-
公开(公告)号:US07579160B2
公开(公告)日:2009-08-25
申请号:US10922124
申请日:2004-08-19
CPC分类号: G01N33/57411 , A61K39/00 , A61K39/0011 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , A61K2039/545 , C07K14/47 , C07K14/4748 , C07K16/3023 , C07K2317/21 , C07K2317/34 , C07K2317/73 , C07K2319/00 , C07K2319/21 , C07K2319/40 , C12N15/86 , C12N2710/10343 , C12N2710/10371 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/5088 , G01N33/57423
摘要: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
摘要翻译: 公开了用于治疗和诊断癌症,特别是肺癌的组合物和方法。 说明性组合物包含一种或多种肺肿瘤多肽,其免疫原性部分,编码这种多肽的多核苷酸,表达此类多肽的抗原呈递细胞,以及对表达该多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病,特别是肺癌的诊断,预防和/或治疗。