公开(公告)号：US07060047B2

公开(公告)日：2006-06-13

申请号：US10344721

申请日：2002-05-30

申请人： Carlo Alberto Lodi ,  Francesco Paolini ,  Enrico Canini

发明人： Carlo Alberto Lodi ,  Francesco Paolini ,  Enrico Canini

IPC分类号： A61M37/00 ,  C02F1/44

CPC分类号： A61M1/367 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3656 ,  A61M1/3669 ,  A61M5/16831 ,  A61M2039/1005 ,  A61M2205/12

摘要： A method of sensing the detachment of the venous needle (13) from a patient (P) during an extracorporeal blood treatment in a dialysis machine (1) having an extracorporeal blood circuit (2), in which an electric current is made to flow along a closed-loop path (P1) of an electrical circuit (37) formed by an electrical line (21, 22, 23) external to the extracorporeal circuit (2), a portion of extracorporeal circuit (2) directly connected to the venous needle (13), and the patient (P); a signal correlated with the electric current along the electrical line (21, 22, 23) is detected; and the signal is compared with a threshold value by means of a control unit (15).

摘要翻译： 一种在具有体外血液循环（2）的透析机（1）中感测在体外血液处理期间从患者（P）脱离静脉针（13）的方法，其中使电流流动 由体外电路（2）外部的电线（21,22,23）形成的电路（37）的闭环路径（P1），直接连接到静脉的体外电路（2）的一部分 针（13）和患者（P）; 检测与沿着电线（21,22,23）的电流相关的信号; 并且通过控制单元（15）将信号与阈值进行比较。

公开(公告)号：US06537240B2

公开(公告)日：2003-03-25

申请号：US09091349

申请日：1999-05-03

申请人： Giovanni Cavicchioli ,  Enrico Canini ,  Massimo Fava

发明人： Giovanni Cavicchioli ,  Enrico Canini ,  Massimo Fava

IPC分类号： A61M3700

CPC分类号： A61M1/3621 ,  A61M1/16 ,  A61M1/3609 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M2202/0433 ,  A61M2205/3368 ,  A61M2205/52 ,  A61M2230/65

摘要： In an extracorporeal blood treatment system, non-treated blood may be withdrawn from a patient through an arterial line connected to a first compartment of a blood treatment apparatus. The blood treatment apparatus also includes a second compartment separated from the first component by a semi-permeable membrane. Treated blood may be returned to the patient through a venous line connected to the second compartment. In order to determine blood recirculation, i.e., a mixture of treated blood and non-treated blood in the arterial line, the ultrafiltration rate of plasma water through the semi permeable membrane of the treatment apparatus may be temporarily increased or decreased, and the resulting variation of the blood concentration, i.e., of the ratio of the volume of the plasma volume to the blood volume, is determined. The extent of the mixture of the treated blood and the non-treated blood in the arterial line may then be calculated as a function of the blood flow rate in the treatment apparatus, of the amplitude of the variation of the ultrafiltration rate, and of at least two values of the blood concentration, determined before and during the variation of the ultrafiltration flow rate, respectively.

摘要翻译： 在体外血液处理系统中，未经处理的血液可以通过连接到血液处理设备的第一隔室的动脉管线从患者体内取出。 血液处理装置还包括通过半透膜与第一部件分离的第二室。 治疗的血液可以通过连接到第二隔室的静脉管线返回到患者。 为了确定血液循环，即动脉管线中的处理血液和未处理血液的混合物，通过治疗装置的半透膜的血浆超滤速率可以暂时增加或减少，并且所得到的变化 的血液浓度，即等离子体体积与血液体积的比率的比例。 然后可以将处理的血液和未处理的血液在动脉线中的混合物的程度作为治疗装置中的血液流量的函数，超滤率的变化幅度和 分别在超滤流量变化之前和期间测定血液浓度的至少两个值。

公开(公告)号：US06932786B2

公开(公告)日：2005-08-23

申请号：US09914348

申请日：2000-12-22

申请人： Sara Giacomelli ,  Ivan Rossi ,  Enrico Canini

发明人： Sara Giacomelli ,  Ivan Rossi ,  Enrico Canini

IPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/36 ,  A61M37/00 ,  C02F1/44

CPC分类号： A61M1/3669 ,  A61M1/16 ,  A61M1/3656 ,  A61M1/367 ,  A61M2205/13 ,  A61M2205/50

摘要： A device for monitoring the access to the cardiovascular system of a patient undergoing an extracorporeal treatment of blood in a machine (1) comprising a treatment device (4) and an extracorporeal circuit (2), comprises: a voltage generator (16) for generating a potential difference between a part of the machine (1) and a first point (B) of a venous branch (8) of the extracorporeal circuit (2), connecting the patient to the treatment device (4); a detector (17) for detecting the value (dV) of a quantity that correlates with the electric current along at least one section (10a; 10b; 10c) of the venous branch (10) between the first point (B) and a venous needle (13) fitted at the end of the venous branch (8) and inserted in the vascular system of the patient (P); calculating means (15) for comparing the detected value (dV) with a reference range (I).

摘要翻译： 一种用于监测在包括治疗装置（4）和体外电路（2）的机器（1）中进行血液体外处理的患者的心血管系统的通路的装置，包括：电压发生器（16），用于产生 所述机器（1）的一部分与所述体外回路（2）的静脉分支（8）的第一点（B）之间的电位差，将所述患者连接到所述治疗装置（4）; 检测器（17），用于检测与第一点（B）之间的静脉分支（10）的至少一个部分（10a; 10b; 10c）的电流相关的量的值（dV） 以及安装在静脉分支（8）的端部并插入患者（P）的血管系统中的静脉针（13）; 用于将检测值（dV）与参考范围（I）进行比较的计算装置（15）。