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公开(公告)号:US20150150845A1
公开(公告)日:2015-06-04
申请号:US14619242
申请日:2015-02-11
发明人: Kazutomo KINOSHITA , Kohsuke ASOH , Noriyuki FURUICHI , Toshiya ITO , Hatsuo KAWADA , Nobuya ISHII , Hiroshi SAKAMOTO , WooSang HONG , MinJeong PARK , Yoshiyuki ONO , Yasuharu KATO , Kenji MORIKAMI , Takashi EMURA , Nobuhiro OIKAWA
IPC分类号: A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/7056 , A61K31/5377 , A61K31/541 , A61K31/496 , A61K31/454 , A61K31/506
CPC分类号: C07D209/58 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D209/56 , C07D209/88 , C07D307/77 , C07D307/78 , C07D307/92 , C07D333/50 , C07D333/52 , C07D333/76 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/14 , C07D471/04 , C07D471/10 , C07D491/107 , C07F7/0834 , C07H15/26
摘要: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
摘要翻译: 由下述通式(I)表示的化合物或其盐或溶剂化物,其可用作ALK抑制剂,并且可用于预防或治疗伴有ALK异常的疾病,例如癌症,癌症转移 ,抑郁症或认知功能障碍(包括在公式中的符号的含义如说明书中所给出)。
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公开(公告)号:US20230142119A1
公开(公告)日:2023-05-11
申请号:US17860589
申请日:2022-07-08
发明人: Kazutomo KINOSHITA , Kohsuke ASOH , Noriyuki FURUICHI , Toshiya ITO , Hatsuo KAWADA , Nobuya ISHII , Hiroshi SAKAMOTO , WooSang HONG , MinJeong PARK , Yoshiyuki ONO , Yasuharu KATO , Kenji MORIKAMI , Takashi EMURA , Nobuhiro OIKAWA
IPC分类号: C07D209/58 , C07D209/88 , C07D307/77 , C07D307/92 , C07D333/50 , C07D333/76 , C07D401/04 , C07D401/06 , C07D403/04 , C07D405/12 , C07D405/14 , C07D471/04 , C07D491/107 , C07D209/56 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D307/78 , C07D333/52 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/14 , C07D471/10 , C07F7/08 , C07H15/26
CPC分类号: C07D209/58 , C07D209/88 , C07D307/77 , C07D307/92 , C07D333/50 , C07D333/76 , C07D401/04 , C07D401/06 , C07D403/04 , C07D405/12 , C07D405/14 , C07D471/04 , C07D491/107 , C07D209/56 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D307/78 , C07D333/52 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/14 , C07D471/10 , C07F7/0834 , C07H15/26
摘要: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder:
(meanings of the symbols that are included in the formula are as given in the specification).-
公开(公告)号:US20220306578A1
公开(公告)日:2022-09-29
申请号:US16862125
申请日:2020-04-29
发明人: Kazutomo KINOSHITA , Kohsuke ASOH , Noriyuki FURUICHI , Toshiya ITO , Hatsuo KAWADA , Nobuya ISHII , Hiroshi SAKAMOTO , WooSang HONG , MinJeong PARK , Yoshiyuki ONO , Yasuharu KATO , Kenji MORIKAMI , Takashi EMURA , Nobuhiro OIKAWA
IPC分类号: C07D209/58 , C07D209/88 , C07D307/77 , C07D307/92 , C07D333/50 , C07D333/76 , C07D401/04 , C07D401/06 , C07D403/04 , C07D405/12 , C07D405/14 , C07D471/04 , C07D491/107 , C07D209/56 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D307/78 , C07D333/52 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/14 , C07D471/10 , C07F7/08 , C07H15/26
摘要: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
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公开(公告)号:US20200017442A1
公开(公告)日:2020-01-16
申请号:US16239839
申请日:2019-01-04
发明人: Kazutomo KINOSHITA , Kohsuke ASOH , Noriyuki FURUICHI , Toshiya ITO , Hatsuo KAWADA , Nabuya ISHII , Hiroshi SAKAMOTO , WooSang HONG , MinJeong PARK , Yoshiyuki ONO , Yasuharu KATO , Kenji MORIKAMI , Takashi EMURA , Nobuhiro OIKAWA
IPC分类号: C07D209/58 , C07H15/26 , C07F7/08 , C07D471/10 , C07D413/14 , C07D409/12 , C07D403/12 , C07D401/14 , C07D401/12 , C07D333/52 , C07D307/78 , A61K31/7056 , A61K31/541 , A61K31/5377 , A61K31/506 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/4178 , A61K31/404 , C07D209/56 , C07D491/107 , C07D471/04 , C07D405/14 , C07D405/12 , C07D403/04 , C07D401/06 , C07D401/04 , C07D333/76 , C07D333/50 , C07D307/92 , C07D307/77 , C07D209/88
摘要: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
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公开(公告)号:US20160340308A1
公开(公告)日:2016-11-24
申请号:US15221926
申请日:2016-07-28
发明人: Kazutomo Kinoshita , Kohsuke ASOH , Noriyuki FURUICHI , Toshiya ITO , Hatsuo KAWADA , Nobuya ISHll , Hiroshi SAKAMOTO , WooSang HONG , MinJeong PARK , Yoshiyuki ONO , Yasuharu KATO , Kenji MORIKAMI , Takashi EMURA , Nobuhiro OIKAWA
IPC分类号: C07D209/58 , C07D403/12 , C07D405/12 , C07F7/08 , C07D405/14 , C07D401/14 , C07D403/04 , C07D413/14 , C07D401/04 , C07D401/06 , C07D409/12 , C07D471/04 , C07D491/107 , C07H15/26 , C07D471/10 , C07D333/52 , C07D307/78 , C07D401/12
CPC分类号: C07D209/58 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D209/56 , C07D209/88 , C07D307/77 , C07D307/78 , C07D307/92 , C07D333/50 , C07D333/52 , C07D333/76 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/14 , C07D471/04 , C07D471/10 , C07D491/107 , C07F7/0834 , C07H15/26
摘要: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
摘要翻译: (公式中包含的符号的含义如规范中所述)。
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