公开(公告)号：US06541048B2

公开(公告)日：2003-04-01

申请号：US09748699

申请日：2000-12-22

申请人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone ,  David L. Witkewitz

发明人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone ,  David L. Witkewitz

IPC分类号： A23G330

CPC分类号： A23G4/06 ,  A23G4/025 ,  A23G4/064 ,  A23G4/068 ,  A23G4/10 ,  A23G4/126 ,  A23G4/20 ,  A23V2002/00 ,  A61K9/0058 ,  A61K9/2086 ,  A61K9/209 ,  A61K31/426 ,  A61K33/10 ,  A23V2200/22 ,  A23V2250/64 ,  A23V2250/5028 ,  A23V2250/242 ,  A23V2250/30 ,  A61K2300/00

摘要： A method of making coated chewing gum products containing an acid blocker comprises the steps of providing chewing gum cores; providing a coating syrup comprising a bulk sweetener, providing an acid blocker, applying the coating syrup and acid blocker to the cores and drying the syrup to produce a coating on the cores, the coating containing the acid blocker.

摘要翻译： 制备含有酸阻断剂的包衣口香糖产品的方法包括提供口香糖核心的步骤; 提供包含增量甜味剂的涂层糖浆，提供酸阻断剂，将涂覆糖浆和酸阻断剂施用于核心并干燥糖浆以在芯上产生包含酸阻断剂的涂层。

公开(公告)号：US06569472B1

公开(公告)日：2003-05-27

申请号：US09654464

申请日：2000-09-01

申请人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone

发明人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone

IPC分类号： A23G330

CPC分类号： A23G4/025 ,  A23G3/343 ,  A23G4/064 ,  A23G4/20 ,  A23G2210/00

摘要： A method of making antacid coated chewing gum products comprises the steps of providing chewing gum cores; providing a coating syrup comprising a bulk sweetener and calcium carbonate having a median particle size of greater than about 3 microns and being suspended in the coating syrup; and applying the coating syrup to the cores and drying the syrup to produce a coating on the cores, the coating containing from about 25% to about 60% calcium carbonate.

摘要翻译： 制备抗酸包衣口香糖产品的方法包括提供口香糖核心的步骤; 提供包含中等粒径大于约3微米并且悬浮在涂覆糖浆中的本体甜味剂和碳酸钙的涂料浆料; 并将涂覆糖浆施加到芯上并干燥糖浆以在芯上产生涂层，该涂层含有约25％至约60％的碳酸钙。

公开(公告)号：US06579545B2

公开(公告)日：2003-06-17

申请号：US09747300

申请日：2000-12-22

申请人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone ,  John E. Hammond ,  David L. Witkewitz ,  Daniel J. Sitler ,  Raynold M. Petrocelli

发明人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone ,  John E. Hammond ,  David L. Witkewitz ,  Daniel J. Sitler ,  Raynold M. Petrocelli

IPC分类号： G33

CPC分类号： A23G4/025 ,  A23G3/343 ,  A23G4/08 ,  A23G4/20 ,  A23G2200/00 ,  A23V2002/00 ,  A61K31/341 ,  A61K31/426 ,  A61K31/80 ,  A61K2300/00 ,  A23V2200/22 ,  A23V2250/30

摘要： A method of making coated chewing gum products containing an antigas agent comprises the steps of providing chewing gum cores; providing a coating comprising a bulk sweetener; providing an antigas agent; and applying the antigas agent and coating syrup to the cores and drying the syrup to produce a coating on the cores.

公开(公告)号：US06645535B2

公开(公告)日：2003-11-11

申请号：US09747323

申请日：2000-12-22

申请人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone

发明人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip G. Schnell ,  Philip Mazzone

IPC分类号： A23G330

CPC分类号： A23G4/06 ,  A23G4/00 ,  A23G4/025 ,  A23G4/064 ,  A23G4/068 ,  A23G4/10 ,  A23G4/126 ,  A23G4/20 ,  A61K9/0058 ,  A61K9/2086 ,  A61K9/209 ,  A61K31/341 ,  A61K31/415 ,  A61K31/426 ,  A61K33/06 ,  A61K33/12 ,  A61K33/245 ,  A61K33/42 ,  A61K2300/00

摘要： A method of making antacid coated chewing gum products comprises the steps of providing chewing gum cores; providing a coating syrup comprising a bulk sweetener and a neutralizing antacid suspended in the coating syrup, the coating syrup containing from about 25% to about 50% by weight of the solids in the syrup of a neutralizing antacid, selected from the group consisting of aluminum salts, bismuth salts, magnesium salts, sodium bicarbonate, potassium bicarbonate, potassium citrate, sodium potassium tartrate, tricalcium phosphate and mixtures thereof, and applying the coating syrup to the cores and drying the syrup to produce a coating on the cores. Methods of use of the product to provide relief in the gastrointestinal tract are also included.

