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1.发明申请Mammalian Sweet and Amino Acid Heterodimeric Taste Receptors Comprising T1R3 and T1R1 有权包含T1R3和T1R1的哺乳动物甜氨基酸异二聚味道感受器公开(公告)号：US20110151483A1
公开(公告)日：2011-06-23
申请号：US12944515
申请日：2010-11-11
申请人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J. P. Ryba , Mark A. Hoon
发明人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J. P. Ryba , Mark A. Hoon
CPC分类号： G01N33/5076 , C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
摘要翻译： 本发明提供了包含T1R3和T1R1的甜或氨基酸味受体的分离的核酸和氨基酸序列，来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，对这种受体的抗体， 检测这种核酸和受体，以及筛选甜味和氨基酸味觉受体调节剂的方法。
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2.发明授权Mammalian sweet and amino acid heterodimeric taste receptors comprising T1R3 and T1R1 有权包含T1R3和T1R1的哺乳动物甜味和氨基酸异二聚体味觉受体公开(公告)号：US08470970B2
公开(公告)日：2013-06-25
申请号：US12944515
申请日：2010-11-11
申请人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J. P. Ryba , Mark A. Hoon
发明人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J. P. Ryba , Mark A. Hoon
IPC分类号： C07K14/705 , C07K19/00 , C12N15/62
CPC分类号： G01N33/5076 , C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
摘要翻译： 本发明提供了包含T1R3和T1R1的甜或氨基酸味受体的分离的核酸和氨基酸序列，来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，对这种受体的抗体， 检测这种核酸和受体，以及筛选甜味和氨基酸味觉受体调节剂的方法。
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公开(公告)号：US07588900B2
公开(公告)日：2009-09-15
申请号：US10190417
申请日：2002-07-03
申请人： Charles S Zuker , Nicholas J. P. Ryba , Jayaram Chandrashekar , Mark A Hoon , Yifeng Zhang , Greg Nelson
发明人： Charles S Zuker , Nicholas J. P. Ryba , Jayaram Chandrashekar , Mark A Hoon , Yifeng Zhang , Greg Nelson
IPC分类号： C07K14/705 , G01N33/566
CPC分类号： G01N33/5076 , C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
摘要翻译： 本发明提供了包含来自感觉G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽的分离的核酸和氨基酸味道受体的氨基酸序列，这些受体的抗体，检测此类核酸的方法 和受体以及筛选甜味和氨基酸味觉受体调节剂的方法。
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公开(公告)号：US07977060B2
公开(公告)日：2011-07-12
申请号：US12147415
申请日：2008-06-26
申请人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
发明人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
IPC分类号： C07K14/705 , C12N15/12 , G01N33/566
CPC分类号： C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
摘要翻译： 本发明提供了包含来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，这种受体的抗体，检测这种核酸和受体的方法的甜味受体的分离的核酸和氨基酸序列， 以及筛选甜味受体调节剂的方法。
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5.发明授权Mammalian sweet and amino acid heterodimeric taste receptors comprising T1R3 and T1R1 有权包含T1R3和T1R1的哺乳动物甜味和氨基酸异二聚体味觉受体公开(公告)号：US07842786B2
公开(公告)日：2010-11-30
申请号：US12121576
申请日：2008-05-15
申请人： Charles S Zuker , Nicholas J. P. Ryba , Jayaram Chandrashekar , Mark A Hoon , Yifeng Zhang , Gregory A Nelson
发明人： Charles S Zuker , Nicholas J. P. Ryba , Jayaram Chandrashekar , Mark A Hoon , Yifeng Zhang , Gregory A Nelson
IPC分类号： C07K14/705 , G01N33/567 , C12N15/12
CPC分类号： G01N33/5076 , C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising T1R3 and T1R1, two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
摘要翻译： 本发明提供了包含T1R3和T1R1的甜或氨基酸味受体的分离的核酸和氨基酸序列，来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，对这种受体的抗体， 检测这种核酸和受体，以及筛选甜味和氨基酸味觉受体调节剂的方法。
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公开(公告)号：US07507793B2
公开(公告)日：2009-03-24
申请号：US10645441
申请日：2003-08-20
申请人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
发明人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
IPC分类号： C07H21/04 , G01N33/53 , G01N33/567 , C12P21/06 , C07K14/00
CPC分类号： C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
摘要翻译： 本发明提供了包含来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，这种受体的抗体，检测这种核酸和受体的方法的甜味受体的分离的核酸和氨基酸序列， 以及筛选甜味受体调节剂的方法。
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公开(公告)号：US08198048B2
公开(公告)日：2012-06-12
申请号：US12721463
申请日：2010-03-10
申请人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
发明人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
IPC分类号： C12N15/12 , C07K14/705
CPC分类号： C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
摘要翻译： 本发明提供了包含来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，这种受体的抗体，检测这种核酸和受体的方法的甜味受体的分离的核酸和氨基酸序列， 以及筛选甜味受体调节剂的方法。
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公开(公告)号：US07402400B2
公开(公告)日：2008-07-22
申请号：US09927315
申请日：2001-08-10
申请人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
发明人： Charles S. Zuker , Nicholas J. P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
IPC分类号： G01N33/566 , C07K14/705
CPC分类号： C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
摘要翻译： 本发明提供了包含来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，这种受体的抗体，检测这种核酸和受体的方法的甜味受体的分离的核酸和氨基酸序列， 以及筛选甜味受体调节剂的方法。
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公开(公告)号：US20080318251A1
公开(公告)日：2008-12-25
申请号：US12121576
申请日：2008-05-15
申请人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J.P. Ryba , Mark A. Hoon
发明人： Charles S. Zuker , Jayaram Chandrashekar , Greg Nelson , Yifeng Zhang , Nicholas J.P. Ryba , Mark A. Hoon
IPC分类号： G01N33/566 , C07K14/47 , C12N5/06 , C12N5/08
CPC分类号： G01N33/5076 , C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet or amino acid taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.
摘要翻译： 本发明提供了包含来自感觉G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽的分离的核酸和氨基酸味道受体的氨基酸序列，这些受体的抗体，检测此类核酸的方法 和受体以及筛选甜味和氨基酸味觉受体调节剂的方法。
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公开(公告)号：US20110244514A1
公开(公告)日：2011-10-06
申请号：US12721463
申请日：2010-03-10
申请人： Charles S. Zuker , Nicholas J.P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
发明人： Charles S. Zuker , Nicholas J.P. Ryba , Gregory A. Nelson , Mark A. Hoon , Jayaram Chandrashekar , Yifeng Zhang
CPC分类号： C07K14/705
摘要： The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
摘要翻译： 本发明提供了包含来自感官G蛋白偶联受体的T1R家族的两种异源G蛋白偶联受体多肽，这种受体的抗体，检测这种核酸和受体的方法的甜味受体的分离的核酸和氨基酸序列， 以及筛选甜味受体调节剂的方法。
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