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公开(公告)号：US20240425827A1
公开(公告)日：2024-12-26
申请号：US18822990
申请日：2024-09-03
Applicant: Codexis, Inc.
Inventor： Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20220162580A1
公开(公告)日：2022-05-26
申请号：US17592869
申请日：2022-02-04
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark A. Huffman , Joshua N. Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
IPC: C12N9/88
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
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公开(公告)号：US20210261940A1
公开(公告)日：2021-08-26
申请号：US17316165
申请日：2021-05-10
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20200010823A1
公开(公告)日：2020-01-09
申请号：US16460062
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant Murphy , Nicholas M. Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20250027094A1
公开(公告)日：2025-01-23
申请号：US18906502
申请日：2024-10-04
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Nikki Dellas , Vesna Mitchell , Da Duan , Jovana Nazor , Oscar Alvizo , Auric Anthony Sowell-Kantz , Jeffrey C. Moore , Mark A. Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Nicholas M. Marshall , Jay H. Russell , Keith A. Canada
IPC: C12N15/63
Abstract: The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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Patent Agency Ranking
公开(公告)号：US12110493B2
公开(公告)日：2024-10-08
申请号：US17490215
申请日：2021-09-30
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Nikki Dellas , Vesna Mitchell , Da Duan , Jovana Nazor , Oscar Alvizo , Auric Anthony Sowell-Kantz , Jeffrey C. Moore , Mark A. Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Nicholas M. Marshall , Jay H. Russell , Keith A. Canada
IPC: C12N15/63
CPC classification number: C12N15/63 , C12Y204/02001
Abstract: The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US11795445B2
公开(公告)日：2023-10-24
申请号：US17316165
申请日：2021-05-10
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
CPC classification number: C12N9/90 , C12N15/52 , C12N15/74 , C12N15/815 , C12Y504/02007
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20200010815A1
公开(公告)日：2020-01-09
申请号：US16460147
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US12110513B2
公开(公告)日：2024-10-08
申请号：US17120646
申请日：2020-12-14
Applicant: Codexis, Inc.
Inventor： Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
CPC classification number: C12N9/1205 , C12Y207/01033
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US11466259B2
公开(公告)日：2022-10-11
申请号：US16460376
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Christopher Michael Micklitsch , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , Mikayla Jianghongxia Krawczyk , Margie Tabuga Borra-Garske , Nandhitha Subramanian , Anna Fryszkowska , Nicholas M. Marshall , Agustina Rodriguez-Granillo , Deeptak Verma , Dewan Andrews
Abstract: The present invention provides engineered galactose oxidase (GOase) enzymes, polypeptides having GOase activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing GOase enzymes are also provided. The present invention further provides compositions comprising the GOase enzymes and methods of using the engineered GOase enzymes. The present invention finds particular use in the production of pharmaceutical and other compounds.
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