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1.发明授权Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial 失效结合多肽抗微生物剂的自我保存的多用途眼用溶液公开(公告)号：US06482799B1
公开(公告)日：2002-11-19
申请号：US09318195
申请日：1999-05-25
申请人： Daniel Tusé , Kristien Mortelmans , Leslie A. Hokama , Michael E. Selsted , Larry L. Chapoy , Michael H. Quinn
发明人： Daniel Tusé , Kristien Mortelmans , Leslie A. Hokama , Michael E. Selsted , Larry L. Chapoy , Michael H. Quinn
IPC分类号： A61K3800
CPC分类号： A61L12/14
摘要： This invention provides a novel anti-microbial system suitable for formulation in a wide variety of ophthalmic solutions. In particular the composition comprises an antimicrobial peptide that is an indolicidin and a buffer compatible with application to a mammalian eye, wherein the buffer is a Good's buffer or the buffer has a halide ion concentration less than 0.85 wt %. The compositions are useful for storing, cleaning, or disinfecting a contact lens. In particular the compositions are self-preserving upon lengthy storage, effective in cleaning and sterilizing contact lenses upon exposure of the lens to the composition, do not require the need for physical or thermal treatment of the lens and enable the immediate application of the lens to the eye without the need for neutralization, deactivation or washing.
摘要翻译： 本发明提供了适用于制备各种眼科溶液的新型抗微生物系统。 特别地，该组合物包含抗微生物肽，其是吲哚多菌素和与应用于哺乳动物眼睛相容的缓冲液，其中缓冲液是Good's缓冲液或缓冲液的卤离子浓度小于0.85wt％。 该组合物可用于储存，清洁或消毒隐形眼镜。 特别地，组合物在长时间储存时是自我保存的，在将透镜暴露于组合物时有效地清洁和消毒隐形眼镜，不需要对镜片进行物理或热处理，并且能够立即将镜片应用于 眼睛不需要中和，去激活或洗涤。
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公开(公告)号：US5272010A
公开(公告)日：1993-12-21
申请号：US768910
申请日：1991-10-01
申请人： Michael H. Quinn
发明人： Michael H. Quinn
CPC分类号： G02B1/043 , Y10T428/31504 , Y10T428/31855
摘要： Novel colored contact lens and methods for preparation thereof are described. Binding of a color coat to the lenses is accomplished by use of compounds containing the functional groups --CH.sub.2 --O--R.sup.1, wherein R.sup.1 is hydrogen or C.sub.1 to C.sub.16 alkyl, and said --CH.sub.2 --O--R.sup.1 groups are attached to a carbon atom that is part of an aromatic ring, or are attached to a nitrogen or oxygen atom.
摘要翻译： PCT No.PCT / US90 / 01868 Sec。 371日期1991年10月1日 102（e）日期1991年10月1日PCT提交1990年4月12日PCT公布。 WO90 / 12840BC出版物 日期：1990年11月1日。描述了新型有色隐形眼镜及其制备方法。 彩色涂层与透镜的结合通过使用含有官能团-CH 2 -O-R 1的化合物来实现，其中R 1是氢或C 1至C 16烷基，所述-CH 2 -O-R 1基团连接到碳原子上 其是芳环的一部分，或者连接到氮原子或氧原子上。
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公开(公告)号：US06196683B1
公开(公告)日：2001-03-06
申请号：US09298141
申请日：1999-04-23
申请人： Michael H. Quinn , Barry L. Atkins
发明人： Michael H. Quinn , Barry L. Atkins
IPC分类号： G02C704
CPC分类号： G02C7/046
摘要： A contact lens and method for making the same provides a cosmetic effect using pearlescent pigment.
摘要翻译： 隐形眼镜及其制造方法使用珠光颜料提供美容效果
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公开(公告)号：US06649722B2
公开(公告)日：2003-11-18
申请号：US09731331
申请日：2000-12-06
IPC分类号： G02C704
CPC分类号： G02B1/043 , C08F220/56 , C08F230/08 , Y10S525/937 , C08L43/04 , C08L83/04
摘要： This invention is directed to ophthalmic materials and ophthalmic lenses that are a co-polymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group-containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer, as well as optional monomers or monomer mixtures that can include a cationic monomer, a non-aromatic hydrophobic monomer and a poly(dimethylsiloxy)silyl group-containing monomer. A contact lens prepared from such a co-polymer exhibits enhanced water content, while maintaining exceptional oxygen permeability, thereby providing a lens that can be worn comfortably for prolonged periods of time. A process for the preparation of such lenses is also disclosed.
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公开(公告)号：US06634747B1
公开(公告)日：2003-10-21
申请号：US09589478
申请日：2000-06-07
申请人： Barry L. Atkins , Michael H. Quinn
发明人： Barry L. Atkins , Michael H. Quinn
IPC分类号： G02C704
摘要： Contact lenses with sample indicator marks are disclosed. Also disclosed are methods of marking and use of contact lenses with indicator marks.
