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    ORGAN PERFUSION APPARATUS WITH DOWNSTREAM FLOW CONTROL
    4.
    发明申请
    ORGAN PERFUSION APPARATUS WITH DOWNSTREAM FLOW CONTROL 审中-公开
    具有下游流量控制的有机吸收装置

    公开(公告)号：US20140017662A1

    公开(公告)日：2014-01-16

    申请号：US13545281

    申请日：2012-07-10

    申请人： David KRAVITZ ,  Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Matthew COPITHORNE ,  Brian L. OTTS ,  Peter DEMUYLDER

    发明人： David KRAVITZ ,  Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Matthew COPITHORNE ,  Brian L. OTTS ,  Peter DEMUYLDER

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0247

    摘要： An organ perfusion apparatus may include at least two tubes connected to an organ or tissue. A method of perfusing an organ or tissue may include connecting a first end of each of the at least two tubes to an organ or tissue, applying a fluid motive force to a perfusion fluid in the two tubes to force the fluid through the two tubes into the organ or tissue, and perfusing the organ or tissue through the at least two tubes such that the fluid motive force, provided by, e.g., a pump, and backpressure generated by the organ or tissue, establishes a flow balance between the at least two tubes. The flow balance may be altered without altering the fluid motive force that is applied.

    摘要翻译： 器官灌注装置可以包括连接到器官或组织的至少两个管。 灌注器官或组织的方法可以包括将至少两个管中的每一个的第一端连接到器官或组织，将流体动力施加到两个管中的灌注流体，以迫使流体通过两个管进入 所述器官或组织，并且通过所述至少两个管灌注所述器官或组织，使得由例如泵提供的流体动力和由所述器官或组织产生的背压在所述至少两个管之间建立流动平衡 管。 可以改变流动平衡而不改变施加的流体动力。

    CANNULA WITH FLOATING CLAMP MEMBER
    5.
    发明申请
    CANNULA WITH FLOATING CLAMP MEMBER 有权
    带浮动夹子的肛门

    公开(公告)号：US20140017660A1

    公开(公告)日：2014-01-16

    申请号：US13545185

    申请日：2012-07-10

    申请人： Christopher P. STEINMAN ,  Jason A. BELTON ,  Kirk C. PALMERTON ,  Karl H. BEITZEL ,  Rick W. WALKER ,  Matthew COPITHORNE ,  Brian OTTS ,  James V. GUARRERA

    发明人： Christopher P. STEINMAN ,  Jason A. BELTON ,  Kirk C. PALMERTON ,  Karl H. BEITZEL ,  Rick W. WALKER ,  Matthew COPITHORNE ,  Brian OTTS ,  James V. GUARRERA

    IPC分类号： A01N1/02 ,  F16L3/00

    CPC分类号： A01N1/0247 ,  A61B17/122 ,  A61B17/28 ,  A61B2017/00907 ,  A61B2017/00969 ,  A61B2017/2808

    摘要： A cannula has a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end, the cannula being in a closed position when the first and second clamping ends are brought together. A first clamp member is located at the first clamping end and has a first passage. A second clamp member is rotatably attached to the arm member at the second clamping end and has a second passage. The first and second passages form a combined passage when the clamp is in the closed position. The cannula may have a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to lock the cannula in the closed position.

    摘要翻译： 套管具有纵向底座构件，该纵向底座构件具有第一夹紧端和纵向臂构件，所述纵向臂构件可枢转地附接到纵向底座构件并且具有第二夹紧端，当第一和第二夹紧端部接合在一起时，套管处于关闭位置。 第一夹紧构件位于第一夹紧端并且具有第一通道。 第二夹紧构件在第二夹持端处可旋转地附接到臂构件并具有第二通道。 当夹具处于关闭位置时，第一和第二通道形成组合的通道。 套管可以具有定位在臂构件上的第一锁定构件和定位在基座构件上的第二锁定构件。 第一和第二锁定构件相互作用以将套管锁定在关闭位置。

    PERFUSION APPARATUS WITH REDUCED PRESSURE FLUCTUATIONS, AND BUBBLE TRAP
    6.
    发明申请
    PERFUSION APPARATUS WITH REDUCED PRESSURE FLUCTUATIONS, AND BUBBLE TRAP 有权
    具有降低压力波动的膨胀装置和气泡

    公开(公告)号：US20140017658A1

    公开(公告)日：2014-01-16

    申请号：US13545060

    申请日：2012-07-10

    申请人： Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Rick W. WALKER ,  Evan D. SHAPIRO ,  Aaron R. FERBER ,  Rodney H. MONSON ,  John STARK ,  Ross LOCKWOOD

    发明人： Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Rick W. WALKER ,  Evan D. SHAPIRO ,  Aaron R. FERBER ,  Rodney H. MONSON ,  John STARK ,  Ross LOCKWOOD

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0247 ,  A61M1/3627 ,  A61M1/3638 ,  A61M5/36

    摘要： An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.

