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公开(公告)号：US20110313277A1
公开(公告)日：2011-12-22
申请号：US13148677
申请日：2010-02-01
IPC分类号： A61B5/055
CPC分类号： A61B5/05 , A61B5/0522
摘要： This invention relates to a method and device for reconstructing images of an object of interest. According to the invention, the device comprises a plurality of transmitting coils (102, 103, 115, 116) for generating a primary magnetic field; a plurality of measurement coils (121, 122, 129, 136); and means (150) for selecting and exciting a first pair of transmitting coils (102, 116) among the plurality of transmitting coils, wherein the first pair of transmitting coils (102, 116) are selected and excited in a way such that of transmitting coils is minimized at the location of at least one measurement coil among the plurality of measurement coils (121, 129). By minimizing the primary magnetic field at the location of the measurement coil(s), the device can reduce the dynamic range of measurement coils, resulting in simplified hardware design for magnetic induction tomography systems.
摘要翻译： 本发明涉及一种重建感兴趣对象的图像的方法和装置。 根据本发明，该装置包括用于产生初级磁场的多个发射线圈（102,103,115,116）; 多个测量线圈（121,122,129,136）; 以及用于选择和激励所述多个发射线圈中的第一对发射线圈（102,116）的装置（150），其中所述第一对发射线圈（102,116）被选择和激励，使得发射线圈 线圈在多个测量线圈（121,129）中的至少一个测量线圈的位置处被最小化。 通过使测量线圈位置处的主磁场最小化，该装置可以减少测量线圈的动态范围，从而简化磁感应层析成像系统的硬件设计。
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2.发明申请COMPRESSED SENSING MR IMAGE RECONSTRUCTION USING CONSTRAINT FROM PRIOR ACQUISITION 有权使用来自先前收购的约束的压缩感测MR图像重建公开(公告)号：US20140009156A1
公开(公告)日：2014-01-09
申请号：US14006244
申请日：2012-02-28
申请人： Mariya Ivanova Doneva , Stefanie Remmele , Peter Bornert , Peter Mazurkewitz , Julien Senegas , Jochen Keupp , Kay Nehrke
发明人： Mariya Ivanova Doneva , Stefanie Remmele , Peter Bornert , Peter Mazurkewitz , Julien Senegas , Jochen Keupp , Kay Nehrke
IPC分类号： G01R33/56
CPC分类号： G01R33/56 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: subjecting the portion of the body (10) to a first imaging sequence for acquiring a first signal data set (21); subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).
摘要翻译： 本发明涉及放置在MR装置（1）的检查体积中的患者的身体（10）的至少一部分的MR成像方法，该方法包括以下步骤：对身体的部分（ 10）到用于获取第一信号数据集（21）的第一成像序列; 使所述身体（10）的所述部分经受第二成像序列以获取第二信号数据集（23），其中所述第二成像序列的成像参数与所述第一成像序列的成像参数不同; 通过使用第一信号数据集（21）的正则化作为先前信息，从第二信号数据集（23）重建MR图像。 此外，本发明涉及MR设备（1）和用于MR设备（1）的计算机程序。
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公开(公告)号：US20080230715A1
公开(公告)日：2008-09-25
申请号：US11997417
申请日：2006-07-25
申请人： Tim Nielsen , Udo Van Stevendaal , Bernhard Gleich , Tobias Schaeffter , Paul Haaker , Peter Mazurkewitz , Steffen Weiss
发明人： Tim Nielsen , Udo Van Stevendaal , Bernhard Gleich , Tobias Schaeffter , Paul Haaker , Peter Mazurkewitz , Steffen Weiss
IPC分类号： G01J1/58
CPC分类号： A61B5/0059 , A61B5/05
摘要： An optical imaging apparatus (100) for examination of an object of interest (101), the optical imaging apparatus (100) comprising an optical radiation source (102) adapted to emit a primary optical radiation beam onto the object of interest (101), an optical radiation detector (106) adapted to detect a secondary optical radiation beam emitted by the object of interest (101) upon absorbing the primary optical radiation beam, a magnetic field generating element (107) adapted to generate an inhomogeneous magnetic field varying along an extension of the object of interest (101), and a determination unit (108) adapted to determine information concerning the object of interest (101) based on an analysis of the detected secondary optical radiation beam in combination with an analysis of the inhomogeneous magnetic field.
