-
公开(公告)号：US08618293B2
公开(公告)日：2013-12-31
申请号：US12663821
申请日：2008-06-17
CPC分类号： C12Q1/004 , C07F15/0026 , C07F15/0053
摘要： The present invention relates to ruthenium and osmium complexes of Formula [M(A)w(B)x(C)y]m(Xz)n, per se and the use of ruthenium and osmium complexes of Formula I as redox mediators in electrochemical biosensors.
摘要翻译： 本发明涉及式[M（A）w（B）x（C）y] m（Xz）n本身的钌和锇络合物以及式I的钌和锇络合物作为氧化还原介体在电化学 生物传感器
-
公开(公告)号：US20110262950A1
公开(公告)日：2011-10-27
申请号：US12663821
申请日：2008-06-17
CPC分类号： C12Q1/004 , C07F15/0026 , C07F15/0053
摘要： The present invention relates to ruthenium and osmium complexes of Formula [M(A)w(B)xCy]m(Xz)n, per se and the use of ruthenium and osmium complexes of Formula I as redox mediators in electrochemical biosensors.
摘要翻译： 本发明涉及式[M（A）w（B）xCy] m（Xz）n本身的钌和锇络合物以及在电化学生物传感器中使用式I的钌和锇络合物作为氧化还原介体。
-
公开(公告)号：US06511592B1
公开(公告)日：2003-01-28
申请号：US09600749
申请日：2000-10-02
IPC分类号： G01N27327
CPC分类号： C12Q1/005
摘要： A sensor for pentachlorophenol comprises a sensor electrode carrying a pentachlorophenol hydroxylase, and a counter electrode. An assay method comprises maintaining a potential difference between the electrodes and observing a current associated with enzyme-catalyzed oxidation of the pentachlorophenol.
摘要翻译： 五氯苯酚的传感器包括携带五氯苯酚羟化酶的传感器电极和对电极。 测定方法包括维持电极之间的电位差并观察与五氯苯酚的酶催化氧化相关的电流。
-
公开(公告)号：US20080044882A1
公开(公告)日：2008-02-21
申请号：US10590426
申请日：2005-02-23
CPC分类号： C12P7/00
摘要： The present invention provides a method of carrying out an oxidation reaction catalysed by a monooxygenase enzyme and using hydrogen peroxide as an oxidant, in which reaction a low level of oxidation damage of the monooxygenase occurs, said method comprising producing the hydrogen peroxide simultaneously with the oxidation reaction, wherein the hydrogen peroxide is produced at a rate less than or equal to the rate at which it is used in the reaction or said method comprising carrying out the reaction in the presence of an H2O2 or hydroxyl radical sequestering agent that controls the H2O2 or hydroxyl radical concentration.
摘要翻译： 本发明提供一种进行由单加氧酶催化的氧化反应并使用过氧化氢作为氧化剂的方法，其中发生单加氧酶的低水平的氧化损伤，所述方法包括与氧化物同时生产过氧化氢 反应，其中所述过氧化氢的产生速率小于或等于其在反应中使用的速率或所述方法，包括在H 2 O 2存在下进行反应， 或者羟基自由基螯合剂，其控制H 2 O 2 O 2或羟基自由基浓度。
-
公开(公告)号：US5727548A
公开(公告)日：1998-03-17
申请号：US469205
申请日：1995-06-06
IPC分类号： A61B5/00 , C12Q1/00 , C12Q1/68 , G01N27/403 , G01N33/487 , G01N33/543
CPC分类号： G01N33/5438 , A61B5/1486 , A61B5/6848 , C12Q1/001 , C12Q1/004 , C12Q1/6825 , G01N27/4035 , A61B2560/0418 , Y10T29/4914 , Y10T29/49153 , Y10T29/49169 , Y10T29/49224
摘要： A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; a first conductor and a second conductor each extend along the support and comprise means for connection to the circuitry. An active electrode, positioned to contact the liquid mixture and the first conductor, comprises a single layer deposit of an enzyme capable of catalyzing a reaction involving the compound, a conductive material, and an electron mediator, capable of transferring electrons between the enzyme-catalyzed reaction and the first conductor. A reference electrode is positioned to contact the mixture and the second conductor. The system includes circuitry adapted to provide an electrical signal representative of the current. The two-electrode strip is manufactured, e.g., by screen printing, an admixture of an enzyme a conductive material, and a mediator as a single layer onto the substrate.
