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11 条记录 (耗时 0.022 秒)

    Sensor dispensing device
    1.
    发明授权
    Sensor dispensing device 有权
    传感器分配装置

    公开(公告)号：US07264139B2

    公开(公告)日：2007-09-04

    申请号：US10755712

    申请日：2004-01-12

    申请人： David Brickwood ,  Graeme Maisey ,  Stuart Richard May

    发明人： David Brickwood ,  Graeme Maisey ,  Stuart Richard May

    IPC分类号： B65H59/02

    CPC分类号： G01N33/48757

    摘要： A sensor dispensing device (1) comprises a cartridge (2) having an outer casing (11) and a plurality of sensors (6) arranged one upon another in a stack. The cartridge has a first dispensing end (13) and a second opposing end (14) spaced a fixed distance apart, and the cartridge includes a first aperture (15) for the ejection of a sensor closest to the first end and a second aperture (16) opposed to the first aperture, for access by a pushing member (25). The first aperture and the second aperture are each provided with compliant sealing means (17) which are at least partly disposed outside the outer casing. The sealing means have first and second sealing surfaces which are capable of co-operating to releasably form a substantially moisture-tight seal when acted upon by suitable clamping forces. The device has a housing (34) for receiving the cartridge. For each of the compliant sealing means (17) there is a pair of clamping members (4, 33) for releasably clamping the sealing means to form a substantially moisture-tight seal. The device has a pushing member (25) for reversible insertion through the second aperture when the sealing means are not clamped, for pushing the sensor closest to the first end through the first aperture to a dispensed position.

    摘要翻译： 传感器分配装置（1）包括具有外壳（11）的盒（2）和在堆叠中彼此彼此排列的多个传感器（6）。 盒具有间隔开固定距离的第一分配端（13）和第二相对端（14），并且盒包括用于喷射最靠近第一端的传感器的第一孔（15）和第二孔（ 16）与第一孔相对，用于由推动构件（25）进入。 第一孔和第二孔各自设置有柔性密封装置（17），其至少部分地设置在外壳的外部。 密封装置具有第一和第二密封表面，当被合适的夹持力作用时，第一和第二密封表面能够协同操作以可释放地形成基本上不透气的密封。 该装置具有用于容纳盒的壳体（34）。 对于每个柔性密封装置（17），存在一对夹紧构件（4,33），用于可释放地夹紧密封装置以形成基本上不透气的密封。 当密封装置未被夹紧时，装置具有推动构件（25），用于通过第二孔可逆地插入，用于将最靠近第一端的传感器通过第一孔推到分配位置。

    Sensor dispensing device
    5.
    发明授权
    Sensor dispensing device 有权
    传感器分配装置

    公开(公告)号：US06997343B2

    公开(公告)日：2006-02-14

    申请号：US10233265

    申请日：2002-08-30

    申请人： Stuart R. May ,  David Brickwood ,  Graeme A. Maisey

    发明人： Stuart R. May ,  David Brickwood ,  Graeme A. Maisey

    IPC分类号： B65H1/08

    CPC分类号： G01N33/48757 ,  B65H1/00 ,  B65H2402/41 ,  B65H2407/32

    摘要： An embodiment of a sensor dispensing device for dispensing sensors for measuring analyte concentration in a fluid includes a cartridge assembly (32) having a housing (70) with an opening and means (16) for making a moisture-proof seal around the opening. A stack of sensors (12) is stored in the housing (70) and urged through the opening towards a stop member (73) by spring means. The device is provided with an externally actuable pusher (18) for breaking the seal and for pushing a single sensor from the housing.

    摘要翻译： 用于分配用于测量流体中的分析物浓度的传感器的传感器分配装置的实施例包括具有开口的壳体（70）和用于在开口周围形成防潮密封的装置（16）的盒组件（32）。 一组传感器（12）存储在壳体（70）中，并通过弹簧装置通过开口朝着止动构件（73）推动。 该装置设置有用于破坏密封件并将单个传感器从壳体推出的外部可致动推动器（18）。

    Devices for motile sperm separation
    6.
    发明申请
    Devices for motile sperm separation 审中-公开
    移动精子分离装置

