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公开(公告)号:US20240425827A1
公开(公告)日:2024-12-26
申请号:US18822990
申请日:2024-09-03
Applicant: Codexis, Inc.
Inventor: Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号:US10889806B2
公开(公告)日:2021-01-12
申请号:US16460147
申请日:2019-07-02
Applicant: Codexis, Inc.
Inventor: Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号:US12110513B2
公开(公告)日:2024-10-08
申请号:US17120646
申请日:2020-12-14
Applicant: Codexis, Inc.
Inventor: Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
CPC classification number: C12N9/1205 , C12Y207/01033
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号:US20200010815A1
公开(公告)日:2020-01-09
申请号:US16460147
申请日:2019-07-02
Applicant: Codexis, Inc.
Inventor: Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号:US20210102179A1
公开(公告)日:2021-04-08
申请号:US17120646
申请日:2020-12-14
Applicant: Codexis, Inc.
Inventor: Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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