公开(公告)号：US12128158B2

公开(公告)日：2024-10-29

申请号：US18108038

申请日：2023-02-10

Applicant: DSM IP Assets B.V.

Inventor： Noel L. Davison ,  Henricus Johannes Arts ,  Aylvin Jorge Angelo Athanasius Dias ,  Anne Marie Persson ,  Ruud Jozef Regina Wilhelmus Peters

IPC: A61L31/08 ,  A61L17/04 ,  A61L17/14 ,  A61L27/18 ,  A61L27/32 ,  A61L27/34 ,  A61L31/06 ,  A61L31/10 ,  C08L75/04

CPC classification number: A61L31/086 ,  A61L17/04 ,  A61L17/145 ,  A61L27/18 ,  A61L27/32 ,  A61L27/34 ,  A61L31/06 ,  A61L31/10 ,  C08L75/04 ,  A61L2420/02 ,  A61L2430/02 ,  A61L2430/38

Abstract: The disclosure relates to a method of making a bioceramic coating on a fibrous article for use in a medical implant, comprising steps of providing an article comprising fibers made from a biocompatible, non-biodegradable polymer; coating at least the fibers that will be in contact with bone upon use as an implant with a solution of a coating polymer to result in coated fibers having a coating polymer layer; treating the coated fibers with a dispersion of bioactive ceramic particles 0.01-10 μm in a treating solvent comprising a solvent for the coating polymer in at least one step; and substantially removing the treating solvent; to result in the particles being partly embedded in the coating polymer layer of the coated fibers.

公开(公告)号：US12016977B2

公开(公告)日：2024-06-25

申请号：US16753355

申请日：2018-10-05

Applicant: DSM IP Assets B.V.

Inventor： Noel L. Davison ,  Henricus Johannes Arts ,  Aylvin Jorge Angelo Athanasius Dias ,  Anne Marie Persson ,  Ruud Jozef Regina Wilhelmus Peters

IPC: A61L31/08 ,  A61L17/04 ,  A61L17/14 ,  A61L27/18 ,  A61L27/32 ,  A61L27/34 ,  A61L31/06 ,  A61L31/10 ,  C08L75/04

CPC classification number: A61L31/086 ,  A61L17/04 ,  A61L17/145 ,  A61L27/18 ,  A61L27/32 ,  A61L27/34 ,  A61L31/06 ,  A61L31/10 ,  C08L75/04 ,  A61L2420/02 ,  A61L2430/02 ,  A61L2430/38

Abstract: The disclosure relates to a method of making a bioceramic coating on a fibrous article for use in a medical implant, comprising steps of providing an article comprising fibers made from a biocompatible, non-biodegradable polymer; coating at least the fibers that will be in contact with bone upon use as an implant with a solution of a coating polymer to result in coated fibers having a coating polymer layer; treating the coated fibers with a dispersion of bioactive ceramic particles 0.01-10 μm in a treating solvent comprising a solvent for the coating polymer in at least one step; and substantially removing the treating solvent; to result in the particles being partly embedded in the coating polymer layer of the coated fibers.