    公开(公告)号：US20050158700A1

    公开(公告)日：2005-07-21

    申请号：US11080928

    申请日：2005-03-16

    申请人： David Brickwood

    发明人： David Brickwood

    IPC分类号： C12M1/34 ,  A01N1/02

    CPC分类号： C12M41/46 ,  C12N5/061 ,  G01N2800/367

    摘要： Device (10, 110) for separating motile sperm from a sample (100, 200), comprises a vessel (15, 115) having an inlet port (20, 120), an outlet port (35, 135) which is initially closed, a medium (40, 140) into which motile sperm in the sample (100, 200) can migrate into the vessel (15, 115) via the inlet (20, 120), and an actuator (50, 150), the operation of which opens the outlet (35, 135), thereby allowing the medium (40, 140) to flow out of the vessel (15, 115) through the outlet (35, 135). The medium (40, 140) in the vessel (15, 115) is initially prevented from flowing through the outlet (35, 135), thus allowing an incubation period which allows motile sperm sufficient time to migrate from the sample (100, 200) into the medium (40, 140) before the medium (40, 140) leaves the vessel (35, 135). The device (10, 110) preferably comprises a spermatozoa detector in communication with the outlet. In devices for separating sperm, capillary flow takes place through non-fibrous material, such as the space between sheets (81a and 81b; 181a and 181b) of closely-juxtaposed material. A device for separating motile and non-motile sperm includes a temperature sensor, a heat source (70, 170) and, optionally, a temperature regulator.

    摘要翻译： 用于将样品（100,200）分离运动精子的装置（10,110）包括具有入口端口（20,120），初始关闭的出口（35,135）的容器（15,115） 一种介质（40,140），其中样品（100,200）中的活动精子可以经由所述入口（20,120）迁移到所述容器（15,115）中的致动器（50,150），所述操作 其打开出口（35,135），从而允许介质（40,140）通过出口（35,135）从容器（15,115）流出。 最初防止容器（15,115）中的介质（40,140）流过出口（35,135），从而允许允许活动精子足够的时间从样品（100,200）迁移的潜伏期， 在介质（40,140）离开容器（35,135）之前，进入介质（40,140）。 装置（10,110）优选地包括与出口连通的精子检测器。 在用于分离精子的装置中，毛细管流动通过非纤维材料发生，例如紧密并排的材料的片材（81a和81b; 181a和181b之间）之间的空间。 用于分离运动和非活动精子的装置包括温度传感器，热源（70,170）和任选的温度调节器。

    Device for motile sperm separation
    10.
    发明授权
    Device for motile sperm separation 失效
    移动精子分离装置

    公开(公告)号：US07179641B2

    公开(公告)日：2007-02-20

    申请号：US10203318

    申请日：2001-02-16

    申请人： David Brickwood

    发明人： David Brickwood

    IPC分类号： C12M1/34

    CPC分类号： G01N33/689 ,  C12N5/0612 ,  G01N2333/70596 ,  G01N2800/367

    摘要： An apparatus for separating and detecting motile spermatozoa in a liquid sample, comprises: a separation vessel including (i) an inlet port, (ii) an outlet port arranged to be opened, (iii) a separation medium into which motile spermatozoa in the sample can flow via the inlet port, and (iv) an actuator operable to open the outlet port for allowing the separation medium to flow out of the vessel through the outlet port; and a spermatozoa detection device including (i) an application zone in communication with the outlet port, (ii) a detection zone, in which presence of spermatozoa can be detected, and (iii) a reagent zone containing a reagent which is capable of reacting with spermatozoa to facilitate detection of the spermatozoa in the detection zone, with the application zone, the detection zone and the reagent zone being arranged to permit capillary flow of spermatozoa from the application zone to the detection zone.

    摘要翻译： 一种用于分离和检测液体样品中的活动精子的装置，包括：分离容器，包括（i）入口端口，（ii）布置成打开的出口端口，（iii）样品中的活动精子中的分离介质 可以通过入口端口流动，和（iv）致动器，其可操作以打开出口，用于允许分离介质通过出口端口流出容器; 以及精子检测装置，其包括：（i）与所述出口连通的应用区域，（ii）可以检测精子存在的检测区域，以及（iii）含有能够反应的试剂的试剂区域 用精子促进检测区中精子的检测，其中应用区域，检测区和试剂区被布置成允许精子从应用区域到检测区域的毛细血管流动。