公开(公告)号：US20240197857A1

公开(公告)日：2024-06-20

申请号：US18596451

申请日：2024-03-05

申请人： CureVac SE

发明人： Karl-Josef KALLEN ,  Thomas KRAMPS ,  Margit SCHNEE ,  Benjamin PETSCH ,  Lothar STITZ

IPC分类号： A61K39/145 ,  A61K39/00 ,  A61K39/12 ,  A61K45/06 ,  C12N7/00

CPC分类号： A61K39/145 ,  A61K39/00 ,  A61K39/0011 ,  A61K39/12 ,  A61K45/06 ,  C12N7/00 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/55 ,  A61K2039/55505 ,  A61K2039/5555 ,  A61K2039/55555 ,  A61K2039/572 ,  A61K2039/585 ,  A61K2039/6031 ,  A61K2039/622 ,  A61K2039/70 ,  C12N2760/16134 ,  Y02A50/30

摘要： The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in an elderly patient preferably exhibiting an age of at least 50 years, more preferably of at least 55 years, 60 years, 65 years, 70 years, or older, wherein the treatment comprises vaccination of the patient and eliciting an immune response in said patient. The present invention is furthermore directed to kits and kits of parts comprising such a vaccine and/or its components and to methods applying such a vaccine or kit.

公开(公告)号：US20230233662A1

公开(公告)日：2023-07-27

申请号：US18299676

申请日：2023-04-12

申请人： CureVac SE

发明人： Karl-Josef KALLEN ,  Thomas KRAMPS ,  Margit SCHNEE ,  Benjamin PETSCH ,  Lothar STITZ

IPC分类号： A61K39/155 ,  A61K39/12 ,  A61K39/145 ,  A61K47/59 ,  A61K47/64 ,  A61K47/69 ,  A61P31/16 ,  A61K39/00 ,  A61K45/06

CPC分类号： A61K39/155 ,  A61K39/12 ,  A61K39/145 ,  A61K47/59 ,  A61K47/6455 ,  A61K47/6921 ,  A61P31/16 ,  A61K39/00 ,  A61K45/06 ,  A61K2039/53 ,  A61K2039/55 ,  A61K2039/572 ,  C12N2760/16134 ,  Y02A50/30 ,  A61K2039/54 ,  A61K2039/55583 ,  A61K2039/575 ,  A61K2039/6031 ,  A61K2039/622 ,  C12N2760/18534 ,  C12N2760/18571

摘要： The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in newborns and/or infants, preferably exhibiting an age of not more than 2 years, preferably of not more than 1 year, more preferably of not more than 9 months or even 6 months, wherein the treatment comprises vaccination of the newborn or infant and eliciting an immune response in said newborn or infant. The present invention is furthermore directed to kits and kits of parts comprising such a vaccine and/or its components and to methods applying such a vaccine or kit.