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    Ultrasonic imaging system and method for displaying tissue perfusion and other parameters varying with time
    1.
    发明授权
    Ultrasonic imaging system and method for displaying tissue perfusion and other parameters varying with time 有权
    超声波成像系统和显示组织灌注等参数随时间变化的方法

    公开(公告)号：US06692438B2

    公开(公告)日：2004-02-17

    申请号：US10025200

    申请日：2001-12-18

    申请人： Danny M. Skyba ,  Damien Dolimier ,  Jeffry E. Powers

    发明人： Danny M. Skyba ,  Damien Dolimier ,  Jeffry E. Powers

    IPC分类号： A61B800

    CPC分类号： A61B8/463 ,  A61B8/065 ,  A61B8/08 ,  A61B8/0883 ,  A61B8/481 ,  A61B8/543 ,  G01S7/52038 ,  G01S15/8993

    摘要： A method and system for displaying a parametric image showing tissue perfusion includes an ultrasonic imaging system coupled to an ECG device. The ECG device triggers the imaging system to obtain contrast image data showing tissue perfusion at a respective predetermined time during each of a plurality of heartbeats. Parametric image data for discrete locations in the area of interest such as the myocardium is determined from the temporal contrast data acquired during reperfusion of the tissue in the area of interest. The parameters are mapped to a display value such as color to produce a parametric perfusion ultrasound image. Sequences of images may be produced which depict both perfusion characteristics and dynamic wall motion of the myocardium in a common image sequence.

    摘要翻译： 用于显示显示组织灌注的参数图像的方法和系统包括耦合到ECG装置的超声成像系统。 ECG装置触发成像系统以获得在多个心跳期间的每个期间在相应的预定时间显示组织灌注的对比度图像数据。 在感兴趣区域（例如心肌）中的离散位置的参数图像数据是从感兴趣区域中的组织再灌注期间获取的时间对比数据确定的。 将参数映射到诸如颜色的显示值以产生参数灌注超声图像。 可以产生描绘在共同图像序列中的心肌的灌注特性和动态壁运动的图像序列。

    System and method for comparing ultrasound images corresponding to two user-selected data points
    2.
    发明授权
    System and method for comparing ultrasound images corresponding to two user-selected data points 有权
    用于比较与两个用户选择的数据点相对应的超声图像的系统和方法

    公开(公告)号：US07593554B2

    公开(公告)日：2009-09-22

    申请号：US10264029

    申请日：2002-10-03

    申请人： Edward A. Miller ,  Rohit Garg ,  Damien Dolimier ,  Danny M. Skyba

    发明人： Edward A. Miller ,  Rohit Garg ,  Damien Dolimier ,  Danny M. Skyba

    IPC分类号： G06K9/00

    CPC分类号： A61B8/469 ,  A61B8/461 ,  A61B8/463 ,  G06F19/00 ,  G06F19/321 ,  G06T19/00 ,  G06T2210/41 ,  G06T2219/028

    摘要： A system and method are provided for simplifying off-line quantification of ultrasound images by displaying a graphical user interface showing a real-time ultrasound image for enabling a user to freeze the real-time ultrasound image to display an image sequence capable of being modified and played back by the user. The graphical user interface displays graphs or curves providing data related to the ultrasound images. Each data point on the curves represents one ultrasound image of the ultrasound images. When the user selects a particular data point on a curve of a graph, the corresponding ultrasound image is displayed by the graphical user interface. The user can then select another data point on the same curve or another curve to display another corresponding ultrasound image. The two ultrasound image framescan then be compared. The system and method of the present invention further provide the ability for a user to select a region of interest within one of the displayed images to display parameters associated with the selected region of interest for the two ultrasound images.

