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    Pharmaceutical composition for inhibiting topoisomerase I and method for exploiting drug
    1.
    发明申请
    Pharmaceutical composition for inhibiting topoisomerase I and method for exploiting drug 审中-公开
    用于抑制拓扑异构酶I的药物组合物和开发药物的方法

    公开(公告)号：US20100144763A1

    公开(公告)日：2010-06-10

    申请号：US12592965

    申请日：2009-12-04

    申请人： Chun-Mao Lin ,  Chwen-Ming Shih ,  Jui-Yu Wu

    发明人： Chun-Mao Lin ,  Chwen-Ming Shih ,  Jui-Yu Wu

    IPC分类号： A61K31/519 ,  A61P35/00

    CPC分类号： A61K31/519

    摘要： The invention relates to the compounds isolated from Evodia rutaecarpa (Juss.), in that has been demonstrated to inhibit topoisomerase I. Evodiamine, an alkaloidal compound is reported the topoisomerase I inhibitory activity. The effect of evodiamine acts by stabilizing the covalent complex between topoisomerase I and DNA, which results in a blockade of DNA replication and transcription.

    摘要翻译： 本发明涉及从杜鹃花（Juss。）中分离的化合物，已被证明能够抑制拓扑异构酶I.伊伏迪胺是一种生物碱化合物，报道了拓扑异构酶I抑制活性。 吴茱萸碱的作用是通过稳定拓扑异构酶I和DNA之间的共价复合物，导致DNA复制和转录的阻断。

    Grain germinating system
    3.
    发明授权
    Grain germinating system 有权
    谷物发芽系统

    公开(公告)号：US08683743B2

    公开(公告)日：2014-04-01

    申请号：US12728283

    申请日：2010-03-22

    申请人： Chun-Mao Lin ,  Fu-Der Mai ,  Chien-Lung Hung ,  Chwen-Ming Shih

    发明人： Chun-Mao Lin ,  Fu-Der Mai ,  Chien-Lung Hung ,  Chwen-Ming Shih

    IPC分类号： A01G31/02

    CPC分类号： G05D23/1931 ,  A01C1/02

    摘要： The present invention discloses a grain germinating system comprising a temperature controlling device, an incubation device, a drying device and a monitoring device. The temperature controlling device comprises a heat pump module, an air conditioning module and a piping module. The heat pump module can output a high or low temperature heat exchanging liquid. The temperature of a culture medium of a grain is adjusted by the incubation device. The incubated grain is dried by the drying device. The air conditioning module is for a plant building. The piping module is connected with the heat pump module, and is provided for the high or low temperature heat exchanging liquid to flow. The incubation device and the drying device are heated by the high temperature heat exchanging liquid. The drying device is cooled by the low temperature heat exchanging liquid provided for the air condition of the plant building to use.

    摘要翻译： 本发明公开了一种谷物发芽系统，包括温度控制装置，孵育装置，干燥装置和监测装置。 温度控制装置包括热泵模块，空调模块和管道模块。 热泵模块可以输出高温或低温热交换液体。 通过培养装置调节谷物培养基的温度。 通过干燥装置干燥温育的谷物。 空调模块用于厂房。 管道模块与热泵模块相连，为高温或低温热交换液体流通。 孵育装置和干燥装置由高温热交换液体加热。 干燥装置由为工厂建筑空气使用的低温热交换液体而冷却。