funck
CPC分类号： H04N5/23209 , G02B21/24 , G02B21/365
摘要： The invention relates to a digital microscope and to a method for optimizing a work process in such a digital microscope. The digital microscope comprises according to the invention at least one first monitoring sensor for observing a sample (08), a sample table (4), an optics unit (02) or a user, and a monitoring unit. In the method according to the invention, first operating data of the first operating sensor are acquired and analyzed and evaluated in an automated manner in the monitoring unit, in order to generate control data and to use said data for controlling the work process of the digital microscope.
摘要翻译： 本发明涉及一种数字显微镜和一种在这种数字显微镜中优化工作过程的方法。 数字显微镜包括根据本发明的用于观察样品（08），样品台（4），光学单元（02）或用户和监测单元的至少一个第一监测传感器。 在根据本发明的方法中，在监控单元中以自动的方式获取并分析和评估第一操作传感器的第一操作数据，以便产生控制数据并使用所述数据来控制数字的工作过程 显微镜。
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