公开(公告)号：US20230084707A1

公开(公告)日：2023-03-16

申请号：US17714032

申请日：2022-04-05

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Narihiro TODA ,  Yusuke OTA ,  Fuminao DOI ,  Masaki MEGURO ,  Ichiro HAYAKAWA ,  Shinji ASHIDA ,  Takeshi MASUDA ,  Takashi NAKADA ,  Mitsuhiro IWAMOTO ,  Naoya HARADA ,  Tomoko TERAUCHI ,  Daisuke OKAJIMA ,  Kensuke NAKAMURA ,  Hiroaki UCHIDA ,  Hirofumi HAMADA

IPC分类号： A61K47/68 ,  A61P35/00 ,  C07K16/30 ,  C07D487/04

摘要： The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.

公开(公告)号：US20220125943A1

公开(公告)日：2022-04-28

申请号：US17543697

申请日：2021-12-06

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Narihiro TODA ,  Yusuke OTA ,  Fuminao DOI ,  Masaki MEGURO ,  Ichiro HAYAKAWA ,  Shinji ASHIDA ,  Takeshi MASUDA ,  Takashi NAKADA ,  Mitsuhiro IWAMOTO ,  Naoya HARADA ,  Tomoko TERAUCHI ,  Daisuke OKAJIMA ,  Kensuke NAKAMURA ,  Hiroaki UCHIDA ,  Hirofumi HAMADA

IPC分类号： A61K47/68 ,  A61P35/00 ,  C07D487/04 ,  C07K16/30

摘要： The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.

公开(公告)号：US20220168440A1

公开(公告)日：2022-06-02

申请号：US17442605

申请日：2020-03-24

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Narihiro TODA ,  Yusuke OTA ,  Fuminao DOI ,  Masaki MEGURO ,  Ichiro HAYAKAWA ,  Shinji ASHIDA ,  Takeshi MASUDA ,  Takashi NAKADA

IPC分类号： A61K47/68 ,  C07D519/00 ,  A61P35/00

摘要： A novel antibody-pyrrolobenzodiazepine (PBD) derivative conjugate, a medicine having therapeutic effect against tumor with the antibody-drug conjugate, and a method for treating a tumor by using the antibody-drug conjugate or medicine.

公开(公告)号：US20220395579A1

公开(公告)日：2022-12-15

申请号：US17849688

申请日：2022-06-26

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Narihiro TODA ,  Yusuke OTA ,  Fuminao DOI ,  Masaki MEGURO ,  Ichiro HAYAKAWA ,  Shinji ASHIDA ,  Takeshi MASUDA ,  Takashi NAKADA ,  Mitsuhiro IWAMOTO ,  Naoya HARADA ,  Tomoko TERAUCHI ,  Daisuke OKAJIMA ,  Kensuke NAKAMURA ,  Hiroaki UCHIDA ,  Hirofumi HAMADA

IPC分类号： A61K47/68 ,  A61P35/00 ,  C07D487/04 ,  C07K16/30

摘要： The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.

公开(公告)号：US20200261594A1

公开(公告)日：2020-08-20

申请号：US16651501

申请日：2018-09-28

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Narihiro TODA ,  Yusuke OTA ,  Fuminao DOI ,  Masaki MEGURO ,  Ichiro HAYAKAWA ,  Shinji ASHIDA ,  Takeshi MASUDA ,  Takashi NAKADA ,  Mitsuhiro IWAMOTO ,  Naoya HARADA ,  Tomoko TERAUCHI ,  Daisuke OKAJIMA ,  Kensuke NAKAMURA ,  Hiroaki UCHIDA ,  Hirofumi HAMADA

IPC分类号： A61K47/68 ,  C07D487/04 ,  C07K16/30 ,  A61P35/00

摘要： The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.