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公开(公告)号:US20140369942A1
公开(公告)日:2014-12-18
申请号:US14370327
申请日:2013-01-04
发明人: Sang-Ho Lee , Jun-Hee Lee , Hyo-Shin Kim , Yeon-Jung Park
CPC分类号: A61K8/63 , A61K9/0053 , A61K31/575 , A61K36/899 , A61K36/9066 , A61K2800/782 , A61Q11/00 , A61K2300/00
摘要: Provided is a method for preventing or treating a periodontal disease; or a method for improving oral hygiene, including administering a pharmaceutical composition containing tauroursodeoxycholic acid as an active ingredient.
摘要翻译: 提供了预防或治疗牙周病的方法; 或改善口腔卫生的方法,包括施用含有葡萄糖脱氧胆酸的药物组合物作为活性成分。
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公开(公告)号:US10399988B2
公开(公告)日:2019-09-03
申请号:US16097646
申请日:2017-07-07
发明人: Youn-Jung Yoon , Jung-Eun Park , Yeon-Jung Park , Min-June Shim , Keuk-Chan Bang , Joon-Seok Park
IPC分类号: C07D487/04 , A61K31/519 , C07D519/00 , A61P35/00
摘要: The present invention relates to 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same, wherein the 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing them not only have BTK inhibitory activity but also has remarkably high selectivity for the inhibitory activity of BTK vs. ITK, and thereby can be usefully used for the prevention or treatment of autoimmune diseases or cancers as BTK inhibitors.
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公开(公告)号:US09301911B2
公开(公告)日:2016-04-05
申请号:US14370327
申请日:2013-01-04
发明人: Sang-Ho Lee , Jun-Hee Lee , Hyo-Shin Kim , Yeon-Jung Park
IPC分类号: A61Q11/00 , A61K45/06 , A61K8/19 , A61K8/97 , A61K8/63 , A61K31/575 , A61K9/00 , A61K36/899 , A61K36/9066
CPC分类号: A61K8/63 , A61K9/0053 , A61K31/575 , A61K36/899 , A61K36/9066 , A61K2800/782 , A61Q11/00 , A61K2300/00
摘要: Provided is a method for preventing or treating a periodontal disease; or a method for improving oral hygiene, including administering a pharmaceutical composition containing tauroursodeoxycholic acid as an active ingredient.
摘要翻译: 提供了预防或治疗牙周病的方法; 或改善口腔卫生的方法,包括施用含有葡萄糖脱氧胆酸的药物组合物作为活性成分。
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