公开(公告)号：US06721591B2

公开(公告)日：2004-04-13

申请号：US09910837

申请日：2001-07-24

申请人： Daming Wei ,  Takeshi Kojima ,  Tadashi Nakayama ,  Yoshio Sakai

发明人： Daming Wei ,  Takeshi Kojima ,  Tadashi Nakayama ,  Yoshio Sakai

IPC分类号： A61B50402

CPC分类号： A61B5/0006 ,  A61B5/04028 ,  A61B5/0404 ,  A61B5/0432

摘要： A plurality of electrodes for measuring electrocardiogarphic waveforms are attached on body surface positions that constitute a subset of the standard 12-lead system. The measured electrocardiogarphic waveforms of said subset of said standard 12-lead system are used to calculate the electrocardiogarphic waveforms of remaining leads in the said standard 12-lead system. The measured and calculated electrocardiographic waveforms are synthesized to form a standard 12-lead electrocardiogram. The invention is capable of monitoring the 12-lead electrocardiogram with a reduced number of electrodes, wherein a portion of waveforms are directly measured and used as primary information for diagnosing heart disease, and the other portion of waveforms are derived from the measured leads and are used as a secondary information for improving the accuracy of diagnosis. The invention is especially useful in monitoring ischemic heart disease and acute myocardial infarction in cases where mounting and maintaining ten electrodes to obtain 12-lead electrocardiogram is difficult, such as in ambulatory monitoring, long-term monitoring and home monitoring.

摘要翻译： 用于测量心电波形波形的多个电极附着在构成标准12引导系统的子集的体表位置上。 所述标准12引导系统的所述子集的测量的心电图波形用于计算所述标准12引导系统中剩余引线的心电图波形。 合成测量和计算的心电图波形，形成标准的12导联心电图。 本发明能够以减少数量的电极监测12导联心电图，其中一部分波形被直接测量并用作用于诊断心脏病的主要信息，波形的另一部分来自测量引线，并且是 用作提高诊断准确度的次要信息。 本发明特别适用于监测缺血性心脏病和急性心肌梗死，如安装和维持十个电极获得12导联心电图难度较大，例如在动态监测，长期监测和家庭监测中。

公开(公告)号：US07613506B2

公开(公告)日：2009-11-03

申请号：US11212565

申请日：2005-08-29

申请人： Daming Wei ,  Yoshio Sakai

发明人： Daming Wei ,  Yoshio Sakai

IPC分类号： A61B5/04

CPC分类号： A61B5/04028 ,  A61B5/0402 ,  A61B5/0428

摘要： Four first electrodes are attached on right clavicle, the vicinity of on left clavicle, on right lowermost rib, and the position on left lowermost rib, corresponding to limb leads 12-lead electrocardiogram (ECG). Two second electrodes are attached on such positions of the living body that correspond to a lead V2 and a lead V4 of 12-lead ECG. First ECG data set correspond to leads I and II of 12-lead ECG. A second ECG data set including the leads V2 and V4. A heart vector is calculated on the first and second ECG data sets, and predetermined first lead vectors of leads I, II, V2 and V4. A third ECG data set including leads V1, V3, V5 and V6 is calculated based on the heart vector and predetermined second lead vectors of leads V1, V3, V5 and V6. A fourth ECG data set from leads III, aVR, aVL and aVF of 12-lead ECG based on the first ECG data set. The 12-lead ECG is derived based on the first to fourth ECG data sets.

摘要翻译： 四个第一电极连接在右锁骨上，左锁骨附近，右下肋骨和左下肋骨上的位置，对应于肢体引线12引导心电图（ECG）。 两个第二电极附接在对应于引线V2和12导联ECG的引线V4的活体的这样的位置上。 第一个ECG数据集对应于12导联心电图的导联I和II。 包括引线V2和V4的第二个ECG数据集。 在第一和第二ECG数据集以及引线I，II，V2和V4的预定的第一引导向量上计算心向量。 基于引线V1，V3，V5和V6的心向量和预定的第二引导向量计算包括引线V1，V3，V5和V6的第三ECG数据集。 基于第一个ECG数据集的来自导联III，aVR，aVL和12导联心电图的aVF的第四个ECG数据集。 12导联ECG是基于第一至第四ECG数据集导出的。