摘要翻译： 一种用于检查感兴趣物体（101）的光学成像设备（100），所述光学成像设备（100）包括适于将主要光辐射束发射到感兴趣对象（101）上的光辐射源（102） 适于在吸收主光辐射束时检测由感兴趣物体（101）发射的次级光辐射束的光学辐射检测器（106），适于产生沿着所述第一光辐射束变化的非均匀磁场的磁场产生元件（107） 感兴趣对象的扩展（101），以及确定单元（108），其适于基于对所检测到的次级光辐射束的分析来确定与感兴趣对象（101）有关的信息，以及非均匀磁场的分析 。
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公开(公告)号：US20110133729A1
公开(公告)日：2011-06-09
申请号：US13058547
申请日：2009-08-07
IPC分类号： G01R33/14
CPC分类号： A61B5/0536 , A61B5/0522
摘要： A method and a monitoring device for performing an RF-safe MIT scan is disclosed in which it is prevented that an RF exposure, especially a specific absorption rate (SAR), imposed on an examination object, especially a patient, exceeds certain limit values during a magnetic induction tomography (MIT) scan. This is achieved on the one hand by an RF simulation method for simulating intended MIT operating parameters and calculating a resulting RF exposure of the object, and on the other hand by a monitoring device for monitoring the RF power which is applied to the object.
摘要翻译： 公开了用于执行RF安全MIT扫描的方法和监视装置，其中防止施加在检查对象，特别是患者上的RF暴露，特别是特定吸收率（SAR）超过某些限制值 磁感应断层扫描（MIT）扫描。 这一方面通过用于模拟预期的MIT操作参数并计算所得到的对象的RF曝光的RF模拟方法，另一方面由用于监视施加到对象的RF功率的监视装置来实现。
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公开(公告)号：US07362100B2
公开(公告)日：2008-04-22
申请号：US10595740
申请日：2004-11-02
申请人： Volkmar Schulz , Peter Mazurkewitz
发明人： Volkmar Schulz , Peter Mazurkewitz
IPC分类号： G01V3/00
CPC分类号： G01R33/3415
摘要： As disclosed herein, in a parallel magnetic resonance imaging method core magnetization is excited in an examination volume of a magnetic resonance (MR) device by generating at least one high frequency (HF) pulse. Two or more MR signals are recorded in parallel from the examination volume via two or more receiving channels (R, S) of the MR device using an HF coil arrangement (9), which comprises a number of coil elements (15, 16) which is greater than the number of receiving channels (R, S), wherein the respective MR signal on each receiving channel (R, S) is formed by weighted superimposition of coil signals (A, B, C, D, B) of the individual coil elements (15, 16). An MR image is reconstructed from the recorded MR signals, the MR signals being combined with one another taking into account effective spatial sensitivity profiles associated with the individual receiving channels (R, S).
摘要翻译： 如本文所公开的，在并行磁共振成像方法中，通过产生至少一个高频（HF）脉冲，磁化在磁共振（MR）装置的检查体积中被激发。 通过使用HF线圈装置（9）的MR装置的两个或多个接收通道（R，S）从检查体并行记录两个或更多个MR信号，该HF线圈装置包括多个线圈元件（15,16）， 大于接收信道数（R，S），其中每个接收信道（R，S）上的相应MR信号由个体的线圈信号（A，B，C，D，B）的加权叠加形成 线圈元件（15,16）。 从所记录的MR信号重建MR图像，考虑与各个接收信道（R，S）相关联的有效空间灵敏度分布，MR信号彼此组合。
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公开(公告)号：US20090160442A1
公开(公告)日：2009-06-25
申请号：US12295931
申请日：2007-03-15
CPC分类号： G01R33/3635 , G01R33/34046
摘要： A magnetic resonance system (8) comprises a radio frequency coil (36) which can resonate at least at first and second predetermined resonance frequencies. A tuning resonant circuit (110, 132) is serially coupled to the radio frequency coil (36). The tuning resonant circuit (110, 132) includes tuning components (Cp, Lp; Cp, Ch, Lh). Values of the tuning components (Cp, Lp; Cp, Ch, Lh) of the tuning circuit (110, 132) are selected such that a sensitivity profile of the radio frequency coil resonating at the first frequency substantially matches a sensitivity profile of the radio frequency coil resonating at the second frequency.
摘要翻译： 磁共振系统（8）包括能够至少在第一和第二预定谐振频率共振的射频线圈（36）。 调谐谐振电路（110,132）串联耦合到射频线圈（36）。 调谐谐振电路（110,132）包括调谐组件（Cp，Lp; Cp，Ch，Lh）。 选择调谐电路（110,132）的调谐分量（Cp，Lp; Cp，Ch，Lh）的值，使得以第一频率谐振的射频线圈的灵敏度曲线基本上与无线电的灵敏度分布一致 频率线圈以第二频率谐振。
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公开(公告)号：US20080077002A1
公开(公告)日：2008-03-27
申请号：US11574747
申请日：2005-09-06
申请人： Tim Nielsen , Steffen Weiss , Tobias Schaeffter , Bernhard Gleich , Paul Haaker , Udo Van Stevendaal , Peter Mazurkewitz
发明人： Tim Nielsen , Steffen Weiss , Tobias Schaeffter , Bernhard Gleich , Paul Haaker , Udo Van Stevendaal , Peter Mazurkewitz
IPC分类号： A61B5/05
CPC分类号： A61K49/225 , A61B5/0059 , A61K49/0091 , G01N21/1717 , G01N2021/6441
摘要： The present invention relates to novel methods and compounds for combined opticalultrasound imaging. The compounds of the present invention relate to particles comprising fluorescence donor and acceptor molecules for energy exchange via FRET. The methods of the present invention use ultrasound to modify the distance between donor and acceptor molecules present on the particles, and to consequently modify the fluorescence emitted by the donor and acceptor. The compounds and methods of the present invention are useful in medical or diagnostic imaging.
