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    Method of implanting accommodating intraocular lenses
    1.
    发明申请
    Method of implanting accommodating intraocular lenses 审中-公开
    植入容纳眼内透镜的方法

    公开(公告)号：US20050251254A1

    公开(公告)日：2005-11-10

    申请号：US11180753

    申请日：2005-07-11

    申请人： Daniel Brady ,  Arlene Gwon ,  Thomas Terwee ,  Hendrik Weeber ,  Patricia Piers

    发明人： Daniel Brady ,  Arlene Gwon ,  Thomas Terwee ,  Hendrik Weeber ,  Patricia Piers

    IPC分类号： A61F2/16 ,  A61F9/007 ,  A61F9/013

    CPC分类号： A61F9/00 ,  A61F2/16 ,  A61F2/1613 ,  A61F2/1624 ,  A61F2/1635 ,  A61F9/0017 ,  A61F9/007

    摘要： A method for implanting an intraocular lens into the eye of a subject includes placing the intraocular lens into the eye of a subject and administering a drug in an amount sufficient to maintain an accommodative state of the eye. The method further includes permitting at least a portion of the intraocular lens to become coupled to at least a portion of the eye while maintaining the eye in the accommodative state. In certain embodiments, the method may include forming an intraocular lens while maintaining an accommodative state of the eye. In such embodiments, the method may exclude permitting at least a portion of the intraocular lens to become coupled to at least a portion of the capsular bag.

    摘要翻译： 将眼内透镜植入受试者的眼睛中的方法包括将眼内透镜放置在受试者的眼睛中并施用足以维持眼睛调节状态的量的药物。 该方法还包括允许眼内透镜的至少一部分变得耦合到眼睛的至少一部分，同时将眼睛保持在调节状态。 在某些实施例中，该方法可以包括在保持眼睛调节状态的同时形成眼内透镜。 在这样的实施例中，该方法可以排除允许眼内透镜的至少一部分变得联接到囊袋的至少一部分。

    Accommodating intraocular lens and method of manufacture thereof
    3.
    发明授权
    Accommodating intraocular lens and method of manufacture thereof 有权
    容纳人工晶状体及其制造方法

    公开(公告)号：US09271830B2

    公开(公告)日：2016-03-01

    申请号：US12658947

    申请日：2010-02-16

    申请人： Marlene L. Paul ,  Michael D. Lowery ,  Daniel Brady ,  Arlene Gwon

    发明人： Marlene L. Paul ,  Michael D. Lowery ,  Daniel Brady ,  Arlene Gwon

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1629 ,  A61F2/1613 ,  A61F2/1624 ,  A61F2002/1682 ,  A61F2002/1689 ,  A61F2002/16905

    摘要： An accommodating IOL comprises an optic adapted to focus light toward a retina of an eye, and a movement assembly coupled to the eye to provide effective accommodating movement, preferably axial movement, of the optic. At least a portion of the movement assembly is made from a material that is less stiff and/or more resilient than the material used to make the optic. Optionally, an outer ring or support portion made at least partially from either a relatively stiff material such as the material used in the optic or a relatively resilient material such as the material used in the movement assembly is also provided.

    摘要翻译： 容纳的IOL包括适于将光聚焦到眼睛的视网膜的光学器件和耦合到眼睛的移动组件，以提供光学器件的有效的容纳运动，优选地轴向移动。 移动组件的至少一部分由与用于制造光学元件的材料不那么坚固和/或更有弹性的材料制成。 可选地，还提供了至少部分地由相对刚性的材料制成的外环或支撑部分，例如在光学元件中使用的材料或相对弹性的材料，例如在运动组件中使用的材料。

    Accommodating intraocular lens and method of manufacture thereof
    4.
    发明授权
    Accommodating intraocular lens and method of manufacture thereof 有权
    容纳人工晶状体及其制造方法

    公开(公告)号：US07662180B2

    公开(公告)日：2010-02-16

    申请号：US10314069

    申请日：2002-12-05

    申请人： Marlene L. Paul ,  Michael D. Lowery ,  Daniel Brady ,  Arlene Gwon

    发明人： Marlene L. Paul ,  Michael D. Lowery ,  Daniel Brady ,  Arlene Gwon

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1629 ,  A61F2/1613 ,  A61F2/1624 ,  A61F2002/1682 ,  A61F2002/1689 ,  A61F2002/16905

    摘要： An accommodating IOL comprises an optic adapted to focus light toward a retina of an eye, and a movement assembly coupled to the eye to provide effective accommodating movement, preferably axial movement, of the optic. At least a portion of the movement assembly is made from a material that is less stiff and/or more resilient than the material used to make the optic. Optionally, an outer ring or support portion made at least partially from either a relatively stiff material such as the material used in the optic or a relatively resilient material such as the material used in the movement assembly is also provided.

