公开(公告)号：US06506784B1

公开(公告)日：2003-01-14

申请号：US09606986

申请日：2000-06-29

申请人： Daljit S. Dhanoa ,  Dario Doller ,  Sanath Meegalla ,  Richard M. Soll ,  Dimitris Agrafiotis ,  Nancy Wisnewski ,  Gary M. Silver ,  Dan T. Stinchcomb ,  R. Lee Seward

发明人： Daljit S. Dhanoa ,  Dario Doller ,  Sanath Meegalla ,  Richard M. Soll ,  Dimitris Agrafiotis ,  Nancy Wisnewski ,  Gary M. Silver ,  Dan T. Stinchcomb ,  R. Lee Seward

IPC分类号： A01N4356

CPC分类号： A01N43/56

摘要： The present invention is directed to inhibiting pest GABA receptors by contacting said receptors with a compound of Formula I: The invention is also directed to methods of controlling pests, especially insects and arachnids such as fleas and ticks, and to novel compounds within the scope of Formula I.

摘要翻译： 本发明涉及通过使所述受体与式I化合物接触来抑制病虫害GABA受体：本发明还涉及防治害虫，特别是昆虫和蜘蛛如跳蚤和蜱的方法，以及在本发明范围内的新化合物 一级方程式

公开(公告)号：US06518266B1

公开(公告)日：2003-02-11

申请号：US09621456

申请日：2000-07-21

申请人： Daljit S. Dhanoa ,  Dario Doller ,  Sanath Meegalla ,  Richard M. Soll ,  Nancy Wisnewski ,  Gary Silver ,  Dan T. Stinchcomb ,  R. Lee Seward ,  Dimitris Agrafiotis ,  Deyou Sha

发明人： Daljit S. Dhanoa ,  Dario Doller ,  Sanath Meegalla ,  Richard M. Soll ,  Nancy Wisnewski ,  Gary Silver ,  Dan T. Stinchcomb ,  R. Lee Seward ,  Dimitris Agrafiotis ,  Deyou Sha

IPC分类号： C07D23124

CPC分类号： C07D403/04 ,  A01N43/56 ,  A01N43/82 ,  A01N55/00 ,  C07D231/18 ,  C07D231/20 ,  C07D231/44 ,  C07D231/52 ,  C07D409/04 ,  C07D413/04

摘要： The present invention is directed to novel pyrazole derivatives and their use as pesticidal agents. The pyrazole derivatives have Formula I: or a salt thereof, where R1 represents R5O, R5SO2, R5SO or R5S in which R5 is as defined herein; X is halo, cyano, C1-6 alkoxycarbonyl, C2-6 alkynyl, optionally substituted C6-14 aryl or an optionally substituted 5- to 7-membered heteroaromatic ring linked to thiazole via a carbon-carbon bond; R2 is hydrogen, amino, chloro, bromo, iodo, cyano, C1-6 alkoxy, C1-6 alkyl or C6-10 aryl; and R3-R7 each represent hydrogen, halogen, straight- or branched-chain C1-4 alkyl or C1-4 alkoxy, either of which is unsubstituted or substituted by one or more halogen atoms, straight- or branched-chain C1-4 alkylthio or C1-4 alkylsulphinyl, either of which is substituted by one or more halogen atoms, nitro, cyano, or straight- or branched-chain C1-4 alkylsulphonyl group which is unsubstituted or substituted by one or more halogen atoms.

摘要翻译： 本发明涉及新颖的吡唑衍生物及其作为杀虫剂的用途。 吡唑衍生物具有式I或其盐，其中R 1表示其中R 5如本文所定义的R5O，R5SO2，R5SO或R5S; X为卤素，氰基，C1-6烷氧基羰基，C2-6炔基，任选取代的C6-14 芳基或通过碳 - 碳键与噻唑连接的任选取代的5至7元杂芳环; R 2是氢，氨基，氯，溴，碘，氰基，C 1-6烷氧基，C 1-6烷基或C 6-10 芳基; 和R 3 -R 7各自表示氢，卤素，直链或支链C 1-4烷基或C 1-4烷氧基，其中任一个是未取代的或被一个或多个卤素原子，直链或支链C 1-4烷硫基或 任选被一个或多个卤素原子取代的C 1-4烷基亚磺酰基，未被取代或被一个或多个卤素原子取代的硝基，氰基或直链或支链C 1-4烷基磺酰基。

公开(公告)号：US5837228A

公开(公告)日：1998-11-17

申请号：US939539

申请日：1992-09-02

申请人： Chung Shih ,  Gaylen M. Zentner ,  Randall V. Sparer ,  R. Lee Seward

发明人： Chung Shih ,  Gaylen M. Zentner ,  Randall V. Sparer ,  R. Lee Seward

IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K9/58 ,  A61K31/35 ,  A61K31/365 ,  A61K31/74 ,  A61K47/48 ,  A61P33/00 ,  A61P33/10 ,  A61K9/14 ,  A61F2/02

CPC分类号： A61K9/0024 ,  A61K47/48192 ,  A61K47/482 ,  A61K9/204 ,  Y10S514/953

摘要： A bioerodible controlled release dosage form is disclosed comprising a polymer formed by condensing beneficial agents having a hydroxyl functionality of two or more with diketene acetals or divinyl ethers which delivers beneficial agents to a biological environment of use. A statistically significant portion of the beneficial agent is covalently bonded within the polymer matrix.

摘要翻译： 公开了一种生物腐蚀性控制释放剂型，其包含通过将具有两个或更多个羟基官能团的有益剂与双烯酮缩醛或二乙烯基醚缩合形成的聚合物，其将有益剂递送到生物生物学环境。 有益试剂的统计学显着部分共价键合在聚合物基质内。