公开(公告)号：US20060047212A1

公开(公告)日：2006-03-02

申请号：US11212565

申请日：2005-08-29

申请人： Daming Wei ,  Yoshio Sakai

发明人： Daming Wei ,  Yoshio Sakai

IPC分类号： A61B5/0402

CPC分类号： A61B5/04028 ,  A61B5/0402 ,  A61B5/0428

摘要： Four first electrodes are attached on the vicinity of a lower right end of a right clavicle, the vicinity of a lower left end of a left clavicle, the vicinity of a position on a right anterior axillary line at the level of a right lowermost rib, a the vicinity of a position on a left anterior axillary line at the level of a left lowermost rib of a living body, so as to correspond to limb leads of a standard 12-lead electrocardiogram (ECG). Two second electrodes are attached on such positions of the living body that correspond to a lead V2 and a lead V4 of chest leads of the standard 12-lead ECG. A first ECG data set corresponding to leads I and II of the standard 12-lead EGG with the first electrodes. A second ECG data set including the leads V2 and V4 with the second electrodes. An instantaneous electromotive force vector (a heart vector) is calculated based on the first and second ECG data sets, and predetermined first lead vectors of the leads I, II, V2 and V4. A third ECG data set including leads V1, V3, V5 and V6 of the chest leads is calculated based on the heart vector-and predetermined second lead vectors of the leads V1, V3, V5 and V6. A fourth EGG data set corresponding to leads III, aVR, aVL and aVF of the standard 12-lead EGG based on the first ECG data set The standard 12-lead EGG is derived based on the first to fourth ECG data sets.

摘要翻译： 四个第一电极附着在右锁骨的右下端附近，左锁骨左下端附近，右下腋下线位于右下肋骨附近， 在生物体的左下肋骨的水平处的左前腋细线上的位置附近，以与标准12导联心电图（ECG）的肢体引线相对应。 两个第二电极附接在对应于标准12导联ECG的胸部引线的引线V 2和引线V 4的生物体的这些位置上。 对应于具有第一电极的标准12导联EGG的引线I和II的第一ECG数据集。 包括具有第二电极的引线V 2和V 4的第二ECG数据集。 基于第一和第二ECG数据集以及引线I，II，V 2和V 4的预定的第一引导向量来计算瞬时电动势矢量（心脏矢量）。 基于引线V 1，V 3，V 5和V 6的心脏矢量和预定的第二引导矢量计算包括胸部引线的引线V 1，V 3，V 5和V 6的第三ECG数据集。 基于第一ECG数据集的与标准12导联EGG的引线III，aVR，aVL和aVF相对应的第四个EGG数据集。基于第一至第四ECG数据集导出标准的12引导EGG。

公开(公告)号：US07647094B2

公开(公告)日：2010-01-12

申请号：US11129421

申请日：2005-05-16

申请人： Daming Wei

发明人： Daming Wei

IPC分类号： A61B5/04

CPC分类号： A61B5/04028 ,  A61B5/0402 ,  A61B5/0452

摘要： In order to derive a standard 12-lead electrocardiogram, ones of limb leads and chest leads which constitute a lead system for the standard 12-lead electrocardiogram using 10 electrodes are selected. Electrocardiographic waveforms corresponding to the selected ones of the limb leads and the chest leads are obtained, as measured electrocardiographic waveforms, with electrodes attached on a living body. Electrocardiographic waveforms corresponding to a remaining ones of the limb leads and the chest leads are calculated, as non-measured electrocardiographic waveforms, with a prescribed transformation matrix and the measured electrocardiographic waveforms.

