公开(公告)号：US11026695B2

公开(公告)日：2021-06-08

申请号：US15795083

申请日：2017-10-26

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12 ,  A61M29/00 ,  A61B17/00 ,  A61B18/14 ,  A61N7/02 ,  A61N1/39 ,  A61B18/00 ,  A61B90/00 ,  A61B17/32

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

公开(公告)号：US20200253611A1

公开(公告)日：2020-08-13

申请号：US16794006

申请日：2020-02-18

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12

摘要： Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.

公开(公告)号：US20180250014A1

公开(公告)日：2018-09-06

申请号：US15969654

申请日：2018-05-02

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan

IPC分类号： A61B17/12

CPC分类号： A61B17/12122 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/12131 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12181 ,  A61B17/1219 ,  A61B18/1492 ,  A61B2017/00004 ,  A61B2017/00022 ,  A61B2017/00221 ,  A61B2017/00526 ,  A61B2017/00853 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00951 ,  A61B2017/12054 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1495 ,  A61B2090/064 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61M29/00 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3956

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.

公开(公告)号：US20240148385A1

公开(公告)日：2024-05-09

申请号：US18486974

申请日：2023-10-13

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12 ,  A61M29/00

CPC分类号： A61B17/12122 ,  A61B17/12031 ,  A61B17/12131 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12181 ,  A61M29/00 ,  A61B2017/00951

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

公开(公告)号：US20210169500A1

公开(公告)日：2021-06-10

申请号：US17183160

申请日：2021-02-23

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12

摘要： Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame having anchors and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. A loader includes a conical portion with guides and a reservoir for submerging the foam implant prior to loading and delivery.

公开(公告)号：US20200253615A1

公开(公告)日：2020-08-13

申请号：US16794023

申请日：2020-02-18

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12

摘要： Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.

公开(公告)号：US20180116678A1

公开(公告)日：2018-05-03

申请号：US15795083

申请日：2017-10-26

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan

IPC分类号： A61B17/12 ,  A61M29/00

CPC分类号： A61B17/12122 ,  A61B17/00491 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/12131 ,  A61B17/12136 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12181 ,  A61B17/1219 ,  A61B18/1492 ,  A61B2017/00004 ,  A61B2017/00022 ,  A61B2017/00221 ,  A61B2017/00526 ,  A61B2017/00853 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00951 ,  A61B2017/12054 ,  A61B2017/320069 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2090/064 ,  A61B2090/3966 ,  A61M29/00 ,  A61M2205/04 ,  A61M2205/3331 ,  A61N1/395 ,  A61N1/39622 ,  A61N7/022

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

公开(公告)号：US20230071677A1

公开(公告)日：2023-03-09

申请号：US17896979

申请日：2022-08-26

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12 ,  A61N1/372 ,  A61N1/375 ,  A61N1/39 ,  A61B18/14

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.

公开(公告)号：US20210393271A1

公开(公告)日：2021-12-23

申请号：US17338520

申请日：2021-06-03

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12 ,  A61M29/00

摘要： Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

公开(公告)号：US11116510B2

公开(公告)日：2021-09-14

申请号：US16794006

申请日：2020-02-18

申请人： Conformal Medical, Inc.

发明人： David A. Melanson ,  Andy H. Levine ,  James H. Loper ,  Michael T. Radford ,  Carol Devellian ,  Aaron V. Kaplan ,  Ronald B. Lamport

IPC分类号： A61B17/12 ,  A61B17/00 ,  A61B90/00

摘要： Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.