专利检索 ap:("Cephalon, Inc.") AND inv:"Diane E. Gingrich" 第 1 页

1.

发明授权
Imidazo[4,5-b]pyridine derivatives as ALK and JAK modulators for the treatment of proliferative disorders 有权
标题翻译：咪唑并[4,5-b]吡啶衍生物作为ALK和JAK调节剂用于治疗增殖性疾病

公开(公告)号：US09238656B2

公开(公告)日：2016-01-19

申请号：US14446411

申请日：2014-07-30

申请人： Cephalon, Inc.

发明人： Henry J. Breslin , Matthew A. Curry , Diane E. Gingrich , Keith S. Learn , Gregory R. Ott , Jason C. Wagner

IPC分类号： C07D493/08 , C07D491/107 , C07D471/04 , A61K31/47 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P35/00

CPC分类号： C07D493/08 , C07D471/04 , C07D491/107

摘要： This application relates to compounds of the Formula I as defined herein, and/or salts thereof. This application further relates to compositions and methods of using these compounds and/or salts thereof. The compounds of Formula I are useful as ALK and JAK modulators for the treatment of proliferative disorders.

摘要翻译： 本申请涉及本文定义的式I化合物和/或其盐。本申请还涉及使用这些化合物和/或其盐的组合物和方法。式I的化合物可用作治疗增殖性疾病的ALK和JAK调节剂。

2.

发明申请
Preparation and Uses of 1,2,4-Triazolo [1,5a] Pyridine Derivatives 有权
标题翻译： 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途

公开(公告)号：US20130296312A1

公开(公告)日：2013-11-07

申请号：US13920153

申请日：2013-06-18

申请人： Cephalon, Inc.

发明人： Matthew A. Curry , Bruce D. Dorsey , Benjamin J. Dugan , Diane E. Gingrich , Eugen F. Mesaros , Karen L. Milkiewicz

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： This application relates, in part, to compounds of the general Formula I and/or salts thereof, wherein X, R1A, R1B, R2, R3, R4, and R5 are as defined herein. The application also relates to compositions and methods of inhibiting at least JAK2 in subjects in recognized need thereof for the treatment of diseases or disorders for which inhibition of at least JAK2 is indicated.

摘要翻译： 本申请部分涉及通式I和/或其盐的化合物，其中X，R 1A，R 1B，R 2，R 3，R 4和R 5如本文所定义。本申请还涉及在认可需要的受试者中至少抑制JAK2以治疗至少表达JAK2的抑制的疾病或病症的组合物和方法。

3.

发明申请
Imidazo[4,5-b]pyridine Derivatives as ALK and JAK Modulators for the Treatment of Proliferative Disorders 有权
标题翻译：咪唑并[4,5-b]吡啶衍生物作为ALK和JAK调节剂治疗增殖性疾病

公开(公告)号：US20140350011A1

公开(公告)日：2014-11-27

申请号：US14446411

申请日：2014-07-30

申请人： Cephalon, Inc.

发明人： Henry J. Breslin , Matthew A. Curry , Diane E. Gingrich , Keith S. Learn , Gregory R. Ott , Jason C. Wagner

IPC分类号： C07D493/08 , C07D491/107 , C07D471/04

CPC分类号： C07D493/08 , C07D471/04 , C07D491/107

摘要： This application relates to compounds of the Formula I as defined herein, and/or salts thereof. This application further relates to compositions and methods of using these compounds and/or salts thereof. The compounds of Formula I are useful as ALK and JAK modulators for the treatment of proliferative disorders.

摘要翻译： 本申请涉及本文定义的式I化合物和/或其盐。本申请还涉及使用这些化合物和/或其盐的组合物和方法。式I的化合物可用作治疗增殖性疾病的ALK和JAK调节剂。

4.

发明授权
Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives 有权
标题翻译： 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途

公开(公告)号：US08633173B2

公开(公告)日：2014-01-21

申请号：US13920153

申请日：2013-06-18

申请人： Cephalon, Inc.

发明人： Matthew A. Curry , Bruce D. Dorsey , Benjamin J. Dugan , Diane E. Gingrich , Eugen F. Mesaros , Karen L. Milkiewicz

IPC分类号： A61K31/675 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/55

CPC分类号： C07D471/04

摘要： This application relates, in part, to compounds of the general Formula I and/or salts thereof, wherein X, R1A, R1B, R2, R3, R4, and R5 are as defined herein. The application also relates to compositions and methods of inhibiting at least JAK2 in subjects in recognized need thereof for the treatment of diseases or disorders for which inhibition of at least JAK2 is indicated.

摘要翻译： 本申请部分涉及通式I和/或其盐的化合物，其中X，R 1A，R 1B，R 2，R 3，R 4和R 5如本文所定义。本申请还涉及在认可需要的受试者中至少抑制JAK2以治疗至少表达JAK2的抑制的疾病或病症的组合物和方法。