公开(公告)号：US20100011007A1

公开(公告)日：2010-01-14

申请号：US12497408

申请日：2009-07-02

申请人： David D. Bettger ,  Ismael Rodriguez ,  Kevin A. Stone ,  Dennis L. Kuehn ,  Marc A. Peters ,  David H. Wagner

发明人： David D. Bettger ,  Ismael Rodriguez ,  Kevin A. Stone ,  Dennis L. Kuehn ,  Marc A. Peters ,  David H. Wagner

IPC分类号： G06F17/30 ,  G06F12/00 ,  G06F12/14

CPC分类号： H04L63/105 ,  H04L67/1097

摘要： In accordance with one or more embodiments of the present disclosure, systems and methods described herein provide for transferring data over one or more networks. A storage area network is adapted to communicate with the one or more networks. A first component is adapted to route data to and from the storage area network. A second component is adapted to route data to and from the storage area network. A gateway component is adapted to control the routing of data between the first and second components and the storage area network. The storage area network is adapted to separate metadata from the data and store the metadata in a secure server positioned behind the gateway component.

摘要翻译： 根据本公开的一个或多个实施例，本文所述的系统和方法提供用于通过一个或多个网络传送数据。 存储区域网络适于与一个或多个网络进行通信。 第一组件适于将数据路由到存储区域网络和从存储区域网络路由数据。 第二组件适于将数据路由到存储区域网络和从存储区域网络路由数据。 网关组件适于控制第一和第二组件与存储区域网络之间的数据路由。 存储区域网络适于从数据中分离元数据，并将元数据存储在位于网关组件后面的安全服务器中。

公开(公告)号：US20110229495A1

公开(公告)日：2011-09-22

申请号：US12397063

申请日：2009-03-03

申请人： David H. Wagner

发明人： David H. Wagner

IPC分类号： A61K39/395 ,  G01N33/566 ,  A61K38/02 ,  A61K31/7105 ,  A61K38/10 ,  A61K38/16 ,  A61K31/352 ,  A61P37/02

CPC分类号： G01N33/564 ,  C07K16/2812 ,  C07K16/2878 ,  G01N33/505 ,  G01N33/6893 ,  G01N2333/70514 ,  G01N2333/70578 ,  G01N2800/042 ,  G01N2800/24

摘要： The present invention provides a new method for the prediction of, or diagnosis of, auto-immune diseases, thereby alerting the subject to the presence of, or propensity to develop, an auto-immune disease so that preventative or therapeutic regiments may be initiated or changed so as to treat, modulate or prevent expansion of the CD4loCD40hi T cell population responsible for the destructive inflammation. The invention also discloses agents which modulate, treat or prevent expansion of CD4loCD40hi T cells. In one embodiment, the method is predictive of type 1 diabetes.

摘要翻译： 本发明提供了一种用于预测或诊断自身免疫疾病的新方法，从而提醒受试者存在或倾向于发展自身免疫疾病，从而可能启动预防或治疗团 改变以治疗，调节或预防负责破坏性炎症的CD4loCD40hi T细胞群的扩增。 本发明还公开了调节，治疗或预防CD4loCD40hi T细胞扩增的药剂。 在一个实施方案中，该方法是预测1型糖尿病。

公开(公告)号：US06286570B1

公开(公告)日：2001-09-11

申请号：US09658686

申请日：2000-09-08

申请人： Norman E. Murray ,  David H. Wagner ,  James A. Higgins ,  Thomas D. Johel

发明人： Norman E. Murray ,  David H. Wagner ,  James A. Higgins ,  Thomas D. Johel

IPC分类号： B27M1100

CPC分类号： B25D1/04 ,  E01B3/06

摘要： The anti-splitting device of the present invention has a central-web portion and a pair of end web portions, which are joined adjacent to their midpoints to opposite ends of the central web portion to provide the device with generally I-shaped cross-sectional configurations. The web portions have first side edges tapered to define a cutting edge and second side edges serving to define a planar driven surface disposed parallel to the cutting edge. And on the central web portion are at least two projections to upstand from driven surface. The projections are adapted to removably attach the device to a driver employed to insert the device into a log. The driver of the present invention is preferably in the form of a manually operational hammer having a planar driver surface of circular plan form configuration and a circular groove that has an outer diameter equidistant and an inner diameter equidistant from a given fixed point, the center of the planar driving surface. The groove receives the projections and contacts a predetermined portion of the projections; the projections exert a force on either the outer diameter or the inner diameter, and do not contact both diameters at the same time. The device can then be freely rotated in the groove to obtain a desired position on the driver surface.

摘要翻译： 本发明的防分解装置具有中央腹板部分和一对端部腹板部分，它们与中心腹板部分的相对端相接近，以使该装置具有大致I形的横截面 配置 腹板部分具有锥形以限定切割边缘的第一侧边缘，并且第二侧边缘用于限定平行于切割边缘设置的平面驱动表面。 并且在中心腹板部分上具有至少两个从被驱动表面竖立的突起。 这些突起适于将该装置可移除地附接到用于将装置插入原木的驱动器。 本发明的驱动器优选地是具有圆形平面形式构造的平面驱动器表面的手动操作锤的形式，以及具有与给定固定点等距的外径等距和内径的圆形槽， 平面驱动面。 凹槽接收突起并接触突起的预定部分; 突起在外径或内径上施加力，并且不同时接触两个直径。 然后，该装置可以在凹槽中自由旋转以获得驾驶员表面上的期望位置。