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公开(公告)号:US08093237B2
公开(公告)日:2012-01-10
申请号:US12047858
申请日:2008-03-13
申请人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
发明人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
IPC分类号: A61P25/00 , A61K31/553 , C07D267/02
CPC分类号: C07D413/04 , C07D405/14 , C07D453/02
摘要: The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4 ]oxazapine compounds of the formula: where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of preparing these compounds are also described. These compounds may be used in the treatment of disorders such as schizophrenia, treatment resistant schizophrenia, bipolar disorder, psychotic depression, treatment resistant depression, schizophrenia-associated depression, treatment resistant OCD, autism, senile psychosis, psychotic dementia, L-DOPA induced psychosis, psychogenic polydipsia, psychotic symptoms of neurological disorders, sleep disorders.
摘要翻译: 本发明涉及下式的11-(哌嗪-1-基)二苯并[b,f] [1,4]恶唑氮化合物:其中变量如本文所定义,其盐和药学上可接受的组合物。 还描述了制备这些化合物的方法。 这些化合物可用于治疗精神分裂症,治疗耐药性精神分裂症,双相性精神障碍,精神病抑郁症,治疗耐药性抑郁症,精神分裂症相关抑郁症,治疗耐药性OCD,孤独症,老年性精神病,精神病性痴呆,L-DOPA诱发的精神病 ,心理性多饮,精神病性神经障碍症状,睡眠障碍。
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公开(公告)号:US20120178738A1
公开(公告)日:2012-07-12
申请号:US13323183
申请日:2011-12-12
申请人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
发明人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
IPC分类号: A61K31/553 , A61P25/18 , A61P25/22 , A61P25/00 , A61P25/28 , C07D413/04 , A61P25/24
CPC分类号: C07D413/04 , C07D405/14 , C07D453/02
摘要: The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazapine compounds of the formula: where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of preparing these compounds are also described. These compounds may be used in the treatment of disorders such as schizophrenia, treatment resistant schizophrenia, bipolar disorder, psychotic depression, treatment resistant depression, schizophrenia-associated depression, treatment resistant OCD, autism, senile psychosis, psychotic dementia, L-DOPA induced psychosis, psychogenic polydipsia, psychotic symptoms of neurological disorders, sleep disorders.
摘要翻译: 本发明涉及下式的11-(哌嗪-1-基)二苯并[b,f] [1,4]恶唑氮化合物:其中变量如本文所定义,其盐和药学上可接受的组合物。 还描述了制备这些化合物的方法。 这些化合物可用于治疗精神分裂症,治疗耐药性精神分裂症,双相性精神障碍,精神病抑郁症,治疗耐药性抑郁症,精神分裂症相关抑郁症,治疗耐药性OCD,孤独症,老年性精神病,精神病性痴呆,L-DOPA诱发的精神病 ,心理性多饮,精神病性神经障碍症状,睡眠障碍。
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公开(公告)号:US20080255088A1
公开(公告)日:2008-10-16
申请号:US12047858
申请日:2008-03-13
申请人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
发明人: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
IPC分类号: A61K31/553 , C07D267/08 , A61P25/18
CPC分类号: C07D413/04 , C07D405/14 , C07D453/02
摘要: The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazapine compounds of the formula: where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of preparing these compounds are also described. These compounds may be used in the treatment of disorders such as schizophrenia, treatment resistant schizophrenia, bipolar disorder, psychotic depression, treatment resistant depression, schizophrenia-associated depression, treatment resistant OCD, autism, senile psychosis, psychotic dementia, L-DOPA induced psychosis, psychogenic polydipsia, psychotic symptoms of neurological disorders, sleep disorders.