摘要翻译： 公开了带有样品指示标记的隐形眼镜。 还公开了用指示标记标记和使用隐形眼镜的方法。
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公开(公告)号：US07201481B2
公开(公告)日：2007-04-10
申请号：US10470651
申请日：2003-07-09
IPC分类号： G02C7/02
CPC分类号： G02B1/043 , C08F220/56 , C08F230/08 , Y10S525/937 , C08L43/04 , C08L83/04
摘要： This invention is directed to ophthalmic materials and ophthalmic lenses that are a co-polymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group-containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer, as well as optional monomers or monomer mixtures that can include a cationic monomer, a non-aromatic hydrophobic monomer and a poly(dimethylsiloxy)silyl group-containing monomer. A contact lens prepared from such a co-polymer exhibits enhanced water content, while maintaining exceptional oxygen permeability, thereby providing a lens that can be worn comfortably for prolonged periods of time. A process for the preparation of such lenses is also disclosed.
摘要翻译： 本发明涉及作为（a）亲水性单体与（b）含三（甲硅烷氧基）甲硅烷基的单体的共聚合产物的眼科材料和眼用透镜，（c）各种各样的疏水性单体 脂族和芳族的）和通常的（d）多氟化单体，以及可以包括阳离子单体，非芳族疏水单体和含聚（二甲基甲硅烷氧基）甲硅烷基的单体的任选的单体或单体混合物。 由这种共聚物制备的隐形眼镜表现出增强的含水量，同时保持卓越的氧气渗透性，从而提供可以在较长时间内舒适佩戴的镜片。 还公开了制备这种透镜的方法。
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7.发明授权公开(公告)号：US06322214B1
公开(公告)日：2001-11-27
申请号：US09677832
申请日：2000-09-29
申请人： Barry L. Atkins , Michael H. Quinn
发明人： Barry L. Atkins , Michael H. Quinn
IPC分类号： G02C704
CPC分类号： G02C7/046
摘要： A colored contact lens comprising a non-opaque pupil section, an iris section surrounding the pupil section. A colored, opaque, intermittent pattern is deposited over the iris section using opaque elements which are indiscernible to the ordinary viewer. The elements of the pattern are of a shade which provides a contact lens capable of making subtle changes or enhancements to the color of the iris of a dark-eyed person while imparting a very natural appearance.
摘要翻译： 彩色隐形眼镜，包括不透明瞳孔部分，围绕瞳孔部分的虹膜部分。 彩色，不透明，间断的图案使用不能被普通观众忽略的不透明元件沉积在虹膜部分上。 图案的元件是阴影，其提供能够对黑眼睛的人的虹膜的颜色进行微妙变化或增强的隐形眼镜，同时赋予非常自然的外观。
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8.发明授权
公开(公告)号：US6132043A
公开(公告)日：2000-10-17
申请号：US148174
申请日：1998-09-04
申请人： Barry L. Atkins , Michael H. Quinn
发明人： Barry L. Atkins , Michael H. Quinn
IPC分类号： G02C7/04
CPC分类号： G02C7/046
摘要： A colored contact lens comprising a non-opaque pupil section, an iris section surrounding the pupil section. A colored, opaque, intermittent pattern is deposited over the iris section using opaque elements which are indiscernible to the ordinary viewer. The elements of the pattern are of a shade which provides a contact lens capable of making subtle changes or enhancements to the color of the iris of a dark-eyed person while imparting a very natural appearance.
摘要翻译： 彩色隐形眼镜，包括不透明瞳孔部分，围绕瞳孔部分的虹膜部分。 彩色，不透明，间断的图案使用不能被普通观众忽略的不透明元件沉积在虹膜部分上。 图案的元件是阴影，其提供能够对黑眼睛的人的虹膜的颜色进行微妙变化或增强的隐形眼镜，同时赋予非常自然的外观。
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公开(公告)号：US4852949A
公开(公告)日：1989-08-01
申请号：US102130
申请日：1987-12-07
申请人： Michael H. Quinn , Paul H. Quinn
发明人： Michael H. Quinn , Paul H. Quinn
IPC分类号： B60B39/10
CPC分类号： B60B39/10
摘要： This invention consists of a funnel mounted near the wheel well of a vehicle, which contains marble chips and is activated when a button located on the steering wheel is depressed. The flow of marble chips continues until the button is depressed a second time.
摘要翻译： 本发明包括安装在车辆的车轮孔附近的漏斗，其包含大理石碎片，并且当按下位于方向盘上的按钮时被激活。 大理石碎片的流动继续，直到按钮第二次被按下。
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