摘要翻译： 为了获得标准的12导联心电图，选择构成使用10个电极的标准12导联心电图的引导系统的肢体引线和胸导线。 作为测量的心电波形，获得与选定的肢体引线和胸部引线相对应的心电图波形，其中电极附着在活体上。 使用规定的变换矩阵和测量的心电图波形计算与剩余的肢体引线和胸部引线相对应的心电图波形作为未测量的心电波形。

公开(公告)号：US08843193B2

公开(公告)日：2014-09-23

申请号：US13784894

申请日：2013-03-05

申请人： Daming Wei ,  Nihon Kohden Corporation

发明人： Daming Wei ,  Jiro Suto ,  Takashi Kaiami ,  Motoki Sakai

IPC分类号： A61B5/04 ,  A61B5/0452 ,  A61B5/0402

CPC分类号： A61B5/0452 ,  A61B5/04011 ,  A61B5/04012 ,  A61B5/04028

摘要： A TWA measuring apparatus includes: an electrocardiograph controlling section which is configured to produce an electrocardiogram from electrocardiographic signals of a subject; and a TWA measuring section which is configured to select at least two waveforms that contribute to a measurement of TWA, from the electrocardiogram, and which is configured to measure a presence of TWA by using the selected at least two waveforms.

摘要翻译： TWA测量装置包括：心电图仪控制部分，被配置为从对象的心电图信号产生心电图; 以及TWA测量部分，被配置为从所述心电图中选择有助于测量TWA的至少两个波形，并且被配置为通过使用所选择的至少两个波形来测量TWA的存在。

公开(公告)号：US20060235317A1

公开(公告)日：2006-10-19

申请号：US10546785

申请日：2004-02-26

申请人： Daming Wei

发明人： Daming Wei

IPC分类号： A61B5/0402

CPC分类号： A61B5/0402

摘要： There are provided an electrocardiograph with an extended lead function and an extended lead ECG deriving method capable of easily deriving an ECG signal of an extended lead ECG by an arithmetic operation, based on ECG signals of a standard 12-lead ECG measured by a potential detector 10. An ECG memory 12 stores the ECG signals measured as the standard 12-lead ECG by the potential detector 10. An extended lead ECG calculator 16 calculates extended lead ECGs V7-V9 from the ECG signals stored in the ECG memory 12, using coefficients α representing a relationship among leads. The extended lead ECGs V7-V9 calculated are displayed through an extended lead ECG waveform outputting device 18 on a display monitor 20.

摘要翻译： 提供了具有延长引线功能的心电图仪和可扩展导联ECG导出方法，该方法能够通过算术运算轻松导出扩展导联ECG的ECG信号，基于由潜在检测器测量的标准12导联ECG的ECG信号 10。 ECG存储器12存储由潜在检测器10测量为标准12导联ECG的ECG信号。 延长引线ECG计算器16使用存储在ECG存储器12中的ECG信号，使用表示引线之间的关系的系数α来计算延长引导ECG V 7 -V 9。 计算出的延长导联ECG V 7 -V 9通过显示监视器20上的延长引导ECG波形输出装置18显示。

公开(公告)号：US20060025695A1

公开(公告)日：2006-02-02

申请号：US11129421

申请日：2005-05-16

申请人： Daming Wei

发明人： Daming Wei

IPC分类号： A61B5/04 ,  A61B5/0402

CPC分类号： A61B5/04028 ,  A61B5/0402 ,  A61B5/0452

摘要： In order to derive a standard 12-lead electrocardiogram, ones of limb leads and chest leads which constitute a lead system for the standard 12-lead electrocardiogram using 10 electrodes are selected. Electrocardiographic waveforms corresponding to the selected ones of the limb leads and the chest leads are obtained, as measured electrocardiographic waveforms, with electrodes attached on a living body. Electrocardiographic waveforms corresponding to a remaining ones of the limb leads and the chest leads are calculated, as non-measured electrocardiographic waveforms, with a prescribed transformation matrix and the measured electrocardiographic waveforms.

摘要翻译： 为了获得标准的12导联心电图，选择构成使用10个电极的标准12导联心电图的引导系统的肢体引线和胸导线。 作为测量的心电波形，获得与选定的肢体引线和胸部引线相对应的心电图波形，其中电极附着在活体上。 使用规定的变换矩阵和测量的心电图波形计算与剩余的肢体引线和胸部引线相对应的心电图波形作为未测量的心电波形。

公开(公告)号：US08335560B2

公开(公告)日：2012-12-18

申请号：US13194014

申请日：2011-07-29

申请人： Daming Wei

发明人： Daming Wei

IPC分类号： A61B5/04

CPC分类号： A61B5/04028 ,  A61B5/0006 ,  G16H10/60

摘要： A derived electrocardiogram generating system includes: a personal coefficient database which stores personal coefficients specific to a subject, the personal coefficients being acquired from the subject; a population coefficient database which stores population coefficients which are average values of conversion coefficients acquired from an unspecified large number of persons belonging to a statistically significant population; and an electrocardiograph control portion: which generates a derived electrocardiogram of the subject using the personal coefficients when the personal coefficients are present in the personal coefficient database; and which generates a derived electrocardiogram of the subject using the population coefficients when the personal coefficients are absent in the personal coefficient database.

