公开(公告)号：US20060029578A1

公开(公告)日：2006-02-09

申请号：US11031325

申请日：2005-01-07

申请人： Caroline Hoemann ,  Michael Buschmann ,  Marc Mckee

发明人： Caroline Hoemann ,  Michael Buschmann ,  Marc Mckee

IPC分类号： A61K38/17 ,  A61K31/737 ,  A61K31/727

CPC分类号： A61L27/3804 ,  A61K9/0019 ,  A61K9/0024 ,  A61K9/06 ,  A61K31/727 ,  A61K31/728 ,  A61K31/737 ,  A61K35/15 ,  A61K35/16 ,  A61K35/18 ,  A61K35/19 ,  A61K38/363 ,  A61K38/4833 ,  A61K38/4846 ,  A61K47/10 ,  A61K47/36 ,  A61L27/18 ,  A61L27/20 ,  A61L27/22 ,  A61L27/3616 ,  A61L27/3641 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/3839 ,  A61L27/50 ,  A61K2300/00

摘要： The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected tumors, and ulcers. The method comprises the step of introducing into the tissue a temperature-dependent polymer gel composition such that the composition adhere to the tissue and promote support for cell proliferation for repairing the tissue. Other than a polymer, the composition preferably comprises a blood component such as whole blood, processed blood, venous blood, arterial blood, blood from bone, blood from bone-marrow, bone marrow, umbilical cord blood, placenta blood, erythrocytes, leukocytes, monocytes, platelets, fibrinogen, thrombin and platelet rich plasma. The present invention also relates to a new composition to be used with the method of the present invention.