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1.发明授权Streptogramin derivatives, their preparation and compositions containing them 有权链球菌素衍生物，它们的制备和含有它们的组合物公开(公告)号：US07166594B2
公开(公告)日：2007-01-23
申请号：US10310773
申请日：2002-12-06
申请人： Daniel Achard , Eric Bacque , Jean-Claude Barriere , Jean Bouquerel , Pascal Desmazeau , Serge Grisoni , Jean-Pierre Leconte , Yves Ribeill , Baptiste Ronan
发明人： Daniel Achard , Eric Bacque , Jean-Claude Barriere , Jean Bouquerel , Pascal Desmazeau , Serge Grisoni , Jean-Pierre Leconte , Yves Ribeill , Baptiste Ronan
IPC分类号： A61K31/535 , A61K31/655 , A61K31/42
CPC分类号： A61K38/12 , A61K38/15 , C07K5/06182 , A61K38/08 , A61K2300/00
摘要： Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond --- represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist
摘要翻译： A组通式（I）的链霉素衍生物，其中：R 1表示卤素原子或叠氮基或硫氰酸根基团，R 2表示氢原子或甲基或 乙基，R 3表示氢原子，或可以被取代的脂族，脂环族，芳族，芳脂族，杂环或杂环脂族酯的残基，并且键 ---表示单键（立体化学27R）或双键，以及其存在时的盐
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2.发明授权Streptogramin derivatives, their preparation and compositions containing them 有权链球菌素衍生物，它们的制备和含有它们的组合物公开(公告)号：US06569854B1
公开(公告)日：2003-05-27
申请号：US09609717
申请日：2000-06-30
申请人： Daniel Achard , Eric Bacque , Jean-Claude Barriere , Jean Bouquerel , Pascal Desmazeau , Serge Grisoni , Jean-Pierre Leconte , Yves Ribeill , Baptiste Ronan
发明人： Daniel Achard , Eric Bacque , Jean-Claude Barriere , Jean Bouquerel , Pascal Desmazeau , Serge Grisoni , Jean-Pierre Leconte , Yves Ribeill , Baptiste Ronan
IPC分类号： A61K3805
CPC分类号： A61K38/12 , A61K38/15 , C07K5/06182 , A61K38/08 , A61K2300/00
摘要： Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond - - - represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist.
摘要翻译： A组通式（I）的链霉素衍生物，其中：R1表示卤素原子或叠氮基或硫氰酸根基，R2表示氢原子或甲基或乙基，R3表示氢原子，或脂族， 脂环族，芳香族，芳脂族，杂环或杂环脂族酯，并且键 - - 表示单键（立体化学27R）或双键，以及它们存在时的盐。
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3.发明授权Streptogramin derivatives, preparation method and compositions containing same 有权链球菌素衍生物，制备方法和含有它们的组合物公开(公告)号：US06958383B2
公开(公告)日：2005-10-25
申请号：US10161804
申请日：2002-06-05
申请人： Pascal Desmazeau , Gilles Doerflinger , Yves Ribeill , Eric Bacque , Jean-Claude Barriere , Gilles Dutruc-Rosset , Gérard Puchault
发明人： Pascal Desmazeau , Gilles Doerflinger , Yves Ribeill , Eric Bacque , Jean-Claude Barriere , Gilles Dutruc-Rosset , Gérard Puchault
摘要： Group B streptogramin derivatives of general formula (I): wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.
摘要翻译： 通式（I）的B组链霉素衍生物：其中Ra，Rb，Rc，Rd，R 1，R 2和Y如说明书中所定义，包括制备 含有其的方法和组合物。 这样的衍生物特别可用作抗微生物剂，任选地与至少一种A链烷togram啉衍生物组合。
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4.发明授权Streptogramin derivatives, preparation method and compositions containing same 有权链球菌素衍生物，制备方法和含有它们的组合物公开(公告)号：US07019110B2
公开(公告)日：2006-03-28
申请号：US10790260
申请日：2004-03-02
申请人： Pascal Desmazeau , Gilles Doerflinger , Yves Ribeill , Eric Bacque , Jean-Claude Barriere , Gilles Dutruc-Rosset , Gérard Puchault
发明人： Pascal Desmazeau , Gilles Doerflinger , Yves Ribeill , Eric Bacque , Jean-Claude Barriere , Gilles Dutruc-Rosset , Gérard Puchault
IPC分类号： C07K7/50
摘要： Group B streptogramin derivatives of general formula (I) are disclosed: wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing the same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.
