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公开(公告)号:US20070003116A1
公开(公告)日:2007-01-04
申请号:US11172415
申请日:2005-06-29
申请人: Chun Yuan , Thomas Hatsukami , Renu Virmani , Jianming Cai , William Kerwin , Marina Ferguson
发明人: Chun Yuan , Thomas Hatsukami , Renu Virmani , Jianming Cai , William Kerwin , Marina Ferguson
IPC分类号: G06K9/00
CPC分类号: G06T7/0012 , A61B5/02007 , A61B5/055 , A61B5/7275 , A61B6/504 , A61B8/0833 , G06F19/00 , G06T2207/30101
摘要: A method for characterizing the risk associated with atherosclerosis is disclosed. The method uses one or more images of cross-sections of the artery or other vessel of interest to identify and locate components of the atherosclerotic deposit, including any hemorrhage, necrotic core, and calcification, and to determine the status and composition of the fibrous cap. In one embodiment, high resolution MRI images are utilized, although other imaging modalities may alternatively be used. A simple scoring system is applied that accounts for the presence of these components and more heavily weights the presence of these components in the juxtaluminal portion of the deposit. The status of the fibrous cap (intact or ruptured) and the composition of the fibrous cap (collagen or mixed tissue) are also incorporated into a final atherosclerosis risk score.
摘要翻译: 公开了描述与动脉粥样硬化相关的风险的方法。 该方法使用动脉或其他所需血管的横截面的一个或多个图像来识别和定位动脉粥样硬化沉积物的组分,包括任何出血,坏死核心和钙化,并确定纤维帽的状态和组成 。 在一个实施例中,利用了高分辨率MRI图像,但是也可以使用其它成像模式。 应用一个简单的评分系统来解释这些组件的存在,并且更重地将这些组件的存在权重存放在存款的两个部分中。 纤维帽(完整或破裂)的状态和纤维帽(胶原蛋白或混合组织)的组成也被纳入最终的动脉粥样硬化风险评分。