公开(公告)号：US20210177893A1

公开(公告)日：2021-06-17

申请号：US17110249

申请日：2020-12-02

Applicant: Chun Nan Lin

Inventor： Chun Nan Lin

IPC: A61K33/24 ,  A61K9/06 ,  A61K47/38 ,  A61K47/10 ,  A61P19/08

Abstract: A composition and method of preventing and treating all forms of osteonecrosis of the jaw are disclosed. The composition is comprised of 0.005 %-1.5% weight/volume (w/v) stannous salt, such as stannous fluoride, stannous chloride, or similar and may take the form of gel or similar. The prevention and treatment includes the application of the composition in the oral cavity and other body areas affected by Medication-Related Osteonecrosis of the Jaw (MRONJ).

公开(公告)号：US20210169777A1

公开(公告)日：2021-06-10

申请号：US17106132

申请日：2020-11-29

Applicant: Chun Nan Lin

Inventor： Chun Nan Lin

IPC: A61K9/00 ,  A61K9/06 ,  A61K8/04 ,  A61Q11/00 ,  A61K8/21 ,  A61K33/06 ,  A61K8/19 ,  A61K8/24 ,  A61K33/42 ,  A61K33/20 ,  A61K8/20 ,  A61K31/047 ,  A61K8/34 ,  A61K8/73 ,  A61K47/38

Abstract: The present invention provides an orally ingestible composition comprising electrolytes, Methyl Hydroxybenzoate, and sorbitol for treating xerostomia (dry mouth) and associated disorders, with very good results in provide a protective coating inside the mouth and throat, in alleviating the symptoms of xerostomia, including difficulties in eating and speaking, the pain associated to xerostomia, improving the quality of life on affected people as well. Sweeteners, colorants, and preservatives also combined in the artificial saliva. Methyl Hydroxybenzoate acts as a lubricant and as a delivery vehicle for water from the composition to moisten the mouth. The artificial saliva composition is used to keep moisture in the mouth when there is little or no natural saliva is produced, providing relief from dry mouth, as a symptom of xerostomia, mucositis, and stomatitis, as well as general inflammation and/or ulceration of mucous membranes, while avoiding pH imbalances which may lead secondary to tooth decay and/or injury to the upper digestive tract including the oral cavity, oropharynx, or esophagus. The pH buffering system includes acidic and basic components. The electrolytes include potassium, sodium, magnesium, calcium, chloride and phosphate together with fluoride. The composition of the invention has also been proved in clinically to prevent demineralization from acid conditions and decreasing risk of oral thrush. The composition of the invention can apply by persons with certain diseases, such as some cancers, radiation, chemotherapy, old age, smoking, and both prescribed and over the counter medications with side effect.

公开(公告)号：US08781190B2

公开(公告)日：2014-07-15

申请号：US13584262

申请日：2012-08-13

Applicant: Chun Nan Lin ,  Chung Ping Chuang ,  Che Liang Tsai

Inventor： Chun Nan Lin ,  Chung Ping Chuang ,  Che Liang Tsai

IPC: G06K9/00

CPC classification number: G06T5/008 ,  G06K9/3233 ,  G06T2207/30041

Abstract: An image-recognition assisting method includes the steps of using an examination instrument to generate an image having a split-image area formed thereon; setting a region-of-interest (ROI) around the split-image area of the generated image; performing a pixel luminance addition processing on the ROI, so that all pixels in the ROI have increased luminance contrast; and performing a contrast correction on the ROI having increased luminance contrast, so that the luminance contrast between the split-image area and the area surrounding the split-image area in the ROI is further increased. The image-recognition assisting method optimizes the image generated by the conventional ophthalmic examination instrument, such as a fundus camera, to increase the sharpness and the luminance contrast of the image output by the fundus camera, so that an examiner can easily recognize two offset rectangular image parts in the split-image area and align them with each other to focus the examination instrument.

Abstract translation: 图像识别辅助方法包括以下步骤：使用检查仪器生成其上形成有分割图像区域的图像; 在生成的图像的分割图像区域周围设置感兴趣区域（ROI）; 对ROI进行像素亮度附加处理，使得ROI中的所有像素具有增加的亮度对比度; 并且对具有增加的亮度对比度的ROI执行对比度校正，使得分割图像区域和ROI中的分割图像区域周围的区域之间的亮度对比度进一步增加。 图像识别辅助方法优化诸如眼底照相机的常规眼科检查仪产生的图像，以增加由眼底照相机输出的图像的清晰度和亮度对比度，使得检查者可以容易地识别两个偏移矩形 在分割图像区域中的图像部分并将它们彼此对准以对准检查仪器。