    摘要翻译： 容纳的IOL包括适于将光聚焦到眼睛的视网膜的光学器件和耦合到眼睛的移动组件，以提供光学器件的有效的容纳运动，优选地轴向移动。 移动组件的至少一部分由与用于制造光学元件的材料不那么坚固和/或更有弹性的材料制成。 可选地，还提供了至少部分地由相对刚性的材料制成的外环或支撑部分，例如在光学元件中使用的材料或相对弹性的材料，例如在运动组件中使用的材料。

    Accommodating intraocular lens with outer support structure
    5.
    发明申请
    Accommodating intraocular lens with outer support structure 有权

    公开(公告)号：US20060161252A1

    公开(公告)日：2006-07-20

    申请号：US11322068

    申请日：2005-12-28

    申请人： Daniel Brady ,  Arlene Gwon

    发明人： Daniel Brady ,  Arlene Gwon

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1624 ,  A61F2/1629 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2/1694 ,  A61F2002/1682 ,  A61F2002/169 ,  A61F2250/006

    摘要： An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

    Accommodating diffractive intraocular lens
    6.
    发明申请
    Accommodating diffractive intraocular lens 审中-公开
    容纳衍射人工晶状体

    公开(公告)号：US20070168027A1

    公开(公告)日：2007-07-19

    申请号：US11331650

    申请日：2006-01-13

    申请人： Daniel Brady ,  Patricia Piers

    发明人： Daniel Brady ,  Patricia Piers

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1613 ,  A61F2/1635 ,  A61F2/1654 ,  A61F2250/0062

    摘要： A series of deformable, accommodating intraocular lenses is disclosed, where the series subtends a range of nominal powers. The capsular bag of the eye exerts a distorting force on the lens, thereby changing its power and allowing for accommodation. A full accommodation range is the lens power that brings a distant object into focus, subtracted from the lens power that brings a near object into focus. Each lens in the series has essentially the same shape, which is optimized to maximize the accommodation range for a given distorting force. Typically, the lenses in the series have a meniscus shape, although plano-convex and bi-convex may also be used. In order to vary the nominal power for each lens in the series, without significantly affecting the accommodation range, a diffraction grating is applied to one or both of the lens surfaces, where the grating power is different for each lens in the series.

    摘要翻译： 公开了一系列可变形的，容纳的眼内透镜，其中该系列对准一定范围的标称功率。 眼睛的囊袋在镜片上施加扭曲力，从而改变其功率并允许调节。 一个完整的住宿范围是将远距离物体聚焦的镜头力量，从将近物体聚焦的镜头力减去。 该系列中的每个透镜具有基本相同的形状，其被优化以最大化给定扭曲力的适应范围。 通常，该系列中的透镜具有弯月面形状，尽管也可以使用平凸和双凸。 为了改变串联中的每个透镜的标称功率，不会明显地影响调节范围，衍射光栅被施加到一个或两个透镜表面，其中光栅功率对于该系列中的每个透镜是不同的。

    IOL INSERTION APPARATUS AND METHOD FOR MAKING AND USING SAME
    7.
    发明申请
    IOL INSERTION APPARATUS AND METHOD FOR MAKING AND USING SAME 审中-公开
    IOL插入装置及其制造和使用方法

    公开(公告)号：US20070203502A1

    公开(公告)日：2007-08-30

    申请号：US11696811

    申请日：2007-04-05

    申请人： Harish Makker ,  Shih-Liang Yang ,  Daniel Brady ,  Robert Glick

    发明人： Harish Makker ,  Shih-Liang Yang ,  Daniel Brady ,  Robert Glick

    IPC分类号： A61F9/007

    CPC分类号： A61F2/1675 ,  A61F2/1664

    摘要： Apparatus for inserting intraocular lenses (IOLs) into eyes include a hollow tube including a material and having an interior wall defining a hollow space through which an IOL is passed and an outlet through which the IOL is passed from the hollow space into an eye, and a lubricity enhancing component physically secured to said hollow tube and concentrated at or near the interior wall in an amount effective to facilitate the passage of the IOL through the hollow space.