    摘要翻译： 用于分离可能夹带在灌注液中的气泡的装置防止这种气泡继续下游并进入器官或组织。 该装置可以包括具有顶壁，底壁和侧壁的室。 腔室可以包括被配置为允许气体和液体中的至少一个进入腔室的入口，被配置为允许至少气体离开腔室的空气开口和被配置为允许至少液体离开腔室的第一液体开口。 该装置可以用作减少或消除液体流动和压力的脉动的蓄能器。 该装置可以包括最初体积的气体，最初或通过气体的积聚，使得液体中的流动和压力波动被抑制或消除。 该装置可以包括在该室的壁中的取样口。

    ORGAN TRANSPORTER WITH OXYGEN GENERATION
    7.
    发明申请
    ORGAN TRANSPORTER WITH OXYGEN GENERATION 审中-公开
    具有氧气生成的有机运输机

    公开(公告)号：US20140017665A1

    公开(公告)日：2014-01-16

    申请号：US13545514

    申请日：2012-07-10

    申请人： Christopher P. STEINMAN ,  David KRAVITZ ,  Aaron R. FERBER ,  Ross LOCKWOOD ,  Rodney H. MONSON ,  Evan D. SHAPIRO

    发明人： Christopher P. STEINMAN ,  David KRAVITZ ,  Aaron R. FERBER ,  Ross LOCKWOOD ,  Rodney H. MONSON ,  Evan D. SHAPIRO

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0247

    摘要： An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.

    摘要翻译： 用于灌注器官或组织的装置包括用于灌注器官或组织的灌注回路; 用于氧化灌注液的氧合器，其通过灌注回路循环; 以及氧气供应装置，例如氧气浓缩器或氧气发生器，其被配置为向氧合器供应氧气。 灌注器官或组织的方法包括从诸如氧气浓缩器和氧气发生器的装置产生氧气; 将产生的氧优选作为产生氧气供应给灌注液以使灌注液充氧; 并用含氧灌注液灌注器官或组织。 所产生的氧优选具有大于空气中的氧浓度的浓度。

    ORGAN TRANSPORTER WITH TILT AND/OR SHOCK SENSING
    8.
    发明申请
    ORGAN TRANSPORTER WITH TILT AND/OR SHOCK SENSING 有权
    有倾斜和/或震动传感器的组织运输机

    公开(公告)号：US20140017663A1

    公开(公告)日：2014-01-16

    申请号：US13545442

    申请日：2012-07-10

    申请人： Christopher P. STEINMAN ,  John STARK ,  Joel C. HAGAN ,  Aaron R. FERBER ,  Rodney H. MONSON ,  Evan D. SHAPIRO

    发明人： Christopher P. STEINMAN ,  John STARK ,  Joel C. HAGAN ,  Aaron R. FERBER ,  Rodney H. MONSON ,  Evan D. SHAPIRO

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0247 ,  A01N1/0273

    摘要： An apparatus for perfusing an organ or tissue includes a perfusion circuit configured to perfuse the organ or tissue; at least one shock and/or tilt detector such as an accelerometer; and a controller. The controller may be configured to control perfusion based upon a signal received from the accelerometer, which may include stopping and/or starting the perfusion based upon the signal. The controller may also or alternatively sense and/or record shocks experienced by the apparatus.

    摘要翻译： 用于灌注器官或组织的装置包括构造成灌注器官或组织的灌注回路; 至少一个冲击和/或倾斜检测器，例如加速度计; 和控制器。 控制器可以被配置为基于从加速度计接收的信号来控制灌注，其可以包括基于该信号停止和/或启动灌注。 控制器还可以或者可选地感测和/或记录设备经历的冲击。