摘要翻译： 制备抗酸包衣口香糖产品的方法包括提供口香糖核心的步骤; 提供包含悬浮在涂覆糖浆中的增量甜味剂和中和抗酸剂的涂料糖浆，所述涂布浆液含有约25％至约50％重​​量的中和抗酸剂糖浆中的固体，所述中和抗酸剂选自铝 盐，铋盐，镁盐，碳酸氢钠，碳酸氢钾，柠檬酸钾，酒石酸钠钾，磷酸三钙及其混合物，并将涂覆糖浆施加到芯上并干燥糖浆以在芯上产生涂层。 还包括使用该产品在胃肠道中提供缓解的方法。

公开(公告)号：US06663849B1

公开(公告)日：2003-12-16

申请号：US09653669

申请日：2000-09-01

申请人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip W. Urnezis ,  Philip Mazzone

发明人： Daniel J. Zyck ,  Michael J. Greenberg ,  David G. Barkalow ,  Scott W. Marske ,  Philip W. Urnezis ,  Philip Mazzone

IPC分类号： A61K968

CPC分类号： A61K31/426 ,  A61K9/0058 ,  A61K33/10 ,  A61K2300/00

摘要： A method of making antacid coated chewing gum products comprises the steps of providing chewing gum cores; providing a coating syrup comprising a bulk sweetener, calcium carbonate and a binding agent; and applying the coating syrup to the cores and drying the syrup to produce a sugarless coating on the cores. The coating on the cores produces a high viscosity in saliva when the gum is chewed, in that 4.5 grams of said coating dispersed in 30 ml of water has a Brookfield viscosity at 23° C. of at least 1.6 centipoise.

摘要翻译： 制备抗酸包衣口香糖产品的方法包括提供口香糖核心的步骤; 提供包含本体甜味剂，碳酸钙和粘合剂的涂料浆料; 并将涂覆糖浆施加到芯上并干燥糖浆以在芯上产生无糖涂层。 当口香糖咀嚼时，芯上的涂层产生高唾液粘度，因为分散在30ml水中的4.5克所述涂层在23℃下的Brookfield粘度为至少1.6厘泊。

公开(公告)号：US20100104518A1

公开(公告)日：2010-04-29

申请号：US12444680

申请日：2007-01-16

申请人： Jianwei J. Cai ,  Minmin Tian ,  Michael J. Greenberg ,  Scott W. Marske ,  Biao Che ,  Albert H. Chapdelaine ,  Zheng Xia Han ,  Wen Xiong Huang

发明人： Jianwei J. Cai ,  Minmin Tian ,  Michael J. Greenberg ,  Scott W. Marske ,  Biao Che ,  Albert H. Chapdelaine ,  Zheng Xia Han ,  Wen Xiong Huang

IPC分类号： A61K9/68

CPC分类号： A61K9/0058 ,  A23G4/06 ,  A23G4/062 ,  A23G4/068 ,  A23G4/20

摘要： A method for producing a chewing gum with a controlled release traditional Chinese medicine active agent, as well as the chewing gum so produced, is obtained by physically modifying the release properties of the traditional Chinese medicine active agent by coating and drying. The traditional Chinese medicine active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated traditional Chinese medicine active agent is preferably then co-dried and particle sized to produce a release-modified traditional Chinese medicine active agent for use in chewing gum. The traditional Chinese medicine active agent may also be used in a coating on a chewing gum product, as part of a rolling compound applied to the chewing gum product, or as a part of the liquid in a liquid-center chewing gum product.

摘要翻译： 通过涂覆和干燥物理改变中药活性剂的释放性能，获得了具有控制释放中药活性剂的口香糖以及所生产的口香糖的方法。 中药活性剂通过包封进行包衣，通过附聚部分包被，通过吸收包埋，或通过包封，附聚和吸收的多个步骤进行处理。 然后优选涂敷的中药活性剂，同时干燥并调整颗粒大小以产生用于口香糖的释放改性的中药活性剂。 中草药活性剂也可以用作口香糖产品上的涂层，作为应用于口香糖产品的滚动化合物的一部分，或作为液体中心口香糖产品中的液体的一部分使用。