    摘要翻译： 提供了一种系统和方法，用于通过显示示出实时超声图像的图形用户界面来简化超声图像的离线量化，以使用户能够冻结实时超声图像以显示能够被修改的图像序列， 由用户播放。 图形用户界面显示提供与超声图像有关的数据的图形或曲线。 曲线上的每个数据点表示超声图像的一个超声图像。 当用户选择曲线曲线上的特定数据点时，图形用户界面显示相应的超声波图像。 然后，用户可以在相同曲线或另一曲线上选择另一个数据点，以显示另一个对应的超声图像。 然后可以比较两个超声图像帧。 本发明的系统和方法还提供了用户在所显示的图像之一内选择感兴趣区域的能力，以显示与所选择的两个超声图像的感兴趣区域相关联的参数。

    System and method for brightening a curve corresponding to a selected ultrasound ROI
    3.
    发明授权
    System and method for brightening a curve corresponding to a selected ultrasound ROI 有权
    用于使对应于所选择的超声ROI的曲线变亮的系统和方法

    公开(公告)号：US06685642B1

    公开(公告)日：2004-02-03

    申请号：US10264066

    申请日：2002-10-03

    申请人： Rohit Garg ,  Edward A. Miller ,  Damien Dolimier ,  Danny M. Skyba

    发明人： Rohit Garg ,  Edward A. Miller ,  Damien Dolimier ,  Danny M. Skyba

    IPC分类号： A61B800

    CPC分类号： A61B8/467 ,  A61B8/00 ,  A61B8/463 ,  A61B8/465 ,  A61B8/469

    摘要： A system and method are provided for simplifying off-line quantification of ultrasound images by displaying a graphical user interface showing a real-time ultrasound image for enabling a user to freeze the real-time ultrasound image to display an image sequence capable of being modified and played back by the user. Upon freezing the real-time image, the graphical user interface displays a tagging system having a corresponding identification tag for each ultrasound image of the image sequence. The graphical user interface further displays time intensity curves each corresponding to an ROI in the frozen image. When the user selects a particular ROI in the frozen image, the curve corresponding to the selected ROI is brightened and the other curves are dimmed.

    摘要翻译： 提供了一种系统和方法，用于通过显示示出实时超声图像的图形用户界面来简化超声图像的离线量化，以使用户能够冻结实时超声图像以显示能够被修改的图像序列， 由用户播放。 在冻结实时图像时，图形用户界面显示具有用于图像序列的每个超声图像的相应识别标签的标签系统。 图形用户界面还显示每个对应于冻结图像中的ROI的时间强度曲线。 当用户在冻结图像中选择特定的ROI时，对应于所选择的ROI的曲线变亮并且其它曲线变暗。

    Realtime ultrasonic imaging of perfusion using ultrasonic contrast agents
    4.
    发明授权
    Realtime ultrasonic imaging of perfusion using ultrasonic contrast agents 失效
    使用超声造影剂实时灌注超声成像

    公开(公告)号：US06171246B2

    公开(公告)日：2001-01-09

    申请号：US09302063

    申请日：1999-04-29

    申请人： Michalakis Averkiou ,  Jeffry E. Powers ,  Matthew Bruce ,  Danny M. Skyba

    发明人： Michalakis Averkiou ,  Jeffry E. Powers ,  Matthew Bruce ,  Danny M. Skyba

    IPC分类号： A61B814

    CPC分类号： A61B8/481 ,  A61B8/543 ,  G01S7/52038 ,  G01S7/52039 ,  G01S15/8981

    摘要： Perfusion of tissue such as the myocardium by a microbubble contrast agent is imaged in realtime by a multiple pulse technique which uses low power transmit pulses which are sufficient to elicit a harmonic response from the microbubbles but are not high enough in power to cause substantial destruction to the microbubbles. In a preferred embodiment the realtime microbubble image sequence is displayed in color, overlaid with a grayscale image of the surrounding tissue in the region being imaged.

    摘要翻译： 通过微泡造影剂对诸如心肌的组织灌注通过多脉冲技术实时成像，所述多脉冲技术使用足以引起来自微泡的谐波响应的低功率发射脉冲，但是不足以引起大量破坏 微泡。 在优选实施例中，实时微泡图像序列以彩色显示，并与被成像区域中的周围组织的灰度图像重叠。