摘要翻译: 本发明涉及下式的11-(哌嗪-1-基)二苯并[b,f] [1,4]恶唑氮化合物:其中变量如本文所定义,其盐和药学上可接受的组合物。 还描述了制备这些化合物的方法。 这些化合物可用于治疗精神分裂症,治疗耐药性精神分裂症,双相性精神障碍,精神病抑郁症,治疗耐药性抑郁症,精神分裂症相关抑郁症,治疗耐药性OCD,孤独症,老年性精神病,精神病性痴呆,L-DOPA诱发的精神病 ,心理性多饮,精神病性神经障碍症状,睡眠障碍。
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公开(公告)号:US20110295627A1
公开(公告)日:2011-12-01
申请号:US12790549
申请日:2010-05-28
申请人: Jason P. Lampe , Jason Adams , Douglas W. Belew , Xiaoling Cai , Paul Chambless , Jeffrey B. Myers , Jesse L. Nelson , Paul R. Shellum
发明人: Jason P. Lampe , Jason Adams , Douglas W. Belew , Xiaoling Cai , Paul Chambless , Jeffrey B. Myers , Jesse L. Nelson , Paul R. Shellum
CPC分类号: G06Q30/0635 , G06Q10/063 , G06Q10/087
摘要: An ordering system backend includes an ordering system module, an exclusion system module, an exception system module, a summary system module, and a display device. The ordering system module is configured to receive ordering data for a plurality of orders and to receive information concerning the flowthrough status of the order. The exclusion system module is configured to generate or receive a plurality of exclusions associated with a plurality of exceptions for the plurality of orders. The exception system module is configured to generate or receive exception data associated with the plurality of orders, to receive the plurality of exclusions from the exclusion system module, and to update the exception data based on the plurality of exclusions. The summary system module is configured to calculate summary level data based on the plurality of orders and the exception data, and to create summary tables based on the summary level data. The display device includes a graphical user interface configured to display the summary tables.
摘要翻译: 订购系统后端包括订购系统模块,排除系统模块,异常系统模块,汇总系统模块和显示设备。 订购系统模块被配置为接收多个订单的订购数据并且接收关于订单的流通状态的信息。 排除系统模块被配置为生成或接收与多个订单的多个异常相关联的多个排除。 异常系统模块被配置为生成或接收与多个订单相关联的异常数据,以从排除系统模块接收多个排除,并且基于多个排除来更新异常数据。 汇总系统模块被配置为基于多个订单和异常数据计算汇总水平数据,并且基于汇总水平数据创建汇总表。 显示设备包括被配置为显示汇总表的图形用户界面。
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公开(公告)号:US20100101405A1
公开(公告)日:2010-04-29
申请号:US12644436
申请日:2009-12-22
申请人: Jason Adams
发明人: Jason Adams
CPC分类号: F41A5/26 , F41A11/00 , Y10T29/49815
摘要: A direct drive retrofit system for use with an M-16 or AR-15 rifle for conversion from an impingement system comprising: a gas block, the gas block having a barrel bore and a gas plug bore; a gas plug, the gas plug being inserted into the gas plug bore from the muzzle end; a bolt carrier key, the bolt carrier key being configured to mount directly to a bolt carrier; a rod, the rod being manufactured from a single continuous material stock; and a biasing means; wherein, the rod can be uninstalled without removal of a hand guard or the gas block by extracting the gas plug from the gas plug bore from the muzzle end, the actuating means releasing the rod, the rod being freely extracted thereafter by a user in a single piece.
