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    METHOD FOR MASS PRODUCTION OF FACTOR VII/VIIA
    1.
    发明申请
    METHOD FOR MASS PRODUCTION OF FACTOR VII/VIIA 有权
    大量生产VII / VIIA因子的方法

    公开(公告)号：US20130273634A1

    公开(公告)日：2013-10-17

    申请号：US13881974

    申请日：2011-10-26

    申请人： Chang Hwan Kim ,  Sung Kap Hong ,  Byung Sun Lee ,  Sung Hwan Hong ,  Se Chang Kwon

    发明人： Chang Hwan Kim ,  Sung Kap Hong ,  Byung Sun Lee ,  Sung Hwan Hong ,  Se Chang Kwon

    IPC分类号： C12N9/64

    CPC分类号： C12N9/6437 ,  C07K14/745 ,  C12N15/85 ,  C12N2830/85

    摘要： A method for the mass production of human coagulation factor VII. The method includes a) providing an expression vector carrying i) a dihydrofolate reductase promoter devoid of one or more CCGCC repeat sequences from the GC-rich region thereof and a dihydrofolate reductase (DHFR) gene operably linked thereto and ii) a cytomegalovirus (CMV) promoter and a human coagulation factor VII gene operably linked thereto; b) obtaining a transformed a host cell line containing the expression vector; and c) culturing the transfected host cell in the presence of a dihydrofolate reductase inhibitor to select cells which express human coagulation factor VII with high efficiency; and d) adding sodium butyrate to the selected host cells.

    摘要翻译： 大量生产人凝血因子VII的方法。 所述方法包括：a）提供表达载体，其携带i）没有来自其富含GC的区域的一个或多个CCGCC重复序列的二氢叶酸还原酶启动子和与其可操作地连接的二氢叶酸还原酶（DHFR）基因，和ii）巨细胞病毒（CMV） 启动子和与之有效连接的人凝血因子VII基因; b）获得含有表达载体的转化的宿主细胞系; 和c）在二氢叶酸还原酶抑制剂存在下培养转染的宿主细胞以选择以高效率表达人凝血因子VII的细胞; 和d）向所选择的宿主细胞中加入丁酸钠。

    Method for mass production of factor VII/VIIA
    2.
    发明授权
    Method for mass production of factor VII/VIIA 有权
    大量生产因子VII / VIIA的方法

    公开(公告)号：US09243237B2

    公开(公告)日：2016-01-26

    申请号：US13881974

    申请日：2011-10-26

    申请人： Chang Hwan Kim ,  Sung Kap Hong ,  Byung Sun Lee ,  Sung Hwan Hong ,  Se Chang Kwon

    发明人： Chang Hwan Kim ,  Sung Kap Hong ,  Byung Sun Lee ,  Sung Hwan Hong ,  Se Chang Kwon

    IPC分类号： A61K38/00 ,  C12N9/64 ,  C07K14/745

    CPC分类号： C12N9/6437 ,  C07K14/745 ,  C12N15/85 ,  C12N2830/85

    摘要： A method for the mass production of human coagulation Factor VII. The method includes a) providing an expression vector carrying i) a dihydrofolate reductase promoter devoid of one or more CCGCC repeat sequences from the GC-rich region thereof and a dihydrofolate reductase (DHFR) gene operably linked thereto and ii) a cytomegalovirus (CMV) promoter and a human coagulation Factor VII gene operably linked thereto; b) obtaining a transformed host cell line containing the expression vector; and c) culturing the transfected host cell in the presence of a dihydrofolate reductase inhibitor to select cells which express human coagulation Factor VII with high efficiency; and d) adding sodium butyrate to the selected host cells.

    摘要翻译： 大量生产人凝血因子VII的方法。 所述方法包括：a）提供表达载体，其携带i）没有来自其富含GC的区域的一个或多个CCGCC重复序列的二氢叶酸还原酶启动子和与其可操作地连接的二氢叶酸还原酶（DHFR）基因，和ii）巨细胞病毒（CMV） 启动子和与之有效连接的人凝血因子VII基因; b）获得含有表达载体的转化的宿主细胞系; 和c）在二氢叶酸还原酶抑制剂存在下培养转染的宿主细胞以选择以高效率表达人凝血因子VII的细胞; 和d）向所选择的宿主细胞中加入丁酸钠。

    Rotary head drum with integrated yoke and vibration resistant base
    4.
    发明授权
    Rotary head drum with integrated yoke and vibration resistant base 失效
    旋转磁头鼓带有集成磁轭和抗振基座

    公开(公告)号：US5729407A

    公开(公告)日：1998-03-17

    申请号：US621322

    申请日：1996-03-25

    申请人： Young Gil Koh ,  Sung Hwan Hong ,  Yong Chai Choi

    发明人： Young Gil Koh ,  Sung Hwan Hong ,  Yong Chai Choi

    IPC分类号： G11B5/52 ,  G11B5/53 ,  G11B21/04

    CPC分类号： G11B5/53 ,  G11B21/04

    摘要： A rotary head drum of a magnetic recording/playback apparatus having a back yoke integrated with a ring collar. The head drum includes a rotatable shaft, an upper rotary drum and a lower stationary drum which are mounted on upper and lower parts of the rotatable shaft, respectively. The back yoke integrated with the ring collar is mounted about the rotatable shaft under the lower stationary drum. The ring collar maintains a predetermined gap between a motor stator and a motor rotor. The motor stator is mounted about the rotatable shaft under the back yoke and the motor rotor is mounted on a lower surface of the ring collar. The motor housing is mounted on a lower surface of the lower stationary drum and made of a plastic material for absorbing a vibration.