    摘要翻译： 用于将眼内透镜（IOL）插入眼睛的装置包括：中空管，其包括材料，并且具有限定中空空间的内壁，IOL通过该中空空间和IOL从中空空间穿过眼睛的出口;以及 润滑性增强部件物理地固定到所述中空管上并且以有效促进IOL通过中空空间的量在内壁或其附近集中。

    OPHTHALMIC LENS COMBINATIONS
    8.
    发明申请
    OPHTHALMIC LENS COMBINATIONS 审中-公开
    眼底镜组合

    公开(公告)号：US20060238702A1

    公开(公告)日：2006-10-26

    申请号：US11456521

    申请日：2006-07-10

    申请人： Robert Glick ,  Daniel Brady

    发明人： Robert Glick ,  Daniel Brady

    IPC分类号： G02C7/04

    CPC分类号： A61F2/1648 ,  A61F2/1602 ,  A61F2/1613 ,  A61F2/1629 ,  A61F2/1635 ,  A61F2002/009 ,  A61F2250/0053 ,  G02C7/00

    摘要： An ophthalmic device is provided for a patient that has a basic prescription for distant vision, the ophthalmic device including a primary optic and a supplemental optic. The primary optic is configured for placement in the eye and has a base optical power configured to substantially provide the basic prescription. The supplemental optic has an optical power that is less than the optical power of the primary optic and is configured to provide, in combination with the primary optic, a combined optical power that provides the basic prescription of the patient. In addition, at least one surface of the primary optic is configured to deform in response to an ocular force so as to modify the combined optical power by at least 1 Diopter. The ophthalmic device may further include a movement assembly operably coupled to the primary optic that is structured to cooperate with the eye to effect accommodating deformation of the primary optic in response to an ocular force produced by the eye. The movement assembly may also be configured to provide accommodating axial movement of the primary optic.

    摘要翻译： 为具有远视力的基本处方的患者提供眼科装置，该眼科装置包括主光学元件和辅助光学元件。 主要光学元件被配置为放置在眼睛中并且具有被配置为基本上提供基本处方的基本光功率。 辅助光学器件具有小于主光学器件的光功率的光功率，并且被配置为与主光学器件组合提供提供患者的基本处方的组合光功率。 此外，主光学元件的至少一个表面被配置为响应于眼睛的力而变形，以便将组合光焦度修改至少1屈光度。 眼科装置还可以包括可操作地耦合到主要光学元件的运动组件，其被构造成与眼睛配合以响应于眼睛产生的眼睛力量来实现主要光学元件的变形。 运动组件还可以被配置为提供容纳主要光学元件的轴向运动。

    Foldable intraocular lens and method of making
    9.
    发明申请
    Foldable intraocular lens and method of making 有权
    可折叠眼内透镜及其制作方法

    公开(公告)号：US20050125055A1

    公开(公告)日：2005-06-09

    申请号：US11007533

    申请日：2004-12-07

    申请人： Jim Deacon ,  David Shepherd ,  Daniel Brady ,  Marlene Paul

    发明人： Jim Deacon ,  David Shepherd ,  Daniel Brady ,  Marlene Paul

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1616

    摘要： A foldable intraocular lens for providing vision contains an optic body that includes an optical zone and a peripheral zone entirely surrounding the optical zone. The optic body has an anterior face, a substantially opposing posterior face, an optic edge, and an optical axis. The anterior face comprises a central face, a peripheral face, and a recessed annular face therebetween that is disposed posterior to the peripheral face. The intraocular lens further comprises at least one haptic that is integrally formed with the peripheral zone. The haptic comprises a distal posterior face, a proximal posterior face, and a step edge disposed at a boundary therebetween. The haptic further comprises a side edge disposed between the optic edge and the step edge. The proximal posterior face and the posterior face of the optic body form a continuous surface. An edge corner is formed by the intersection of the continuous surface with the optic edge, the side edge, and the step edge.

    摘要翻译： 用于提供视觉的可折叠眼内透镜包含光学主体，其包括光学区域和完全围绕光学区域的周边区域。 光学主体具有前表面，基本相对的后表面，光学边缘和光轴。 前表面包括设置在周边面后方的中心面，外周面和凹部的环状面。 眼内透镜还包括与周边区域整体形成的至少一个触觉部。 触觉包括远端后表面，近端后表面和设置在其边界处的台阶边缘。 触觉件还包括设置在光学边缘和台阶边缘之间的侧边缘。 光学体的近侧后表面和后表面形成连续表面。 边缘角由连续表面与光学边缘，侧边缘和台阶边缘的交点形成。