公开(公告)号：US08637233B2

公开(公告)日：2014-01-28

申请号：US13464936

申请日：2012-05-04

申请人： Cynthia S. Nickel ,  Clois E. Powell ,  James R. Biard ,  William A. Stapleton ,  Gary M. Aron ,  Jeanette Hill ,  Ray G. Cook ,  Daniel M. Justiss ,  Frederick J. Strieter ,  Wayne T. Kilian ,  Andrei M. Manoliu

发明人： Cynthia S. Nickel ,  Clois E. Powell ,  James R. Biard ,  William A. Stapleton ,  Gary M. Aron ,  Jeanette Hill ,  Ray G. Cook ,  Daniel M. Justiss ,  Frederick J. Strieter ,  Wayne T. Kilian ,  Andrei M. Manoliu

IPC分类号： C12Q1/00

CPC分类号： C12Q1/18 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/0645 ,  C12Q1/02 ,  C12Q1/04 ,  G01N15/0656 ,  G01N33/48735

摘要： A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.

摘要翻译： 确定试剂的抗微生物活性的方法可以包括提供井，其中所述井含有至少一种抗微生物剂，所述井还包括至少两个电极。 可以将微量的样品加入阱中，并在电极之间施加脉冲电压。 可以对电气特性进行采样和记录。 在另一方面，鉴定至少一种微生物的方法包括取包含所述至少一种微生物的样品，从所述样品中分离所述至少一种微生物，将所述至少一种微生物分成至少一种孔，其中每个孔含有 至少一种抗微生物剂和至少两种电极。 在至少两个电极之间脉冲电压，在脉冲期间对电性质进行采样并记录。 在另一方面，提供了用于检测至少一个微生物的诊断装置。

公开(公告)号：US20130017534A1

公开(公告)日：2013-01-17

申请号：US13464936

申请日：2012-05-04

申请人： Cynthia S. Nickel ,  Clois E. Powell ,  James R. Biard ,  William A. Stapleton ,  Gary M. Aron ,  Jeanette Hill ,  Ray G. Cook ,  Daniel M. Justiss ,  Frederick J. Strieter ,  Wayne T. Kilian ,  Andrei M. Manoliu

发明人： Cynthia S. Nickel ,  Clois E. Powell ,  James R. Biard ,  William A. Stapleton ,  Gary M. Aron ,  Jeanette Hill ,  Ray G. Cook ,  Daniel M. Justiss ,  Frederick J. Strieter ,  Wayne T. Kilian ,  Andrei M. Manoliu

IPC分类号： G01N27/26 ,  C12M1/42

CPC分类号： C12Q1/18 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/0645 ,  C12Q1/02 ,  C12Q1/04 ,  G01N15/0656 ,  G01N33/48735

摘要： A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.

摘要翻译： 确定试剂的抗微生物活性的方法可以包括提供井，其中所述井含有至少一种抗微生物剂，所述井还包括至少两个电极。 可以将微量的样品加入阱中，并在电极之间施加脉冲电压。 可以对电气特性进行采样和记录。 在另一方面，鉴定至少一种微生物的方法包括取包含所述至少一种微生物的样品，从所述样品中分离所述至少一种微生物，将所述至少一种微生物分成至少一种孔，其中每个孔含有 至少一种抗微生物剂和至少两种电极。 在至少两个电极之间脉冲电压，在脉冲期间对电性质进行采样并记录。 在另一方面，提供了用于检测至少一个微生物的诊断装置。

公开(公告)号：US20130183459A1

公开(公告)日：2013-07-18

申请号：US13715800

申请日：2012-12-14

申请人： Cynthia S. Nickel ,  Clois E. Powell

发明人： Cynthia S. Nickel ,  Clois E. Powell

IPC分类号： B05D5/12

CPC分类号： B05D5/12 ,  C12Q1/04 ,  C12Q1/18 ,  G01N15/0656 ,  G01N27/308 ,  G01N33/48735

摘要： A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.

公开(公告)号：US20080165004A1

公开(公告)日：2008-07-10

申请号：US11666236

申请日：2005-10-26

申请人： James Thomas Edward McDonnell ,  Cynthia S. Nickel ,  David Neil Slatter

发明人： James Thomas Edward McDonnell ,  Cynthia S. Nickel ,  David Neil Slatter

IPC分类号： G08B13/14

CPC分类号： G06K19/07726 ,  G06K19/073 ,  G06K19/07327 ,  G06K19/07749

摘要： A packaged product comprises a physical product, an inductively powered transponder device having a memory containing digital content, and a packaging. The packaging is adapted to prevent sufficient signal from reaching an antenna of the inductively powered transponder device to enable the digital content to be read from the memory.

摘要翻译： 包装产品包括物理产品，具有包含数字内容的存储器的感应供电的应答器设备和包装。 该封装适于防止足够的信号到达感应供电的应答器设备的天线，以便能够从存储器读取数字内容。