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    Hemodynamic status assessment during tachycardia
    1.
    发明申请
    Hemodynamic status assessment during tachycardia 有权
    心动过速时的血液动力学状态评估

    公开(公告)号：US20090131999A1

    公开(公告)日：2009-05-21

    申请号：US12283234

    申请日：2008-09-10

    申请人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    发明人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36585 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578

    摘要： Systems and methods provide for sensing, during an event of tachycardia, hemodynamic signals concurrently from at least two spatially separated locations within a patient, and quantifying a spatial relationship between the hemodynamic signals. Hemodynamic stability or state of the patient during the tachycardia event is determine based at least in part on the quantified spatial relationship. One or more anti-tachycardia therapies to treat the tachycardia may be selected based at least in part on the determined stability or state of patient hemodynamics, and the selected one or more anti-tachycardia therapies may be delivered to treat the tachycardia. The hemodynamic signals may comprise at least two, or a mixed combination, of cardiac impedance signals, cardiac chamber pressure signals, arterial pressure signals, heart sounds; and acceleration signals.

    摘要翻译： 系统和方法提供在心动过速事件期间从患者内的至少两个空间上分离的位置同时感测血液动力学信号，并且量化血液动力学信号之间的空间关系。 至少部分地基于定量的空间关系确定在心动过速事件期间患者的血流动力学稳定性或状态。 可以至少部分地基于所确定的患者血液动力学的稳定性或状态来选择治疗心动过速的一种或多种抗心动过速疗法，并且可以递送所选择的一种或多种抗心动过速疗法以治疗心动过速。 血液动力学信号可以包括心脏阻抗信号，心室压力信号，动脉压信号，心音的至少两个或混合组合; 和加速度信号。

    Hemodynamic status assessment during tachycardia
    2.
    发明授权
    Hemodynamic status assessment during tachycardia 有权
    心动过速时的血液动力学状态评估

    公开(公告)号：US08838240B2

    公开(公告)日：2014-09-16

    申请号：US12283234

    申请日：2008-09-10

    申请人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    发明人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    IPC分类号： A61N1/36 ,  A61N1/368 ,  A61B5/0464 ,  A61N1/365

    CPC分类号： A61N1/36585 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578

    摘要： Systems and methods provide for sensing, during an event of tachycardia, hemodynamic signals concurrently from at least two spatially separated locations within a patient, and quantifying a spatial relationship between the hemodynamic signals. Hemodynamic stability or state of the patient during the tachycardia event is determined based at least in part on the quantified spatial relationship. One or more anti-tachycardia therapies to treat the tachycardia may be selected based at least in part on the determined stability or state of patient hemodynamics, and the selected one or more anti-tachycardia therapies may be delivered to treat the tachycardia. The hemodynamic signals may comprise at least two, or a mixed combination, of cardiac impedance signals, cardiac chamber pressure signals, arterial pressure signals, heart sounds; and acceleration signals.

    摘要翻译： 系统和方法提供在心动过速事件期间从患者内的至少两个空间上分离的位置同时感测血液动力学信号，并且量化血液动力学信号之间的空间关系。 至少部分地基于定量的空间关系确定在心动过速事件期间患者的血流动力学稳定性或状态。 可以至少部分地基于所确定的患者血液动力学的稳定性或状态来选择治疗心动过速的一种或多种抗心动过速疗法，并且可以递送所选择的一种或多种抗心动过速疗法以治疗心动过速。 血液动力学信号可以包括心脏阻抗信号，心室压力信号，动脉压信号，心音的至少两个或混合组合; 和加速度信号。

    METHOD AND APPARATUS FOR DETECTING ATRIAL FILLING PRESSURE
    6.
    发明申请
    METHOD AND APPARATUS FOR DETECTING ATRIAL FILLING PRESSURE 有权
    用于检测心律灌注压的方法和装置

    公开(公告)号：US20070066913A1

    公开(公告)日：2007-03-22

    申请号：US11558967

    申请日：2006-11-13

    申请人： Abhilash Patangay ,  Krzysztof Siejko

    发明人： Abhilash Patangay ,  Krzysztof Siejko

    IPC分类号： A61B5/02

    CPC分类号： A61B5/02028 ,  A61B7/00 ,  A61N1/36514 ,  A61N1/36528

    摘要： A cardiac rhythm management system provides for ambulatory monitoring of hemodynamic performance based on quantitative measurements of heart sound related parameters for diagnostic and therapeutic purposes. Monitoring of such heart sound related parameters allows the cardiac rhythm management system to determine a need for delivering a therapy and/or therapy parameter adjustments based on conditions of a heart. This monitoring also allows a physician to observe or assess the hemodynamic performance for diagnosing and making therapeutic decisions. Because the conditions of the heart may fluctuate and may deteriorate significantly between physician visits, the ambulatory monitoring, performed on a continuous or periodic basis, ensures a prompt response by the cardiac rhythm management system that may save a life, prevent hospitalization, or prevent further deterioration of the heart.

