公开(公告)号：US10301637B2

公开(公告)日：2019-05-28

申请号：US14744386

申请日：2015-06-19

Applicant: CELLECTIS

Inventor： Benjamin Clasen ,  Daniel F. Voytas ,  Feng Zhang

IPC: C12N15/82 ,  C08B30/04

Abstract: Materials and methods for making plants (e.g., Solanum varieties) with decreased levels of amylose are provided herein. The methods can include making mutations in the gene encoding granule bound starch synthase (GBSS), where the mutations are induced using a rare-cutting endonuclease.

公开(公告)号：US20160037742A1

公开(公告)日：2016-02-11

申请号：US14653604

申请日：2013-12-20

Applicant: CELLECTIS

Inventor： Luc Mathis ,  Daniel F. Voytas ,  Feng Zhang ,  Benjamin Clasen ,  William Haun ,  Thomas Stoddard

IPC: A01H5/04 ,  A23L1/217

CPC classification number: C12N15/01 ,  A23V2002/00 ,  C12N15/8245

Abstract: Materials and methods are provided for making Solanum varieties with decreased accumulation of reducing sugars and acrylamide in cold-stored potatoes, specifically, by making TALE-nuclease-induced mutations in genes encoding vacuolar invertase.

Abstract translation: 提供了材料和方法，用于制备在冷藏土豆中还原糖和丙烯酰胺积累减少的茄属品种，特别是通过在编码液泡转化酶的基因中产生TALE-核酸酶诱导的突变。

公开(公告)号：US20200002709A1

公开(公告)日：2020-01-02

申请号：US16328323

申请日：2017-08-30

Applicant: CELLECTIS

Inventor： Song Luo ,  Benjamin Clasen ,  Feng Zhang ,  Nicholas J. Baltes ,  Javier Gil Humanes

IPC: C12N15/82

Abstract: Materials and methods are provided for making plants (e.g., soybean varieties, wheat varieties, or corn varieties) with altered amino acid content. For example, materials and methods are provided for making TALE nuclease-induced mutations in genes encoding seed storage proteins, or by making TALE nuclease-induced deletions of within seed storage protein genes.

公开(公告)号：US20190211349A1

公开(公告)日：2019-07-11

申请号：US16326549

申请日：2017-08-18

Applicant: CELLECTIS

Inventor： Benjamin Clasen ,  Song Luo ,  Daniel F. Voytas ,  Feng Zhang

IPC: C12N15/82 ,  C12N15/52

CPC classification number: C12N15/8261 ,  C12N9/0059 ,  C12N15/52 ,  C12N15/8242 ,  C12Y110/03001

Abstract: Materials and methods are provided for making plants (e.g., Solanum varieties) with resistance to black-spot bruising, specifically, by making TALE-nuclease-induced mutations in genes encoding tuber specific expressed polyphenol oxidase.

公开(公告)号：US10513698B2

公开(公告)日：2019-12-24

申请号：US14653604

申请日：2013-12-20

Applicant: CELLECTIS

Inventor： Luc Mathis ,  Daniel F. Voytas ,  Feng Zhang ,  Benjamin Clasen ,  William Haun ,  Thomas Stoddard

IPC: C12N15/01 ,  C12N15/82 ,  A01H6/82

Abstract: Materials and methods are provided for making Solanum varieties with decreased accumulation of reducing sugars and acrylamide in cold-stored potatoes, specifically, by making TALE-nuclease-induced mutations in genes encoding vacuolar invertase.

公开(公告)号：US20150368659A1

公开(公告)日：2015-12-24

申请号：US14744386

申请日：2015-06-19

Applicant: CELLECTIS

Inventor： Benjamin Clasen ,  Daniel F. Voytas ,  Feng Zhang

IPC: C12N15/82 ,  C08B30/04 ,  A01H5/04

CPC classification number: C12N15/8245 ,  C08B30/048 ,  C12N15/8213

Abstract: Materials and methods for making plants (e.g., Solanum varieties) with decreased levels of amylose are provided herein. The methods can include making mutations in the gene encoding granule bound starch synthase (GBSS), where the mutations are induced using a rare-cutting endonuclease.

Abstract translation: 本文提供了具有降低的直链淀粉含量的植物（例如茄属）的材料和方法。 该方法可以包括在编码颗粒结合淀粉合酶（GBSS）的基因中进行突变，其中使用稀有切割的内切核酸酶诱导突变。

公开(公告)号：US20200157525A1

公开(公告)日：2020-05-21

申请号：US16664245

申请日：2019-10-25

Applicant: CELLECTIS

Inventor： Luc Mathis ,  Daniel F. Voytas ,  Feng Zhang ,  Benjamin Clasen ,  William Haun ,  Thomas Stoddard

IPC: C12N15/01 ,  C12N15/82

Abstract: Materials and methods are provided for making plants (e.g., Solanum varieties) with decreased accumulation of reducing sugars and acrylamide in cold-stored potatoes, specifically, by making TALE-nuclease-induced mutations in genes encoding vacuolar invertase.

公开(公告)号：US20170258024A1

公开(公告)日：2017-09-14

申请号：US15334017

申请日：2016-10-25

Applicant: CELLECTIS

Inventor： Luc Mathis ,  Daniel F. Voytas ,  Feng Zhang ,  Benjamin Clasen ,  William Haun ,  Thomas Stoddard

IPC: A01H5/04 ,  C12N15/82 ,  C12N15/01

CPC classification number: C12N15/01 ,  A23V2002/00 ,  C12N15/8245

Abstract: Materials and methods are provided for making plants (e.g., Solanum varieties) with decreased accumulation of reducing sugars and acrylamide in cold-stored potatoes, specifically, by making TALE-nuclease-induced mutations in genes encoding vacuolar invertase.

公开(公告)号：US20140178561A1

公开(公告)日：2014-06-26

申请号：US14135766

申请日：2013-12-20

Applicant: Cellectis

Inventor： Luc Mathis ,  Daniel F. Voytas ,  Feng Zhang ,  Benjamin Clasen ,  William Haun ,  Thomas Stoddard

IPC: C12N15/01 ,  A23L1/217

CPC classification number: C12N15/01 ,  A23V2002/00 ,  C12N15/8245

Abstract: Materials and methods are provided for making plants (e.g., Solanum varieties) with decreased accumulation of reducing sugars and acrylamide in cold-stored potatoes, specifically, by making TALE-nuclease-induced mutations in genes encoding vacuolar invertase.

Abstract translation: 提供了材料和方法，用于制造冷藏土豆中还原糖和丙烯酰胺积累减少的植物（例如茄属品种），具体地，通过在编码液泡转化酶的基因中产生TALE-核酸酶诱导的突变。