Targeted 2′-O-methylation of telomerase non-coding RNA
    1.
    发明授权
    Targeted 2′-O-methylation of telomerase non-coding RNA 有权
    端粒酶非编码RNA靶向2'-O-甲基化

    公开(公告)号:US09273294B2

    公开(公告)日:2016-03-01

    申请号:US13809975

    申请日:2011-07-15

    申请人: Yi-Tao Yu Chao Huang

    发明人: Yi-Tao Yu Chao Huang

    摘要: Processes and C/D box small nucleolar RNAs (snoRNAs) for altering telomerase activity and altering telomerase length are described. The processes of the invention involve the use of C/D box snoRNAs for targeted 2′-O-methylation modification of nucleotides in a pseudoknot region of the telomerase RNA. Depending on their position, the 2′-O-methylation modifications can cause an increase in telomerase activity and subsequent telomere lengthening or a decrease in telomerase activity and subsequent telomere shortening.

    摘要翻译: 描述了用于改变端粒酶活性和改变端粒酶长度的方法和C / D盒小核仁RNA(snoRNA)。 本发明的方法涉及使用C / D盒snoRNA来进行端粒酶RNA假核素区域中核苷酸的靶向2'-O-甲基化修饰。 根据其位置,2'-O-甲基化修饰可导致端粒酶活性增加,随后端粒延长或端粒酶活性降低以及随后的端粒缩短。

    Headset
    2.
    外观设计
    Headset 有权

    公开(公告)号:USD661283S1

    公开(公告)日:2012-06-05

    申请号:US29369740

    申请日:2010-09-13

    申请人: Chao Huang

    设计人: Chao Huang

    STATUS-AWARE PERSONAL INFORMATION MANAGEMENT
    4.
    发明申请
    STATUS-AWARE PERSONAL INFORMATION MANAGEMENT 审中-公开
    状态 - 个人信息管理

    公开(公告)号:US20090177601A1

    公开(公告)日:2009-07-09

    申请号:US11970522

    申请日:2008-01-08

    IPC分类号: G06F15/18

    CPC分类号: H04L67/22 G06Q10/10

    摘要: Described is a technology by which personal information that comes into a computer system is intelligently managed according to current state data including user presence and/or user attention data. Incoming information is processed against the state data to determine whether corresponding data is to be output, and if so, what output modality or modalities to use. For example, if a user is present and busy, a notification may be blocked or deferred to avoid disturbing the user. Cost analysis may be used to determine the cost of outputting the data. In addition to user state data, the importance of the information, other state data, the cost of converting data to another format for output (e.g., text-to-speech), and/or user preference data, may factor into the decision. The output data may be modified (e.g., audio made louder) based on a current output environment as determined via the state data.

    摘要翻译: 描述了根据包括用户存在和/或用户关注数据的当前状态数据来智能地管理进入计算机系统的个人信息的技术。 根据状态数据处理传入信息,以确定是否输出相应的数据,如果是,则使用什么输出模态或模态。 例如,如果用户存在和忙碌,则可以阻止或延迟通知以避免干扰用户。 成本分析可用于确定输出数据的成本。 除了用户状态数据之外,信息的重要性,其他状态数据,将数据转换成用于输出的另一种格式(例如,文本到语音)和/或用户偏好数据的成本可以考虑到该决定中。 可以基于经由状态数据确定的当前输出环境来修改输出数据(例如,更大声音)。

    Data reuse method for blocking matching motion estimation
    5.
    发明申请
    Data reuse method for blocking matching motion estimation 有权
    用于阻塞匹配运动估计的数据重用方法

    公开(公告)号:US20070053439A1

    公开(公告)日:2007-03-08

    申请号:US11219720

    申请日:2005-09-07

    IPC分类号: H04N11/04

    CPC分类号: H04N19/433

    摘要: A data reuse method with level C+ for block matching motion estimation is disclosed. Compared to conventional Level C scheme, this invention can save large external memory bandwidth of motion estimation. The main idea is to reuse the overlapped searching region in the horizontal direction and partially reuse the overlapped searching region in the vertical direction. Several vertical successive current macroblocks are stitched, and the searching region of these current macroblocks is loaded, simultaneously. With the small overhead of internal memory, the reduction of external memory bandwidth is large. By case studies of H.264/AVC, the level C+ scheme can provide a good trade-off between the conventional Level C and D scheme.

    摘要翻译: 公开了一种用于块匹配运动估计的具有级别C +的数据重用方法。 与常规C级方案相比,本发明可以节省运动估计的大外部存储带宽。 主要思想是在水平方向重用重叠搜索区域,并在垂直方向部分重用重叠搜索区域。 缝合几个垂直连续的电流宏块,同时加载这些当前宏块的搜索区域。 由于内部存储器的开销较小,外部存储器带宽的减少很大。 通过对H.264 / AVC的案例研究,C +电平方案可以在常规C级和D级方案之间提供良好的权衡。

    Charger
    7.
    外观设计
    Charger 有权

    公开(公告)号:USD664920S1

    公开(公告)日:2012-08-07

    申请号:US29410978

    申请日:2012-01-13

    申请人: Chao Huang

    设计人: Chao Huang

    Headset
    8.
    外观设计
    Headset 有权

    公开(公告)号:USD643420S1

    公开(公告)日:2011-08-16

    申请号:US29375446

    申请日:2010-09-22

    申请人: Chao Huang

    设计人: Chao Huang

    PHONETIC SUGGESTION ENGINE
    9.
    发明申请
    PHONETIC SUGGESTION ENGINE 审中-公开
    电话建议发动机

    公开(公告)号:US20110184723A1

    公开(公告)日:2011-07-28

    申请号:US12693316

    申请日:2010-01-25

    IPC分类号: G06F17/20 G09B5/00

    摘要: A phonetic suggestion engine for providing word or phrase suggestions for an input letter string initially converts an input letter string into one or more query phoneme sequences. The conversion is performed via at least one standardized letter-to-sound (LTS) database. The phonetic suggestion engine further obtains a plurality of candidate phoneme sequences that are phonetically similar to the at query phoneme sequences from a pool of potential phoneme sequences. The phonetic suggestion engine then prunes the plurality of candidate phoneme sequences to generate scored phoneme sequences. The phonetic suggestion engine subsequently generates a plurality of ranked word or phrase suggestions based on the scored phoneme sequences.

    摘要翻译: 用于为输入字母串提供单词或短语建议的语音提示引擎最初将输入字母串转换成一个或多个查询音素序列。 转换通过至少一个标准化的字母对数(LTS)数据库执行。 语音建议引擎还从潜在的音素序列池中获得多个候选音素序列,这些候选音素序列与语音类似于查询音素序列。 语音建议引擎然后修剪多个候选音素序列以产生得分的音素序列。 语音建议引擎随后基于得分的音素序列产生多个排名的词或短语建议。

    Headset
    10.
    外观设计
    Headset 有权

    公开(公告)号:USD641739S1

    公开(公告)日:2011-07-19

    申请号:US29375445

    申请日:2010-09-22

    申请人: Chao Huang

    设计人: Chao Huang