摘要翻译： 检测液体混合物中的化合物的当前代表的传感器系统具有适于可释放地附接到信号读出电路的双电极条。 条带包括适于可释放地附接到读出电路的细长支撑件（优选是平坦的）; 第一导体和第二导体各自沿着支撑件延伸并且包括用于连接到电路的装置。 定位成接触液体混合物和第一导体的活性电极包括能够催化涉及化合物，导电材料和电子介体的反应的酶的单层沉积物，其能够在酶催化的 反应和第一个导体。 定位参考电极以接触混合物和第二导体。 该系统包括适于提供代表电流的电信号的电路。 双电极条例如通过丝网印刷，酶导电材料的混合物和作为单层的介体制成在基底上。
-
公开(公告)号：US06231746B1
公开(公告)日：2001-05-15
申请号：US09180279
申请日：1999-03-18
IPC分类号： C25B300
摘要： A method of electrochemistry is conducted by conducting the direct electrochemistry of a monooxygenase enzyme in the absence of mediators. A method of electrochemistry is conducted by conducting the direct electrochemistry of an hydroxylase enzyme in the absence of mediators.
摘要翻译： 通过在不存在介质的情况下进行单加氧酶的直接电化学来进行电化学方法。 通过在不存在介质的情况下进行羟化酶的直接电化学来进行电化学方法。
-
公开(公告)号：US5682884A
公开(公告)日：1997-11-04
申请号：US281131
申请日：1994-07-27
IPC分类号： A61B5/00 , C12Q1/00 , C12Q1/68 , G01N27/403 , G01N33/487 , G01N33/543 , A61B5/05
CPC分类号： A61B5/1486 , A61B5/14865 , A61B5/6848 , C12Q1/001 , C12Q1/004 , G01N27/4035 , G01N33/5438 , A61B2560/0418
摘要： A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; a first conductor and a second conductor each extend along the support and comprise means for connection to the circuitry. An active electrode, positioned to contact the liquid mixture and the first conductor, comprises a deposit of an enzyme capable of catalyzing a reaction involving the compound and (preferably) an electron mediator, capable of transferring electrons between the enzyme-catalyzed reaction and the first conductor. A reference electrode is positioned to contact the mixture and the second conductor. The system includes circuitry adapted to provide an electrical signal representative of the current. The two-electrode strip is manufactured, e.g., by screen printing the enzyme (and preferably the mediator) onto the substrate.
摘要翻译： 检测液体混合物中的化合物的当前代表的传感器系统具有适于可释放地附接到信号读出电路的双电极条。 条带包括适于可释放地附接到读出电路的细长支撑件（优选是平坦的）; 第一导体和第二导体各自沿着支撑件延伸并且包括用于连接到电路的装置。 定位成接触液体混合物和第一导体的活性电极包括能够催化涉及化合物和（优选）电子介体的反应的酶的沉积物，其能够在酶催化的反应和第一个 导体。 定位参考电极以接触混合物和第二导体。 该系统包括适于提供代表电流的电信号的电路。 例如通过将酶（优选介体）丝网印刷到基底上来制造双电极条。
-
公开(公告)号：US06740214B1
公开(公告)日：2004-05-25
申请号：US09674991
申请日：2001-03-12
IPC分类号： G01N27327
CPC分类号： G01N27/403
摘要： There is disclosed a biosensor comprising a conducting surface, a layer of dielectric material overlying the conducting surface, a plurality of micro electrodes constituted by a plurality of pores extending through the thickness of said dielectric layer, a biopolymer positioned on the conducting surface in said pores, and a counter electrode arranged such that electrical connection can be made between it and at least part of said conducting surface by a fluid to be assessed. Such a device can be made using a method comprising the steps of providing a conducting surface; providing a layer of dielectric material adjacent to said conducting surface, said dielectric material comprising a plurality of pores extending through the thickness of the dielectric layer; providing a biopolymer on the conducting surface in said pores; and providing a counter electrode insulated from said conducting surface.