摘要翻译： 导出的心电图生成系统包括：个人系数数据库，其存储对对象特有的个人系数，从被检体取得的个人系数; 一种人口系数数据库，其存储从未指定的大量属于统计学上显着的群体的人获得的转化系数的平均值的人口系数; 以及心电图控制部分：当所述个人系数存在于所述个人系数数据库中时，使用所述个人系数生成所述被检体的导出心电图; 并且当个人系数数据库中的个人系数不存在时，其使用群体系数来生成受试者的导出心电图。

公开(公告)号：US5521851A

公开(公告)日：1996-05-28

申请号：US233684

申请日：1994-04-26

申请人： Daming Wei ,  Eishi Harasawa ,  Hajime Harada

发明人： Daming Wei ,  Eishi Harasawa ,  Hajime Harada

IPC分类号： H04B1/12 ,  H04B15/00

CPC分类号： H04B1/123

摘要： A method and apparatus is disclosed to reduce noise which overlaps detected signals in a common frequency band for detection of distributed signals from multiple measurement points. The method decomposes a input signal into a noise-free part called basic signal and a noise-overlapping part called residual signal. Noise contained in residual signal is recognized by comparing it with a comparison signal. The comparison signal corresponding to a measurement point is computed by a linear combination of all other points weighted with parameters which reflect amplitude relationship of distributed signals and are calculated during a learning phase at the beginning of measurement. With residual signal and corresponding comparison signal, a noise index is calculated and then used to extract signal components from the residual signal. The extracted signal components are added to basic signal as the output of the method. The method is effective in reducing signal-overlapping noise with little distortion of signal.

摘要翻译： 公开了一种减少噪声的方法和装置，其用于检测来自多个测量点的分布式信号的公共频带中的检测信号。 该方法将输入信号分解为称为基本信号的无噪声部分和称为残余信号的噪声重叠部分。 残留信号中包含的噪声通过与比较信号进行比较来识别。 对应于测量点的比较信号通过所有其他点的线性组合计算，所有其他点被加权的参数反射分布信号的幅度关系，并在测量开始时的学习阶段计算。 利用残差信号和对应的比较信号，计算噪声指数，然后用于从残差信号中提取信号分量。 提取的信号分量作为方法的输出被添加到基本信号。 该方法有效减少信号重叠噪声，信号失真小。

公开(公告)号：US09265437B2

公开(公告)日：2016-02-23

申请号：US13434008

申请日：2012-03-29

申请人： Daming Wei ,  Jiro Suto ,  Takashi Kaiami

发明人： Daming Wei ,  Jiro Suto ,  Takashi Kaiami

IPC分类号： A61B5/0402 ,  A61B5/0452 ,  A61B5/04 ,  A61B5/00

CPC分类号： A61B5/0452 ,  A61B5/04011 ,  A61B5/04028 ,  A61B5/7257

摘要： A TWA measuring electrocardiograph includes: a transformation coefficient storing section configured to store a transformation coefficient for deriving a Frank's vector electrocardiogram; an electrocardiograph controlling section configured to produce a scalar electrocardiogram from electrocardiographic signals of measurement electrodes adapted to be attached to a subject, and configured to derive the Frank's vector electrocardiogram from the scalar electrocardiogram by using the transformation coefficient; and a TWA measuring section configured to measure a presence of TWA based on the derived Frank's vector electrocardiogram.

摘要翻译： TWA测量心电图仪包括：变换系数存储部分，被配置为存储用于导出弗兰克矢量心电图的变换系数; 心电图控制部，被配置为通过适于附着于被检体的测定电极的心电图信号产生标量心电图，并且被配置为通过使用所述变换系数从所述标量心电图导出所述弗兰克氏矢量心电图; TWA测量部分被配置为基于导出的弗兰克向量心电图测量TWA的存在。