公开(公告)号：US20220064155A1

公开(公告)日：2022-03-03

申请号：US17269325

申请日：2019-08-27

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Wol Young Kim ,  Yeon Im Lee ,  Youn Jung Yoon ,  Joon Seok Park ,  Deok Ki Eom ,  Keuk-Chan Bang ,  Jaehyun Jung

IPC分类号： C07D417/14 ,  C07D471/04 ,  C07D413/04

摘要： The present disclosure relates to a novel heterocyclic amine derivative represented by the following Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers. wherein, in Chemical Formula 1, R1, R2, X1, X2, L, Y, A and B are the same as defined in the specification.

公开(公告)号：US20200223821A1

公开(公告)日：2020-07-16

申请号：US16650441

申请日：2018-10-11

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Wol-Young Kim ,  Jung-eun Park ,  Keuk-Chan Bang ,  Joon-Seok Park

IPC分类号： C07D401/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D401/14

摘要： The present disclosure relates to a novel phenylpyridine derivative represented by Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers.

公开(公告)号：US11180496B2

公开(公告)日：2021-11-23

申请号：US16629392

申请日：2018-07-12

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Keuk-Chan Bang ,  Deok Ki Eom ,  Joon Seok Park

IPC分类号： C07D471/04

摘要： The present invention relates to a novel 1H-pyrazolopyridine derivative and a pharmaceutical composition containing the same. The 1H-pyrazolopyridine derivative and the pharmaceutical composition containing the same can be usefully used for the prevention or treatment of autoimmune diseases or cancer.

公开(公告)号：US11149019B2

公开(公告)日：2021-10-19

申请号：US16650441

申请日：2018-10-11

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Wol-Young Kim ,  Jung-eun Park ,  Keuk-Chan Bang ,  Joon-Seok Park

IPC分类号： C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

摘要： The present disclosure relates to a novel phenylpyridine derivative represented by Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers.

公开(公告)号：US10399988B2

公开(公告)日：2019-09-03

申请号：US16097646

申请日：2017-07-07

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Youn-Jung Yoon ,  Jung-Eun Park ,  Yeon-Jung Park ,  Min-June Shim ,  Keuk-Chan Bang ,  Joon-Seok Park

IPC分类号： C07D487/04 ,  A61K31/519 ,  C07D519/00 ,  A61P35/00

摘要： The present invention relates to 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same, wherein the 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing them not only have BTK inhibitory activity but also has remarkably high selectivity for the inhibitory activity of BTK vs. ITK, and thereby can be usefully used for the prevention or treatment of autoimmune diseases or cancers as BTK inhibitors.