摘要翻译: 一种与用于从冲击系统转换的M-16或AR-15步枪一起使用的直接驱动改造系统,包括:气块,气块具有筒孔和气塞孔; 气塞,气塞从枪口端插入气塞孔中; 螺栓承载钥匙,所述螺栓承载钥匙被配置为直接安装到螺栓承载件; 杆,杆由单一连续材料原料制成; 和偏置装置; 其中,可以通过从枪口端从气塞孔提取气塞而不用去除手指或气块来卸载杆,所述致动装置释放杆,杆随后由使用者自动抽出 单件
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公开(公告)号:US20060032356A1
公开(公告)日:2006-02-16
申请号:US10918609
申请日:2004-08-12
申请人: Robert Newman , Jason Adams
发明人: Robert Newman , Jason Adams
IPC分类号: B23D45/02
CPC分类号: B23D45/046 , B23D59/001 , B27B5/075 , Y10T83/7693 , Y10T83/7763 , Y10T83/7768 , Y10T83/7784
摘要: A panel saw has a first cutting blade for cutting stock in a first axis and a second cutting blade for cutting the stock in a second axis. The first blade moveable from a cutting position to a position in which stock can be slid between the cutting blade and a supporting frame of the panel saw. The panel saw allows repeated cross cuts and rip cuts without changing the cutting location of the first cutting blade. A control system is configured to retract the first cutting blade from contact with the stock if the current draw exceeds a value. The control system may also retract a cutting blade when it senses the end of a panel being cut.
摘要翻译: 板锯具有用于在第一轴线上切割坯料的第一切割刀片和用于在第二轴线上切割坯料的第二切割刀片。 第一刀片可从切割位置移动到库存可在切割刀片和面板锯的支撑框架之间滑动的位置。 面板锯允许重复的横切和撕裂切割而不改变第一切割刀片的切割位置。 控制系统被配置为如果电流消耗超过一个值,则使第一切割刀片不与库存接触。 当控制系统感测切割的面板的端部时,还可以缩回切割刀片。
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公开(公告)号:US07469624B1
公开(公告)日:2008-12-30
申请号:US11938678
申请日:2007-11-12
申请人: Jason Adams
发明人: Jason Adams
IPC分类号: F41A5/00
CPC分类号: F41A5/26 , F41A11/00 , Y10T29/49815
摘要: A direct drive retrofit system for use with an M-16 or AR-15 rifle for conversion from an impingement system comprising: a gas block, the gas block having a barrel bore and a gas plug bore; a gas plug, the gas plug being inserted into the gas plug bore from the muzzle end; a bolt carrier key, the bolt carrier key being configured to mount directly to a bolt carrier; a rod, the rod being manufactured from a single continuous material stock; and a biasing means; wherein, the rod can be uninstalled without removal of a hand guard or the gas block by extracting the gas plug from the gas plug bore from the muzzle end, the actuating means releasing the rod, the rod being freely extracted thereafter by a user in a single piece.
摘要翻译: 一种与用于从冲击系统转换的M-16或AR-15步枪一起使用的直接驱动改造系统,包括:气块,气块具有筒孔和气塞孔; 气塞,气塞从枪口端插入气塞孔中; 螺栓承载钥匙,所述螺栓承载钥匙被配置为直接安装到螺栓承载件; 杆,杆由单一连续材料原料制成; 和偏置装置; 其中,可以通过从枪口端从气塞孔提取气塞而不用去除手指或气块来卸载杆,所述致动装置释放杆,杆随后由使用者自动抽出 单件
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公开(公告)号:US20050077163A1
公开(公告)日:2005-04-14
申请号:US10686387
申请日:2003-10-14
申请人: Jason Adams , Gregory Altonen , Glenn Bowers , Scott Kleppinger , Nicole Vigue
发明人: Jason Adams , Gregory Altonen , Glenn Bowers , Scott Kleppinger , Nicole Vigue
CPC分类号: H01H13/60
摘要: A switch assembly includes an actuator assembly having a slidably supported pushbutton and a switch mechanism switchable between alternate positions. The pushbutton is biased by a return spring between the pushbutton and a retainer. A pin is received within the return spring coils and engages a pivot member through an elongated opening in the retainer that allows lateral pin movement. A switch plate moves between alternate positions by contact with the pivot member and is maintained in one of the positions by a contact spring between the pivot member and plate. A spring damper in the contact spring coils limits resonating vibration. The switch assembly provides a multiple segment force input profile having first and second segments leading to the switching force with slopes according to a preferred ratio. Third and fourth segments of the input profile following the switching force define a V-shape.