摘要翻译： 本发明涉及组合光超声成像的新方法和化合物。 本发明的化合物涉及通过FRET进行能量交换的包含荧光供体和受体分子的颗粒。 本发明的方法使用超声波改变存在于颗粒上的供体和受体分子之间的距离，并因此改变由供体和受体发出的荧光。 本发明的化合物和方法可用于医学或诊断成像。
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公开(公告)号：US09733328B2
公开(公告)日：2017-08-15
申请号：US14006244
申请日：2012-02-28
申请人： Mariya Ivanova Doneva , Stefanie Remmele , Peter Börnert , Peter Mazurkewitz , Julien Senegas , Jochen Keupp , Kay Nehrke
发明人： Mariya Ivanova Doneva , Stefanie Remmele , Peter Börnert , Peter Mazurkewitz , Julien Senegas , Jochen Keupp , Kay Nehrke
IPC分类号： G01R33/56 , G01R33/561 , G01R33/48 , G01R33/565
CPC分类号： G01R33/56 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: —subjecting the portion of the body (10) to a first imaging sequence for acquiring a first signal data set (21); —subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; —reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).
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公开(公告)号：US20080284435A1
公开(公告)日：2008-11-20
申请号：US10595956
申请日：2004-11-16
IPC分类号： G01R33/341
CPC分类号： G01R33/341 , G01R33/34007 , G01R33/3415
摘要： A magnetic resonance imaging system includes main magnet (20) that produces a substantially spatially and temporally constant main magnetic field within a field of view. Magnetic field gradient coils (30) impose selected magnetic field gradients on the main magnetic field within the field of view. At least one radio frequency coil (44, 44′, 44″, 144, 154) is arranged to detect a magnetic resonance signal induced by an applied radio frequency pulse. The at least one radio frequency coil includes a radio frequency antenna (90) and electronics module (78, 78′) disposed on a substrate (72). The electronics are electrically connected with the radio frequency antenna (90). The electronics are mounted in a centered region (96) surrounded by the radio frequency antenna.
摘要翻译： 磁共振成像系统包括主磁体（20），其在视场内产生基本空间和时间上恒定的主磁场。 磁场梯度线圈（30）在视野内的主磁场上施加选定的磁场梯度。 至少一个射频线圈（44,44'，44“，144,154）被布置成检测由施加的射频脉冲引起的磁共振信号。 所述至少一个射频线圈包括设置在基板（72）上的射频天线（90）和电子模块（78,78'）。 电子设备与射频天线（90）电连接。 电子装置安装在由射频天线包围的中心区域（96）中。
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公开(公告)号：US20070069727A1
公开(公告)日：2007-03-29
申请号：US10595740
申请日：2004-11-02
申请人： Volkmar Schulz , Peter Mazurkewitz
发明人： Volkmar Schulz , Peter Mazurkewitz
IPC分类号： G01V3/00
CPC分类号： G01R33/3415
摘要： The invention relates to a parallel magnetic resonance imaging method, in which core magnetization is excited in the examination volume of an MR device by generating at least one HF pulse. Two or more MR signals are then recorded in parallel from the examination volume via two or more receiving channels (R, S) of the MR device using an HF coil arrangement (9), which comprises a number of coil elements (15, 16) which is greater than the number of receiving channels (R, S), wherein the respective MR signal on each receiving channel (R, S) is formed by weighted superimposition of coil signals (A, B, C, D, E) of the individual coil elements (15, 16). Finally, according to the invention, an MR image is reconstructed from the recorded MR signals, the MR signals being combined with one another taking into account effective spatial sensitivity profiles associated with the individual receiving channels (R, S).
摘要翻译： 本发明涉及一种并行磁共振成像方法，其中通过产生至少一个HF脉冲在核磁共振器件的检查体积中激发磁化磁化。 然后通过使用HF线圈装置（9）的两个或更多个MR装置的接收通道（R，S）从检查体并行记录两个或更多个MR信号，该HF线圈装置包括多个线圈元件（15,16） 其大于接收信道（R，S）的数量，其中每个接收信道（R，S）上的相应MR信号由线圈信号（A，B，C，D，E）的加权叠加形成 单个线圈元件（15,16）。 最后，根据本发明，从所记录的MR信号重构MR图像，考虑与各个接收信道（R，S）相关联的有效空间灵敏度分布，MR信号彼此组合。
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