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公开(公告)号:US20130296377A1
公开(公告)日:2013-11-07
申请号:US13826725
申请日:2013-03-14
申请人: Christopher Michael ADAMS , Charles BABU , Michael Paul CAPPARELLI , Jian DING , Takeru EHARA , Keith JENDZA , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Xue LIANG , Nello MAINOLFI , James J. POWERS , Michael H. SERRANO-WU , Chun ZHANG
发明人: Christopher Michael ADAMS , Charles BABU , Michael Paul CAPPARELLI , Jian DING , Takeru EHARA , Keith JENDZA , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Xue LIANG , Nello MAINOLFI , James J. POWERS , Michael H. SERRANO-WU , Chun ZHANG
IPC分类号: C07D491/048 , A61K31/4184 , C07D413/06 , A61K45/06 , C07D403/14 , C07D401/14 , A61K31/4439 , C07D403/06 , A61K31/423
CPC分类号: A61K31/4184 , A61K31/423 , A61K31/4245 , A61K31/4439 , A61K45/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/14 , C07D413/06 , C07D413/14 , C07D487/04 , C07D491/048
摘要: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.