摘要翻译: 开关组件包括具有可滑动支撑的按钮的致动器组件和可在替换位置之间切换的开关机构。 按钮由按钮和保持器之间的复位弹簧偏置。 一个销被接收在回弹弹簧圈内,并通过允许横向销移动的保持器中的细长开口接合枢轴件。 开关板通过与枢转构件接触而在交替位置之间移动,并且通过枢转构件和板之间的接触弹簧保持在一个位置。 接触弹簧圈中的弹簧阻尼器限制共振振动。 开关组件提供具有第一和第二段的多段力输入轮廓,其根据优选的比例导致具有斜率的切换力。 在切换力之后的输入轮廓的第三和第四段限定V形。
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公开(公告)号:US08756088B2
公开(公告)日:2014-06-17
申请号:US12790549
申请日:2010-05-28
申请人: Jason P. Lampe , Jason Adams , Douglas W. Belew , Xiaoling Cai , Paul Chambless , Jeffrey B. Myers , Jesse L. Nelson , Paul R. Shellum
发明人: Jason P. Lampe , Jason Adams , Douglas W. Belew , Xiaoling Cai , Paul Chambless , Jeffrey B. Myers , Jesse L. Nelson , Paul R. Shellum
IPC分类号: G06Q10/00
CPC分类号: G06Q30/0635 , G06Q10/063 , G06Q10/087
摘要: An ordering system backend includes an ordering system module, an exclusion system module, an exception system module, a summary system module, and a display device. The ordering system module is configured to receive ordering data for a plurality of orders and to receive information concerning the flowthrough status of the order. The exclusion system module is configured to generate or receive a plurality of exclusions associated with a plurality of exceptions for the plurality of orders. The exception system module is configured to generate or receive exception data associated with the plurality of orders, to receive the plurality of exclusions from the exclusion system module, and to update the exception data based on the plurality of exclusions. The summary system module is configured to calculate summary level data based on the plurality of orders and the exception data, and to create summary tables based on the summary level data. The display device includes a graphical user interface configured to display the summary tables.
摘要翻译: 订购系统后端包括订购系统模块,排除系统模块,异常系统模块,汇总系统模块和显示设备。 订购系统模块被配置为接收多个订单的订购数据并且接收关于订单的流通状态的信息。 排除系统模块被配置为生成或接收与多个订单的多个异常相关联的多个排除。 异常系统模块被配置为生成或接收与多个订单相关联的异常数据,以从排除系统模块接收多个排除,并且基于多个排除来更新异常数据。 汇总系统模块被配置为基于多个订单和异常数据计算汇总水平数据,并且基于汇总水平数据创建汇总表。 显示设备包括被配置为显示汇总表的图形用户界面。
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公开(公告)号:US20130023834A1
公开(公告)日:2013-01-24
申请号:US13557026
申请日:2012-07-24
申请人: Brandon Turner , John Burns , Dan Benzon , Adam burnight , Brian Highley , Jason Adams , Kraig Kooiman , Clint Taylor
发明人: Brandon Turner , John Burns , Dan Benzon , Adam burnight , Brian Highley , Jason Adams , Kraig Kooiman , Clint Taylor
IPC分类号: A61M5/00
CPC分类号: A61M5/1582 , A61K9/0019 , A61K9/0021 , A61M5/158 , A61M5/162 , A61M5/16804 , A61M5/3202 , A61M39/04 , A61M2005/1581 , A61M2005/1587
摘要: Fluid delivery devices, systems and methods. The fluid delivery devices may be used to delivery fluid (e.g., insulin) to a user. The devices may have one or more inlets, and may be configured for use with an injection device, such as a syringe, and/or with a pump.
摘要翻译: 流体输送装置,系统和方法。 流体输送装置可以用于向使用者输送流体(例如胰岛素)。 装置可以具有一个或多个入口,并且可以被配置为与注射装置(例如注射器)和/或与泵一起使用。
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