    摘要翻译： 一种磁记录/重放装置的旋转磁头鼓，其具有与环形套环一体的背轭。 头鼓包括分别安装在可旋转轴的上部和下部上的可旋转轴，上旋转滚筒和下固定滚筒。 与环形圈一体化的后轭在下固定鼓下方围绕可旋转轴安装。 环形套环在电动机定子和电动机转子之间保持预定的间隙。 电动机定子围绕后轭的可旋转轴安装，并且电动机转子安装在环形套环的下表面上。 电动机壳体安装在下固定鼓的下表面上，并由用于吸收振动的塑料材料制成。

    Slant post base mounting mechanism for a magnetic recording and reproducing apparatus
    5.
    发明授权
    Slant post base mounting mechanism for a magnetic recording and reproducing apparatus 失效
    用于磁记录和再现装置的倾斜柱基安装机构

    公开(公告)号：US5640287A

    公开(公告)日：1997-06-17

    申请号：US438547

    申请日：1995-05-10

    申请人： Haksun Hwang ,  Ingi Cheon ,  Sang Jig Lee ,  Pohyoung Koh ,  Hyeoksoo Park ,  Sungwoo Choi ,  Sung Hwan Hong

    发明人： Haksun Hwang ,  Ingi Cheon ,  Sang Jig Lee ,  Pohyoung Koh ,  Hyeoksoo Park ,  Sungwoo Choi ,  Sung Hwan Hong

    IPC分类号： G11B15/665 ,  G11B15/61

    CPC分类号： G11B15/6653

    摘要： A slant post base mounting mechanism for a magnetic recording and reproducing apparatus includes a support for preventing movement of an adjusting screw, the support having an elastic member mounted on upper surface thereof and a plate spring formed with a clamp shaped, a v-type stopper having holes formed on an upper and a vertical surfaces thereof, respectively. Also, the plate spring includes a guide portion formed on a lower surface thereof, the guide portion being in contact with the protrusion of the slant post base in order to support the adjusting screw, and a slant portion formed at an end of the guide portion, the slant portion being movably inserted in a hole formed at a vertical surface of the V-type stopper.

    摘要翻译： 用于磁记录和再现装置的倾斜的底座安装机构包括用于防止调节螺钉移动的支撑件，所述支撑件具有安装在其上表面上的弹性构件和形成有夹子形状的V型止动件的板簧 具有分别形成在其上表面和垂直表面上的孔。 此外，板簧包括形成在其下表面上的引导部分，引导部分与倾斜柱基部的突起接触以支撑调节螺钉，并且形成在引导部分的端部处的倾斜部分 所述倾斜部分可移动地插入到形成在所述V型止动器的垂直表面上的孔中。

    Liquid crystal display apparatus and method of manufacturing the same
    7.
    发明授权
    Liquid crystal display apparatus and method of manufacturing the same 有权
    液晶显示装置及其制造方法

    公开(公告)号：US09151981B2

    公开(公告)日：2015-10-06

    申请号：US13188779

    申请日：2011-07-22

    申请人： Sung Hwan Hong ,  Soon Joon Rho ,  Jae-Soo Jang ,  Jun Ha Park

    发明人： Sung Hwan Hong ,  Soon Joon Rho ,  Jae-Soo Jang ,  Jun Ha Park

    IPC分类号： G02F1/1335

    CPC分类号： G02F1/1335 ,  G02F1/133524 ,  G02F1/133526 ,  G02F1/133528

    摘要： The viewing angle of a Liquid Crystal Display (LCD) apparatus is expanded by means of a sampled light redirecting layer, In one embodiment, the sampled light redirecting layer is formed as a compensation layer disposed between a top polarizing plate and the rest of a liquid crystal display panel having a first substrate, a second substrate, and a liquid crystal layer interposed therebetween. The compensation layer includes at least two optical path changing patterns disposed in interleaved manner. The two optical path changing patterns have different refractive indexes. As a result of the different refractive indices and shapes of the at least two different optical path changing patterns some of the light rays sampled out of the output of the rest of a liquid crystal display panel are directed in a first direction by means of reflection or refraction and some are directed in a different second direction, thereby improving a side visibility of the display apparatus.

    摘要翻译： 液晶显示器（LCD）装置的视角通过采样的光重定向层扩展。在一个实施例中，取样的光重定向层形成为设置在顶部偏振片和液体的其余部分之间的补偿层 晶体显示面板具有第一基板，第二基板和插入其间的液晶层。 补偿层包括以交错方式设置的至少两个光路改变图案。 两个光路改变图案具有不同的折射率。 由于至少两个不同光路改变图案的不同折射率和形状的结果，从液晶显示面板的其余部分的输出中采样的一些光线通过反射或第二方向被引向第一方向 折射，一些指向不同的第二方向，从而提高显示装置的侧面可视性。