公开(公告)号：US09080054B2

公开(公告)日：2015-07-14

申请号：US14006396

申请日：2012-03-21

申请人： Craig Valentine ,  Vaughn Williams

发明人： Craig Valentine ,  Vaughn Williams

IPC分类号： C08L71/12 ,  A61L27/18 ,  A61L31/06 ,  C08L71/00 ,  B29C45/00

CPC分类号： C08L71/12 ,  A61L27/18 ,  A61L31/06 ,  B29C45/0001 ,  C08G2650/40 ,  C08L71/00 ,  Y10T29/49

摘要： A medical device comprises parts made by injection moulding and parts made by machining such that the respective parts have similar colors, measured on the L*, a*, b* scale. The parts made by injection moulding may be made in a process which involves introducing molten material comprising polymeric material such as PEEK into a mould, wherein a mould surface which contacts the molten material is at a temperature of at least 210° C. and maintaining the molten material in the mould for at least 90 seconds.

摘要翻译： 医疗装置包括通过注射成型的部件和通过机械加工制成的零件，使得各个部件具有在L *，a *，b *刻度上测量的相似颜色。 通过注射成型制成的部件可以以包括将包含聚合物材料（例如PEEK）的熔融材料引入模具的方法制造，其中与熔融材料接触的模具表面的温度至少为210℃， 熔融材料在模具中至少90秒。

公开(公告)号：US20140107299A1

公开(公告)日：2014-04-17

申请号：US14006396

申请日：2012-03-21

申请人： Craig Valentine ,  Vaughn Williams

发明人： Craig Valentine ,  Vaughn Williams

IPC分类号： A61L31/06 ,  B29C45/00

CPC分类号： C08L71/12 ,  A61L27/18 ,  A61L31/06 ,  B29C45/0001 ,  C08G2650/40 ,  C08L71/00 ,  Y10T29/49

摘要： A medical device comprises parts made by injection moulding and parts made by machining such that the respective parts have similar colours, measured on the L*, a*, b* scale. The parts made by injection moulding may be made in a process which involves introducing molten material comprising polymeric material such as PEEK into a mould, wherein a mould surface which contacts the molten material is at a temperature of at least 210° C. and maintaining the molten material in the mould for at least 90 seconds.

摘要翻译： 医疗装置包括通过注射成型的部件和通过机械加工制成的零件，使得各个部件具有在L *，a *，b *刻度上测量的相似颜色。 通过注射成型制成的部件可以以包括将包含聚合物材料（例如PEEK）的熔融材料引入模具中的方法制成，其中与熔融材料接触的模具表面处于至少210℃的温度， 熔融材料在模具中至少90秒。

公开(公告)号：US20140200466A1

公开(公告)日：2014-07-17

申请号：US14128686

申请日：2012-06-21

申请人： Nuno Sereno ,  Vaughn Williams ,  Marcus Jarman-Smith ,  Nikolaj Gadegaard

发明人： Nuno Sereno ,  Vaughn Williams ,  Marcus Jarman-Smith ,  Nikolaj Gadegaard

IPC分类号： A61L31/06 ,  A61N1/36 ,  A61B5/00

CPC分类号： A61L31/06 ,  A61B5/6869 ,  A61L27/18 ,  A61N1/36 ,  C08G2650/40 ,  C08L71/00 ,  C08L81/06 ,  Y10T428/24479

摘要： Topographical features, such as projections or recesses, having a maximum dimension which is less than 3 μm, with the features being separated by a distance which is less than 10 μm are transferred to polyetheretherketone, on an industrial scale, by injection moulding relatively low viscosity PEEK, using a mould in which is arranged a master structure which carries the desired topography. The topographical features increase the water contact angle of a surface which includes them and such a modified surface has been shown to influence cell attachment and differentiation. Parts which incorporate the topographical features may be used in medical devices such as implantable medical devices for cardiology or for neuromodulation.

摘要翻译： 具有小于3μm的最大尺寸的形状特征，例如具有小于10μm的距离的特征被放置在工业规模上，通过注塑相对低的粘度转移到聚醚醚酮 PEEK，使用其中布置有携带所需形貌的主结构的模具。 形貌特征增加包括它们的表面的水接触角，并且已经显示这种改性表面影响细胞附着和分化。 结合地形特征的部件可以用于诸如用于心脏病学的植入式医疗装置或用于神经调节的医疗装置中。