IDENTIFICATION AND CHARACTERIZATION OF THE SPINACTIN BIOSYSNTHESIS GENE CLUSTER FROM SPINOSYN PRODUCING SACCHAROPOLYSPORA SPINOSA
    4.
    发明申请
    IDENTIFICATION AND CHARACTERIZATION OF THE SPINACTIN BIOSYSNTHESIS GENE CLUSTER FROM SPINOSYN PRODUCING SACCHAROPOLYSPORA SPINOSA 有权
    来自生产SACCHAROPOLYSPORA SPINOSA的螺旋体生物化学基因簇的鉴定和表征

    公开(公告)号:US20130172215A1

    公开(公告)日:2013-07-04

    申请号:US13713586

    申请日:2012-12-13

    IPC分类号: C12N15/74

    CPC分类号: C12N15/74 C12N15/52 C12P19/62

    摘要: This disclosure concerns methods for producing a spinosyn producing strain that comprises modifying a nucleic acid molecule encoding for spinactin by introducing, mutating, deleting, replacing or inactivating a nucleic acid sequence encoding one or more activities encoded by said nucleic acid molecule. Methods for producing a modified Saccharopolyspora spinosa organism are also disclosed.

    摘要翻译: 本公开涉及用于产生多杀菌素生产菌株的方法,其包括通过引入,突变,缺失,替换或失活编码由所述核酸分子编码的一种或多种活性的核酸序列来修饰编码激肽的核酸分子。 还公开了用于生产改良的多孢子虫多糖的生物体的方法。