公开(公告)号：US20160022550A1

公开(公告)日：2016-01-28

申请号：US14775020

申请日：2014-03-14

Applicant: DSM IP ASSETS B.V.

Inventor： Jochen WEISS ,  Christiane MAIER ,  Bruno LEUENBERGER ,  Markus NOVOTNY ,  Concetta TEDESCHI ,  Anne KESSLER

IPC: A61K8/02 ,  A23L1/035 ,  A23K1/16 ,  A61K8/31 ,  A61Q19/00 ,  A61K8/55 ,  A61K8/97 ,  A61K8/24 ,  A23L1/00 ,  A61K8/67

CPC classification number: A61K8/0241 ,  A23K20/158 ,  A23L29/10 ,  A23P10/30 ,  A23V2002/00 ,  A61K8/24 ,  A61K8/31 ,  A61K8/37 ,  A61K8/553 ,  A61K8/671 ,  A61K8/97 ,  A61K2800/10 ,  A61K2800/413 ,  A61K2800/52 ,  A61K2800/651 ,  A61K2800/652 ,  A61K2800/654 ,  A61Q19/00

Abstract: The present invention relates to new (foodgrade) solid lipid nanoparticles, as well as the production of such solid lipid nanoparticles and the use of them.

Abstract translation: 本发明涉及新的（食用级）固体脂质纳米颗粒，以及这种固体脂质纳米颗粒的生产及其用途。

公开(公告)号：US20170157054A1

公开(公告)日：2017-06-08

申请号：US15440630

申请日：2017-02-23

Applicant: DSM IP ASSETS B.V.

Inventor： Markus BECK ,  Hansjoerg GRASS ,  Bruno LEUENBERGER ,  Markus NOWOTNY ,  Christian SCHÄFER ,  Karl Manfred VOELKER

IPC: A61K9/20 ,  A61K31/01 ,  A23L33/155 ,  A23K20/179 ,  A23L5/44 ,  A61K31/047 ,  A23K20/174

CPC classification number: A61K9/2081 ,  A23K20/174 ,  A23K20/179 ,  A23L5/44 ,  A23L33/155 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/31 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2059 ,  A61K31/01 ,  A61K31/047 ,  A61K2800/52 ,  A61K2800/56 ,  A61Q19/00

Abstract: The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E 1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.

公开(公告)号：US20210236431A1

公开(公告)日：2021-08-05

申请号：US17237976

申请日：2021-04-22

Applicant: DSM IP ASSETS B.V.

Inventor： Jihane ACHKAR ,  Sylvain DIGUET ,  Bruno LEUENBERGER ,  Loni SCHWEIKERT ,  Olivia VIDONI

IPC: A61K9/20 ,  A61K9/50 ,  A61K31/015 ,  A61K31/047 ,  A61K31/07 ,  A61K31/122 ,  A61K31/197 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/675 ,  A61K31/714 ,  A61K33/00 ,  A61K33/04 ,  A61K33/06 ,  A61K33/18 ,  A61K33/26 ,  A61K33/30 ,  A61K33/34

Abstract: The present patent application relates a process for the production of compressed tablets using specific coated particles, wherein the coating (system) comprises at least one wax and/or at least one fat. Furthermore it relates to compressed (compacted) tablets and as well as to specific coated particles.

公开(公告)号：US20160030305A1

公开(公告)日：2016-02-04

申请号：US14774855

申请日：2014-03-14

Applicant: DSM IP ASSETS B.V.

Inventor： Jochen WEISS ,  Christiane MAIER ,  Anne KESSLER ,  Concetta TEDESCHI ,  Bruno LEUENBERGER ,  Markus NOVOTNY

IPC: A61K8/06 ,  A23K1/00 ,  A61Q19/00 ,  A23L1/00 ,  A61K8/37 ,  A61K8/55

CPC classification number: A61K8/06 ,  A23K40/30 ,  A23L27/72 ,  A23P10/35 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/37 ,  A61K8/375 ,  A61K8/553 ,  A61K9/10 ,  A61K9/5176 ,  A61K47/14 ,  A61K2800/10 ,  A61K2800/412 ,  A61K2800/652 ,  A61Q19/00

Abstract: The present invention relates to new (foodgrade) solid lipid nanoparticles, as well as the production of such solid lipid nanoparticles and the use of them.

Abstract translation: 本发明涉及新的（食用级）固体脂质纳米颗粒，以及这种固体脂质纳米颗粒的生产及其用途。

公开(公告)号：US20180282579A1

公开(公告)日：2018-10-04

申请号：US15763532

申请日：2016-09-23

Applicant: DSM IP ASSETS B.V.

Inventor： Michael ADAMS ,  Bruno LEUENBERGER ,  Loni SCHWEIKERT ,  Olivia VIDONI ,  Yan ZHANG ,  Zhibing ZHANG

IPC: C09D191/06 ,  A61K9/50 ,  A61K9/20

Abstract: The present patent application relates to a novel coating system, wherein the coating comprises Carnauba wax and at least one polysorbate. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of tablets.

公开(公告)号：US20180280309A1

公开(公告)日：2018-10-04

申请号：US15763525

申请日：2016-09-23

Applicant: DSM IP ASSETS B.V.

Inventor： Jihane ACHKAR ,  Sylvain DIGUET ,  Bruno LEUENBERGER ,  Loni SCHWEIKERT ,  Olivia VIDONI

IPC: A61K9/20 ,  A61K31/07 ,  A61K9/50 ,  A61K31/015 ,  A61K31/047 ,  A61K31/593 ,  A61K31/375 ,  A61K31/355 ,  A61K31/51 ,  A61K31/525 ,  A61K31/455 ,  A61K31/197 ,  A61K31/675 ,  A61K31/4188 ,  A61K31/519 ,  A61K31/714 ,  A61K31/122 ,  A61K33/26 ,  A61K33/34 ,  A61K33/24 ,  A61K33/30 ,  A61K33/18 ,  A61K33/04 ,  A61K33/00 ,  A61K33/06

Abstract: The present patent application relates a process for the production of compressed tablets using specific coated particles, wherein the coating (system) comprises at least one wax and/or at least one fat. Furthermore it relates to compressed (compacted) tablets and as well as to specific coated particles.