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公开(公告)号：US20240327784A1
公开(公告)日：2024-10-03
申请号：US18741314
申请日：2024-06-12
发明人： Mami Horiuchi , Toshiyuki Akachi , Takashi Kawada , Ryoji Fujii , Ikko Kawashima , Keita Tanaka
IPC分类号： C12N5/00
CPC分类号： C12N5/0018 , C12N2500/24
摘要： A method of producing a culture solution for human or animal cell culture includes bringing an iron supply source including an iron-containing section and a plating layer provided thereon into contact with an aqueous medium to supply iron from the iron supply source to the aqueous medium.
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公开(公告)号：US11819846B2
公开(公告)日：2023-11-21
申请号：US17952513
申请日：2022-09-26
申请人： Integriculture Inc.
发明人： Yuki Hanyu , Ikko Kawashima
CPC分类号： B01L3/502715 , B01L3/50273 , C12M1/00 , C12M3/00 , C12N5/0018 , G16B50/00 , B01L2300/087 , B01L2400/04 , C12N2501/20
摘要： In order to induce aging while cutting the costs associated with adding cytokines at different aging stages, in a system for aging induction including a first culture chamber for perfusing, with a culture medium, a subject of aging-induction, the subject of aging-induction being derived from a living organism; a second culture chamber for perfusing, with a culture medium, a secretor that secretes a cytokine; and a control device for aging induction including a detection unit, a memory unit and a control unit, a protocol for aging induction defining a procedure of aging induction is stored, and in the control unit, an aging state of the subject of aging-induction is detected with a detection unit, and based on the protocol for aging induction, a flow rate at which the culture medium containing the cytokine secreted by the secretor is supplied to the subject of aging-induction is controlled according to the aging state of the subject of aging-induction.
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公开(公告)号：US11484879B2
公开(公告)日：2022-11-01
申请号：US16098232
申请日：2016-06-13
申请人： Integriculture Inc.
发明人： Yuki Hanyu , Ikko Kawashima
摘要： In order to induce aging while cutting the costs associated with adding cytokines at different aging stages, in a system for aging induction including a first culture chamber for perfusing, with a culture medium, a subject of aging-induction, the subject of aging-induction being derived from a living organism; a second culture chamber for perfusing, with a culture medium, a secretor that secretes a cytokine; and a control device for aging induction including a detection unit, a memory unit and a control unit, a protocol for aging induction defining a procedure of aging induction is stored, and in the control unit, an aging state of the subject of aging-induction is detected with a detection unit, and based on the protocol for aging induction, a flow rate at which the culture medium containing the cytokine secreted by the secretor is supplied to the subject of aging-induction is controlled according to the aging state of the subject of aging-induction.
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