摘要翻译： 公开了一种生物传感器，其包括导电表面，覆盖在导电表面上的介电材料层，多个微电极，其由延伸穿过所述介电层厚度的多个孔构成，生物聚合物位于所述孔中的导电表面上 以及相对电极，其布置成使得可以通过待评估的流体在其与所述导电表面的至少一部分之间进行电连接。 可以使用包括以下步骤的方法制造这种器件：提供导电表面;提供与所述导电表面相邻的电介质材料层，所述介电材料包括延伸穿过介电层厚度的多个孔;提供生物聚合物 在所述孔中的导电表面上; 并提供与所述导电表面绝缘的对电极。
-
公开(公告)号：US5820551A
公开(公告)日：1998-10-13
申请号：US470352
申请日：1995-06-06
IPC分类号： A61B5/00 , C12Q1/00 , C12Q1/68 , G01N27/403 , G01N33/487 , G01N33/543 , A61B5/05
CPC分类号： A61B5/1486 , A61B5/14865 , A61B5/6848 , C12Q1/001 , C12Q1/004 , G01N27/4035 , G01N33/5438 , A61B2560/0418
摘要： A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; a first conductor and a second conductor each extend along the support and comprise means for connection to the circuitry. An active electrode, positioned to contact the liquid mixture and the first conductor, comprises a single layer deposit of an enzyme capable of catalyzing a reaction involving the compound, a conductive material and an electron mediator, capable of transferring electrons between the enzyme-catalyzed reaction and the first conductor. A reference electrode is positioned to contact the mixture and the second conductor. The system includes circuitry adapted to provide an electrical signal representative of the current. The two-electrode strip is manufactured, e.g., by screen printing an admixture of an enzyme, a conductive material, and a mediator as a single layer onto the substrate.
摘要翻译： 检测液体混合物中的化合物的当前代表的传感器系统具有适于可释放地附接到信号读出电路的双电极条。 条带包括适于可释放地附接到读出电路的细长支撑件（优选是平坦的）; 第一导体和第二导体各自沿着支撑件延伸并且包括用于连接到电路的装置。 定位成接触液体混合物和第一导体的活性电极包括能够催化涉及化合物，导电材料和电子介体的反应的酶的单层沉积物，其能够在酶催化反应之间传递电子 和第一个导体。 定位参考电极以接触混合物和第二导体。 该系统包括适于提供代表电流的电信号的电路。 双电极条例如通过将酶，导电材料和介体的混合物作为单层丝网印刷到基底上来制造。
-
公开(公告)号：US20110031988A1
公开(公告)日：2011-02-10
申请号：US12697712
申请日：2010-02-01
IPC分类号： G01R27/08
CPC分类号： C12Q1/001
摘要： The invention relates to reducing signal distortions occurring when a potential is applied to an electrochemical cell. Electrochemical measurements are obtained in the presence of a specific chemical entity which is an aminoglycoside, an organic polyamine and/or a substance capable of raising the ionic strength of the sample.
摘要翻译： 本发明涉及减少当将电位施加到电化学电池时发生的信号失真。 在特定化学实体存在下获得电化学测量，所述特定化学实体是氨基糖苷，有机多胺和/或能够提高样品的离子强度的物质。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.023 秒)