    摘要翻译： 心律管理系统基于用于诊断和治疗目的的心音相关参数的定量测量，提供对血液动力学性能的动态监测。 监测这种心脏声音相关参数允许心律管理系统基于心脏的情况来确定递送治疗和/或治疗参数调整的需要。 该监测还允许医师观察或评估用于诊断和作出治疗决定的血液动力学性能。 由于心脏的状况可能波动，并且可能在医师访问之间显着恶化，所以在连续或周期性的基础上进行的动态监测可确保心律管理系统能够节省生命，预防住院或进一步防止心律失常的迅速反应 心脏恶化

    Systems and methods for valvular regurgitation detection
    7.
    发明申请
    Systems and methods for valvular regurgitation detection 有权
    瓣膜反流检测系统及方法

    公开(公告)号：US20070123943A1

    公开(公告)日：2007-05-31

    申请号：US11287978

    申请日：2005-11-28

    申请人： Abhilash Patangay ,  Krzysztof Siejko

    发明人： Abhilash Patangay ,  Krzysztof Siejko

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3627 ,  A61N1/36578

    摘要： A system comprising an implantable medical device (IMD). The IMD includes an implantable sensor operable to produce an electrical signal representative of mechanical activity of a heart of a subject and a controller circuit coupled to the sensor. The controller circuit includes a wavelet filter module and a valvular regurgitation (VR) calculation module. The wavelet filter module is configured to extract signal energy information from the electrical signal. The energy information includes variation of signal amplitude with frequency and time. The VR calculation module is configured to calculate a measurement of VR for one or more heartbeats using the energy information.

    摘要翻译： 一种包括可植入医疗装置（IMD）的系统。 IMD包括可植入传感器，其可操作以产生代表受试者心脏的机械活动的电信号和耦合到传感器的控制器电路。 控制器电路包括小波滤波器模块和瓣膜反流（VR）计算模块。 小波滤波器模块被配置为从电信号中提取信号能量信息。 能量信息包括信号幅度随频率和时间的变化。 VR计算模块被配置为使用能量信息来计算针对一个或多个心跳的VR的测量。

    WIDE QRS DETECTOR
    9.
    发明申请
    WIDE QRS DETECTOR 有权
    宽QRS检测器

    公开(公告)号：US20120310101A1

    公开(公告)日：2012-12-06

    申请号：US13472563

    申请日：2012-05-16

    申请人： Abhilash Patangay ,  Shibaji Shome ,  Pramodsingh Hirasingh Thakur ,  Dan Li ,  Stevens L. Martin

    发明人： Abhilash Patangay ,  Shibaji Shome ,  Pramodsingh Hirasingh Thakur ,  Dan Li ,  Stevens L. Martin

    IPC分类号： A61B5/0472

    CPC分类号： A61B5/0472 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/7239 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/37

    摘要： A system comprises a cardiac signal sensing circuit and a processor circuit. To detect a QRS duration, the processor circuit determines an isoelectric amplitude value of the cardiac signal segment, identifies a time where the cardiac signal segment amplitude deviates from the first isoelectric amplitude value by a specified threshold deviation value as a Q time, determines an isoelectric value time after the determined maxima and minima times that the cardiac signal segment returns to the same or a different isoelectric amplitude value, identifies a time that follows both the determined maxima and minima times and precedes the isoelectric value time as an S time, wherein the cardiac signal segment amplitude at the identified S time satisfies a specified amplitude change criterion from an isoelectric amplitude value, and determines a time duration of the QRS complex in the cardiac signal segment using the identified Q and S times.

    摘要翻译： 一种系统包括心脏信号感测电路和处理器电路。 为了检测QRS持续时间，处理器电路确定心脏信号片段的等电位振幅值，将心脏信号片段振幅与第一等电位振幅值偏离指定阈值偏差值的时间作为Q时间，确定等电点 确定心脏信号段返回到相同或不同等电位振幅值的确定最大值和最小值之后的值时间，识别在确定的最大值和最小值时间之后的时间，并且在等电点时间之前等于S时间，其中 在所识别的S时刻的心脏信号段振幅满足来自等电位振幅值的规定的振幅变化标准，并且使用所识别的Q和S倍来确定心脏信号段中的QRS复合物的持续时间。