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    Anthranilamides with heteroarylsulfonyl side chain, process of preparation, and use
    6.
    发明授权
    Anthranilamides with heteroarylsulfonyl side chain, process of preparation, and use 有权
    具有杂芳基磺酰侧链的邻氨基苯甲酰胺，制备方法和用途

    公开(公告)号：US07235664B2

    公开(公告)日：2007-06-26

    申请号：US11052959

    申请日：2005-02-08

    申请人： Joachim Brendel ,  Thomas Boehme ,  Stefan Peukert ,  Heinz-Werner Kleemann

    发明人： Joachim Brendel ,  Thomas Boehme ,  Stefan Peukert ,  Heinz-Werner Kleemann

    IPC分类号： C07D215/36 ,  A61K31/47

    CPC分类号： C07D261/10 ,  A61K31/47 ,  A61K45/06 ,  C07D215/36 ,  C07D217/02 ,  C07D271/12 ,  C07D333/34 ,  C07D401/12 ,  C07D405/12 ,  A61K2300/00

    摘要： This invention encompasses anthranilamides with heteroarylsulfonyl side chain, process for their preparation, their use as medicament or diagnostic aid, and pharmaceutical preparations containing them. Compounds of formula I, in which R1 to R7 have the meanings stated in the claims, act on the Kv1.5 potassium channel and inhibit a potassium current which is referred to as the ultra-rapidly activating delayed rectifier in the atrium of the human heart. They are therefore suitable as novel antiarrhythmic ingredients, such as for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillation (AF) or atrial flutter.

    摘要翻译： 本发明包括具有杂芳基磺酰侧链的邻氨基苯甲酰胺，其制备方法，它们作为药物或诊断助剂的用途，以及含有它们的药物制剂。 其中R 1至R 7具有权利要求中所述含义的式I化合物作用于Kv1.5钾通道并抑制在人心脏中心被称为超快速活化延迟整流剂的钾电流 。 因此，它们适合作为新的抗心律失常成分，例如用于治疗和预防心房心律失常，例如， 心房颤动（AF）或心房扑动。

    System and method for hierarchical layout specialization
    7.
    发明申请
    System and method for hierarchical layout specialization 失效
    分层布局专业化的系统和方法

    公开(公告)号：US20050120288A1

    公开(公告)日：2005-06-02

    申请号：US10502247

    申请日：2003-02-21

    申请人： Thomas Boehme ,  Alexandra Lieberman

    发明人： Thomas Boehme ,  Alexandra Lieberman

    IPC分类号： G06F17/21 ,  G06F13/00 ,  G06F17/30 ,  G06F21/24 ,  G06F15/00

    CPC分类号： G06F17/30873

    摘要： The present invention discloses a system and method for delegated page specialization based on a page layer concept. A page consist of a set of layers. Except the first layer each layer represents a delta (container, frames) in its layout to its previous layer introduced on the corresponding level of administration. Administrators can modify the previous layers by defining new immutable and optional containers or frames on the page (delta). Only the deltas to the previous layers are stored with assignments to their parent layers. Immutable containers or frames of previous layers cannot be modified. The final page is automatically constructed as an union of deltas being stored in a so called tree-structure. The delegated page specialization is preferably accomplished via a GUI-component which supports the administrators.

    摘要翻译： 本发明公开了一种基于页面层概念的委托页专业化的系统和方法。 页面由一组图层组成。 除了第一层之外，每个层都表示其布局中的三角形（容器，框架），其上一层在相应的管理级别上引入。 管理员可以通过在页面（delta）上定义新的不可变的和可选的容器或框架来修改先前的图层。 只有前几层的三角形才能存​​储到父层中。 不可变形的容器或先前图层的框架不能修改。 最后一页被自动构造为一个三角形的联合，存储在所谓的树结构中。 委托页专业化最好通过支持管理员的GUI组件实现。

    Method for reducing the size of computer programs
    8.
    发明授权
    Method for reducing the size of computer programs 失效
    减少计算机程序大小的方法

    公开(公告)号：US5901314A

    公开(公告)日：1999-05-04

    申请号：US697972

    申请日：1996-09-03

    申请人： Thomas Boehme ,  Juergen Uhl

    发明人： Thomas Boehme ,  Juergen Uhl

    IPC分类号： G06F9/44 ,  G06F9/45

    CPC分类号： G06F9/4433 ,  G06F8/4434

    摘要： A method of reducing the size of compiled and executable computer programs which are edited with the aid of object-oriented programming techniques. The common portions of a program produced by an object-oriented programming technique are separated as untyped implementation classes from the typed interface classes with parameterized templates where the typed interface classes comprise no virtual functions. Untyped implementation classes are arranged in a second polymorph class hierarchy, and method calls to the interface classes are delegated to the implementation classes. The invention is particularly applicable to the technical field of producing class libraries for an object-oriented programming language. The invention advantageously achieves an effective and significant reduction in the size of computer programs and thus allows the computer program to be stored and executed with less demand on the hardware requirements of the computer system.

    摘要翻译： 借助于面向对象编程技术编辑的编译和可执行计算机程序的大小减小的方法。 由面向对象编程技术生成的程序的公共部分与类型化的接口类与参数化模板分离为非类型实现类，其中类型化接口类不包含虚函数。 非类型的实现类被排列在第二个多态类层次结构中，并且将对接口类的方法调用委托给实现类。 本发明特别适用于面向对象编程语言的生成类库的技术领域。 本发明有利地实现了计算机程序的大小的有效和显着的减小，因此允许以较少的对计算机系统的硬件要求的需求来存储和执行计算机程序。