摘要翻译： 公开了通式（I）的B组链霉素衍生物：其中R a，R b，R c，R d，R 1，R 2和Y如说明书中所定义， 包括制备方法和含有它们的组合物。 这样的衍生物特别可用作抗微生物剂，任选地与至少一种A链烷togram啉衍生物组合。
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公开(公告)号：US07232799B2
公开(公告)日：2007-06-19
申请号：US11193164
申请日：2005-07-29
IPC分类号： A61K38/08
CPC分类号： A61K31/424
摘要： The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B streptogramin derivative
摘要翻译： 本发明公开并要求药物组合物，其包含式（I）的A组链霉素衍生物及其盐与至少一种天然B组链霉素衍生物
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公开(公告)号：US20050267181A1
公开(公告)日：2005-12-01
申请号：US11193164
申请日：2005-07-29
IPC分类号： A61K31/424
CPC分类号： A61K31/424
摘要： The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B streptogramin derivative.
摘要翻译： 本发明公开并要求包含式（I）的A组链霉素衍生物及其盐与至少一种天然B基链球菌素衍生物组合的药物组合物。
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7.发明授权Streptogramin derivatives, their preparation and compositions which contain them 有权链球菌素衍生物，它们的制备和含有它们的组合物公开(公告)号：US06596717B2
公开(公告)日：2003-07-22
申请号：US10024186
申请日：2001-12-21
IPC分类号： A61K3805
CPC分类号： C07D498/18
摘要： Group A streptogramin derivatives of formula (I) and salts thereof: and Group A streptogramin derivatives of formula (III) and salts thereof: as well as processes for preparing such streptogramins, and pharmaceutical compositions comprising such streptogramins, alone or combined with at least one group B streptogramin derivative.
摘要翻译： 式（I）的A组链霉素衍生物及其盐：和式（III）的A组链霉素衍生物及其盐：以及制备此类链霉素的方法，以及包含这样的链霉素的药物组合物，单独或与至少一种 B组链霉素衍生物。
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8.发明授权Streptogramines, their preparation and compositions containing them 失效Streptogramines，它们的制备和含有它们的组合物公开(公告)号：US06815437B1
公开(公告)日：2004-11-09
申请号：US09492392
申请日：2000-01-27
申请人： Alain Commerçon , Hervé Bouchard , Yves Ribeill , Eric Bacque , Baptiste Ronan , Jean-Claude Barriere , Gérard Puchault , Corinne Terrier
发明人： Alain Commerçon , Hervé Bouchard , Yves Ribeill , Eric Bacque , Baptiste Ronan , Jean-Claude Barriere , Gérard Puchault , Corinne Terrier
IPC分类号： A61K3133
CPC分类号： C07K5/06182 , A61K38/00
摘要： Group A streptogramin derivatives of formula (I): the salts thereof, and mixtures of stereoisomers thereof, as well as processes for preparing them and pharmaceutical compositions comprising them are disclosed.
摘要翻译： 公开了式（I）的A组链霉素衍生物：其盐，其立体异构体的混合物，以及其制备方法和包含它们的药物组合物。
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9.发明授权Streptogramin derivatives, their preparation and compositions which contain them 失效链球菌素衍生物，它们的制备和含有它们的组合物公开(公告)号：US06699897B2
公开(公告)日：2004-03-02
申请号：US10400654
申请日：2003-03-28
IPC分类号： A61K3142
CPC分类号： C07D498/18 , A61K38/00 , C07K5/06139
摘要： Group A streptogramin derivatives of formula (I) and salts thereof: Group A streptogramin derivatives of formula (II) and salts thereof: and Group A streptogramin derivatives of formula (III) and salts thereof: as well as processes for preparing such streptogramins, and pharmaceutical compositions comprising such streptogramins, alone or combined with at least one group B streptogramin derivative.
摘要翻译： 式（I）的A组链霉素衍生物及其盐：式（II）的A组链霉素衍生物及其盐：和式（III）的A组链霉素衍生物及其盐：以及制备这些链霉素的方法，以及 包含这样的链霉素的药物组合物，单独或与至少一种B组链霉素衍生物组合。
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10.发明授权Streptogramin derivatives, their preparation and compositions which contain them 失效链球菌素衍生物，它们的制备和含有它们的组合物公开(公告)号：US06562852B2
公开(公告)日：2003-05-13
申请号：US10024698
申请日：2001-12-21
IPC分类号： C07D49822
CPC分类号： C07D498/18 , A61K38/00 , C07K5/06139
摘要： Group A streptogramin derivatives of formula (I) and salts thereof: Group A streptogramin derivatives of formula (II) and salts thereof: and Group A streptogramin derivatives of formula (III) and salts thereof: as well as processes for preparing such streptogramins, and pharmaceutical compositions comprising such streptogramins, alone or combined with at least one group B streptogramin derivative.
摘要翻译： 式（I）的A组链霉素衍生物及其盐：式（II）的A组链霉素衍生物及其盐：和式（III）的A组链霉素衍生物及其盐：以及制备这些链霉素的方法，以及 包含这样的链霉素的药物组合物，单独或与至少一种B组链霉素衍生物组合。
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